OR2T3 Olfactory Receptor
| Gene Symbol | OR2T31 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | T |
| Pseudogene | No |
| CORP pseudogene probability score | |
| Aliases | HsOR1.5.42, ORL3040 |
| External Ids | HGNC: 14727 GeneBank: AB065612, NM_001005495 ORDB: ORL3040 |
| Build #39 labels | OR2T3 |
| Chromosomal location | 1:248,473,351-248,474,304 (+) |
| Cluster | 1@248 |
| Synteny | CLIC#5 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2T34 | 98.11% | 318 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2T4D | 69% | 302 |
| Mouse | Or2t29 | 66% | 310 |
| Rat | Or2t29 | 64% | 310 |
| Cow | OR2T3B | 80% | 318 |
| Orang | OR2T4 | 67% | 301 |
| Horse | OR2T79 | 68% | 304 |
| Chimp | OR2T3BP | 97% | 321 |
| Chimp | OR2T3P | 97% | 318 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136916 |
Sequence information
| Nucleotide sequence |
ATGTGCTCAGGGAATCAGACTTCTCAGAATCAAACAGCAAGCACTGATTTCACCCTCACG GGACTCTTTGCTGAGAGCAAGCATGCTGCCCTCCTCTACACCGTGACCTTCCTTCTTTTC TTGATGGCCCTCACTGGGAATGCCCTCCTCATCCTCCTCATCCACTCAGAGCCCCGCCTC CACACCCCCATGTACTTCTTCATCAGCCAGCTCGCGCTCATGGATCTCATGTACCTATGC GTGACTGTGCCCAAGATGCTTGTGGGCCAGGTCACTGGAGATGATACCATTTCCCCGTCA GGCTGTGGGATCCAGATGTTCTTCTACCTGACCCTGGCTGGAGCTGAGGTTTTCCTCCTG GCTGCCATGGCCTATGACCGATATGCTGCTGTTTGCAGACCTCTCCATTACCCACTGCTG ATGAACCAGAGGGTGTGCCAGCTCCTGGTGTCAGCCTGCTGGGTTTTGGGAATGGTTGAT GGTTTGTTGCTCACCCCCATTACCATGAGCTTCCCCTTTTGCCAGTCTAGGAAAATCCTG AGTTTTTTCTGTGAGACTCCTGCCCTGCTGAAGCTCTCCTGCTCTGACGTCTCCCTCTAT AAGACGCTCATGTACCTGTGCTGCATCCTCATGCTTCTCGCCCCCATCATGGTCATCTCC AGCTCATACACCCTCATCCTGCATCTCATCCACAGGATGAATTCTGCCGCCGGCCACAGG AAGGCCTTGGCCACCTGCTCCTCCCACATGATCATAGTGCTGCTGCTCTTCGGTGCTTCC TTCTACACCTACATGCTCCCGAGTTCCTACCACACAGCTGAGCAGGACATGATGGTGTCT GCCTTTTACACCATCTTCACTCCTGTGCTGAACCCCCTCATTTACAGTCTCCGCAACAAA GATGTCACCAGGGCTCTGAGGAGCATGATGCAGTCAAGAATGAACCAAGAAAAG |
| Conceptual translation |
MCSGNQTSQNQTASTDFTLTGLFAESKHAALLYTVTFLLFLMALTGNALLILLIHSEPRL HTPMYFFISQLALMDLMYLCVTVPKMLVGQVTGDDTISPSGCGIQMFFYLTLAGAEVFLL AAMAYDRYAAVCRPLHYPLLMNQRVCQLLVSACWVLGMVDGLLLTPITMSFPFCQSRKIL SFFCETPALLKLSCSDVSLYKTLMYLCCILMLLAPIMVISSSYTLILHLIHRMNSAAGHR KALATCSSHMIIVLLLFGASFYTYMLPSSYHTAEQDMMVSAFYTIFTPVLNPLIYSLRNK DVTRALRSMMQSRMNQEK Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 248,637,291 | 248,637,291 | NS | G/A | A/T | rs1770109 (DbSNP) |
| 1 | 248,637,367 | 248,637,367 | NS | G/A | R/H | rs1770108 (DbSNP) |
| 1 | 248,637,262 | 248,637,262 | NS | T/C | M/T | rs1770110 (DbSNP) |
| 1 | 248,474,061 | 248,474,061 | SYN | C/T | A/A | 1000GP (CEU) |
| 1 | 100 | -100 | NS | G/A | A/T | 1000GP (YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 248,595,681 | 248,817,382 | CopyNumber | Variation_2359 (DGV) |
| 1 | 248,500,109 | 248,865,374 | CopyNumber | Variation_3340 (DGV) |
| 1 | 248,610,257 | 248,646,763 | CopyNumber | Variation_6817 (DGV) |
| 1 | 248,060,959 | 249,167,690 | CopyNumber | Variation_8354 (DGV) |
| 1 | 248,522,680 | 249,158,239 | CopyNumber | Variation_8355 (DGV) |
| 1 | 248,242,528 | 248,817,382 | CopyNumber | Variation_8935 (DGV) |
| 1 | 248,626,918 | 248,830,541 | Inversion | Variation_37092 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| T202M | M204T | A214T | % Freq | CORP | |
|---|---|---|---|---|---|
| 1 | T | M | A | 95.39 | 0.144 |
| 2 | T | M | T | 1.92 | 0.144 |
| 3 | T | T | T | 1.23 | 0.144 |
| 4 | T | T | A | 0.61 | 0.144 |
| 5 | M | T | T | 0.61 | 0.144 |
| 6 | M | T | A | 0.15 | 0.144 |
| 7 | M | M | A | 0.08 | 0.144 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2T3.aApr07-unspliced | main_exon | CDS | chr1 | 248,473,351 | 248,474,304 | + |
| 3UTR | chr1 | 248,474,304 | 248,474,307 | + | ||