OR2G6 Olfactory Receptor
| Gene Symbol | OR2G61 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | G |
| Pseudogene | No |
| CORP pseudogene probability score | |
| Aliases | |
| External Ids | HGNC: 27019 |
| Build #39 labels | |
| Chromosomal location | 1:248,521,647-248,522,594 (+) |
| Cluster | 1@248 |
| Synteny | CLIC#5 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2G3 | 65.35% | 303 |
| OR2G2 | 64.95% | 311 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2B7 | 63% | 304 |
| Mouse | Or2y1d | 62% | 301 |
| Rat | Or2w6 | 62% | 305 |
| Cow | OR2G27 | 69% | 305 |
| Orang | OR2G6B | 96% | 316 |
| Horse | OR2G28 | 69% | 312 |
| Chimp | OR2G6P | 96% | 305 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC137266 |
Sequence information
| Nucleotide sequence |
|Strand=+|Length=ATGGAGGAAACCAACAACAGCTCTGAAAAGGGATTTCTTCTCC TGGGATTTTCAGATCAGCCTCAGCTAGAGAGGTTTCTTTTTGCCATCATTTTGTACTTCT ACGTCTTGAGCCTTCTGGGGAACACTGCCCTCATACTAGTATGTTGTCTGGACTCCAGAC TCCACACTCCAATGTACTTCTTCCTCAGCAACCTCTCGTGTGTGGACATCTGCTTTACCA CCAGTGTTGCCCCACAGTTGCTGGTTACCATGAATAAGAAAGACAAAACCATGAGCTACG GTGGCTGTGTGGCCCAGCTCTATGTGGCCATGGGGTTGGGCTCGTCTGAGTGTATTCTCT TGGCCGTCATGGCTTATGACCGCTATGCTGCTGTCTGCCGGCCACTGCGCTACATAGCCA TTATGCACCCCAGGTTCTGTGCGTCTCTGGCCGGTGGAGCATGGCTCAGCGGCCTCATCA CCTCCCTAATTCAGTGCTCCCTCACTGTGCAGCTGCCCCTCTGTGGTCATCGCACACTGG ATCATATTTTCTGTGAGGTGCCAGTGCTCATCAAACTGGCCTGTGTGGATACGACTTTCA ACGAGGCAGAACTCTTTGTGGCCAGTGTAGTCTTTCTAATTGTCCCGGTGTTACTCATCT TAGTCTCCTATGGCTTTATCACTCAAGCTGTGTTAAGGATAAAATCAGCTGCGGGCCGCC AAAAGGCCTTTGGGACCTGTTCGTCTCACCTGGTTGTGGTCATCATTTTCTATGGGACCA TCATATTCATGTACCTTCAACCGGCCAATAGGAGATCCAAAAACCAGGGAAAGTTTGTTT CTCTTTTCTATACCATAGTCACCCCACTTTTAAACCCCATTATCTACACTCTGAGAAACA AAGATGTGAAAGGGGCCTTGAGGACCCTGATACTGGGTAGTGCTGCTGGACAAAGCCACA AGGAC |
| Conceptual translation |
|Strand=+|Length=MEETNNSSEKGFLLLGFSDQPQLERFLFAIILYFYVLSLLGNT ALILVCCLDSRLHTPMYFFLSNLSCVDICFTTSVAPQLLVTMNKKDKTMSYGGCVAQLYV AMGLGSSECILLAVMAYDRYAAVCRPLRYIAIMHPRFCASLAGGAWLSGLITSLIQCSLT VQLPLCGHRTLDHIFCEVPVLIKLACVDTTFNEAELFVASVVFLIVPVLLILVSYGFITQ AVLRIKSAAGRQKAFGTCSSHLVVVIIFYGTIIFMYLQPANRRSKNQGKFVSLFYTIVTP LLNPIIYTLRNKDVKGALRTLILGSAAGQSHKD Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 248,685,122 | 248,685,122 | NS | A/G | M/V | rs58955396 (DbSNP) |
| 1 | 248,685,719 | 248,685,719 | NS | A/T | M/L | rs9330305 (DbSNP) |
| 1 | 248,685,253 | 248,685,253 | SYN | C/T | Y/Y | rs9727474 (DbSNP) |
| 1 | 248,522,418 | 248,522,418 | NS | A/T | M/L | 1000GP (CEU, CHBJPT) |
| 1 | 248,521,952 | 248,521,952 | SYN | T/C | Y/Y | 1000GP (CEU, CHBJPT) |
| 1 | 100 | -100 | NS | A/G | M/V | 1000GP (YRI, YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | T/C | Y/Y | 1000GP (YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 248,644,944 | 248,790,408 | CopyNumber | Variation_0263 (DGV) |
| 1 | 248,595,681 | 248,817,382 | CopyNumber | Variation_2359 (DGV) |
| 1 | 248,500,109 | 248,865,374 | CopyNumber | Variation_3340 (DGV) |
| 1 | 248,060,959 | 249,167,690 | CopyNumber | Variation_8354 (DGV) |
| 1 | 248,522,680 | 249,158,239 | CopyNumber | Variation_8355 (DGV) |
| 1 | 248,242,528 | 248,817,382 | CopyNumber | Variation_8935 (DGV) |
| 1 | 248,626,918 | 248,830,541 | Inversion | Variation_37092 (DGV) |
| 1 | 248,646,428 | 248,728,407 | Inversion | Variation_59670 (DGV) |
| 1 | 248,684,948 | 248,685,898 | InDel | Variation_41247 (DGV) |
| 1 | 248,684,848 | 248,687,895 | CopyNumber | #34 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| V48I | G152S | I158M | Y218D | V248I | M258L | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|
| 1 | V | G | I | Y | V | M | 82.80 | 0.765 |
| 2 | V | G | I | Y | V | L | 15.44 | 0.765 |
| 3 | V | G | M | Y | V | M | 1.08 | 0.765 |
| 4 | V | S | I | Y | I | M | 0.31 | 0.765 |
| 5 | I | G | I | Y | V | M | 0.23 | 0.740 |
| 6 | V | G | I | D | V | M | 0.15 | 0.765 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2G6.aApr07-unspliced | main_exon | CDS | chr1 | 248,521,647 | 248,522,594 | + |
| 3UTR | chr1 | 248,522,594 | 248,522,597 | + | ||