OR2T2 Olfactory Receptor
| Gene Symbol | OR2T21 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | T |
| Pseudogene | No |
| CORP pseudogene probability score | 0.05 (functional) |
| Aliases | OR1-43, HsOR1.5.41 |
| External Ids | HGNC: 14725 GeneBank: AF399479, BK004462, NM_001004136 |
| Build #39 labels | OR2T2 |
| Chromosomal location | 1:248,452,798-248,453,769 (+) |
| Cluster | 1@248 |
| Synteny | CLIC#5 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2T35 | 99.38% | 322 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2T11 | 72% | 311 |
| Mouse | Or2t35 | 83% | 321 |
| Rat | Or2t35 | 86% | 321 |
| Cow | OR2T11 | 74% | 303 |
| Orang | OR2T2P | 95% | 317 |
| Orang | OR2T2BP | 95% | 284 |
| Horse | OR2T2C | 81% | 321 |
| Chimp | OR2T11 | 71% | 311 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136962 |
Sequence information
| Nucleotide sequence |
ATGGGCATGGAGGGTCTTCTCCAGAACTCCACTAACTTCGTCCTCACAGGCCTCATCACC CATCCTGCCTTCCCCGGGCTTCTCTTTGCAATAGTCTTCTCCATCTTTGTGGTGGCTATA ACAGCCAACTTGGTCATGATTCTGCTCATCCACATGGACTCCCGCCTCCACACACCCATG TACTTCTTGCTCAGCCAGCTCTCCATCATGGATACCATCTACATCTGTATCACTGTCCCC AAGATGCTCCAGGACCTCCTGTCCAAGGACAAGACCATTTCCTTCCTGGGCTGTGCAGTT CAGATCTTCCTCTACCTGACCCTGATTGGAGGGGAATTCTTCCTGCTGGGTCTCATGGCC TATGACCGCTATGTGGCTGTGTGCAACCCTCTACGGTACCCTCTCCTCATGAACCGCAGG GTTTGCTTATTCATGGTGGTCGGCTCCTGGGTTGGTGGTTCCTTGGATGGGTTCATGCTG ACTCCTGTCACTATGAGTTTCCCCTTCTGTAGATCCCGAGAGATCAATCACTTTTTCTGT GAGATCCCAGCCGTGCTGAAGTTGTCTTGCACAGACACGTCACTCTATGAGACCCTGATG TATGCCTGCTGCGTGCTGATGCTGCTTATCCCTCTATCTGTCATCTCTGTCTCCTACACG CACATCCTCCTGACTGTCCACAGGATGAACTCTGCTGAGGGCCGGCGCAAAGCCTTTGCT ACGTGTTCCTCCCACATTATGGTGGTGAGCGTTTTCTACGGGGCAGCCTTCTACACCAAC GTGCTGCCCCACTCCTACCACACTCCAGAGAAAGATAAAGTGGTGTCTGCCTTCTACACC ATCCTCACCCCCATGCTCAACCCACTCATCTACAGCTTGAGGAATAAAGATGTGGCTGCA GCTCTGAGGAAAGTACTAGGGAGATGTGGTTCCTCCCAGAGCATCAGGGTGGCGACTGTG ATCAGGAAGGGC |
| Conceptual translation |
MEGLLQNSTNFVLTGLITHPAFPGLLFAIVFSIFVVAITANLVMILLIHMDSRLHTPMYF LLSQLSIMDTIYICITVPKMLQDLLSKDKTISFLGCAVQIFLYLTLIGGEFFLLGLMAYD RYVAVCNPLRYPLLMNRRVCLFMVVGSWVGGSLDGFMLTPVTMSFPFCRSREINHFFCEI PAVLKLSCTDTSLYETLMYACCVLMLLIPLSVISVSYTHILLTVHRMNSAEGRRKAFATC SSHIMVVSVFYGAAFYTNVLPHSYHTPEKDKVVSAFYTILTPMLNPLIYSLRNKDVAAAL RKVLGRCGSSQSIRVATVIRKG Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 248,616,408 | 248,616,408 | NS | C/T | L/F | rs73147579 (DbSNP) |
| 1 | 248,453,107 | 248,453,107 | NS | C/T | L/F | 1000GP (CEU, CHBJPT) |
| 1 | 248,453,100 | 248,453,100 | SYN | G/A | Q/Q | 1000GP (CHBJPT) |
| 1 | 100 | -100 | SYN | G/A | Q/Q | 1000GP (YRI) |
| 1 | 100 | -100 | NS | C/T | L/F | 1000GP (YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 248,595,681 | 248,817,382 | CopyNumber | Variation_2359 (DGV) |
| 1 | 248,500,109 | 248,865,374 | CopyNumber | Variation_3340 (DGV) |
| 1 | 248,610,257 | 248,646,763 | CopyNumber | Variation_6817 (DGV) |
| 1 | 248,060,959 | 249,167,690 | CopyNumber | Variation_8354 (DGV) |
| 1 | 248,522,680 | 249,158,239 | CopyNumber | Variation_8355 (DGV) |
| 1 | 248,242,528 | 248,817,382 | CopyNumber | Variation_8935 (DGV) |
| 1 | 248,616,113 | 248,619,344 | CopyNumber | Variation_30466 (DGV) |
| 1 | 248,604,260 | 248,635,197 | CopyNumber | Variation_71754 (DGV) |
| 1 | 248,609,916 | 248,625,792 | CopyNumber | Variation_71757 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| % Freq | CORP | |||
|---|---|---|---|---|
| 1 | 89.37 | 0.132 | ||
| 2 | 10.34 | 0.132 | ||
| 3 | 0.29 | 0.132 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2T2.aApr07-unspliced | main_exon | CDS | chr1 | 248,452,798 | 248,453,769 | + |
| 3UTR | chr1 | 248,453,769 | 248,453,772 | + | ||