OR2T7 Olfactory Receptor
| Gene Symbol | OR2T71 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | T |
| Pseudogene | No |
| CORP pseudogene probability score | 0.04 (functional) |
| Aliases | OR1-44, HsOR1.5.40P |
| External Ids | HGNC: 15019 GeneBank: AF399480, BK004622, NG_004272 |
| Build #39 labels | OR2T7P |
| Chromosomal location | 1:248,441,207-248,442,130 (+) |
| Cluster | 1@248 |
| Synteny | CLIC#5 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2T27 | 98.62% | 290 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2T27 | 89% | 289 |
| Mouse | Or2t1 | 71% | 288 |
| Rat | Or2t1 | 71% | 286 |
| Cow | OR2T27 | 91% | 286 |
| Orang | OR2T27 | 97% | 290 |
| Horse | OR2T27P | 89% | 290 |
| Horse | OR2T27CP | 88% | 294 |
| Horse | OR2T27HP | 88% | 290 |
| Chimp | OR2T27 | 98% | 290 |
| Chimp | OR2T27BP | 96% | 286 |
Sequence information
| Nucleotide sequence |
ATGCCGACTTTATCCTTCTGGGTTTGTTCAGCAACGCCCGTTTCCCCTGGCTTCTTTGCC CTCATTCTCCTGGTCTTTGTGACCTCCATAGCCAGCAACGTGGTCAAGATCATTCTCATC CACATAGACTCCCGCCTCCACACCCCCATGTACTTCCTGCTCAGCCAGCTCTCCCTCAGG GACATCCTGTATATTTCCACCATTGTGCCCAAAATGCTGGTCGACCAGGTGATGAGCCAG AGAGCCATTTCCTTTGCTGGATGCACTGCCCAACACTTCCTCTACTTGACCTTAGCAGGG GCTGAGTTCTTCCTCCTAGGACTCATGTCCTGTGATCGCTACGTAGCCATCTGCAACCCT CTGCACTATCCTGACCTCATGAGCCGCAAGATCTGCTGGTTGATTGTGGCGGCAGCCTGG CTGGGAGGGTCTATCGATGGTTTCTTGCTCACCCCCGTCACCATGCAGTTCCCCTTCTGT GCCTCTCGGGAGATCAACCACTTCTTCTGCGAGGTGCCTGCCCTTCTGAAGCTCTCCTGC ACGGACACATCAGCCTACGAGACAGCCATGTATGTCTGCTGTATTATGATGCTCCTCATC CCTTTCTCTGTGATCTCGGGCTCTTACACAAGAATTCTCATTACTGTTTATAGGATGAGC GAGGCAGAGGGGAGGCGAAAGGCTGTGGCCACCTGCTCCTCACACATGGTGGTTGTCAGC CTCTTCTATGGGGCTGCCATGTACACATACGTGCTGCCTCATTCTTACCACACCCCTGAG CAGGACAAAGCTGTATCTGCCTTCTACACCATCCTCACTCCCATGCTCAATCCACTCATT TACAGCCTTAGGAACAAGGATGTCACGGGGGCCCTACAGAAGGTTGTTGGGAGGTGTGTG TCCTCAGGAAAGGTAACCACTTTC |
| Conceptual translation |
MPTLSFWVCSATPVSPGFFALILLVFVTSIASNVVKIILIHIDSRLHTPMYFLLSQLSLR DILYISTIVPKMLVDQVMSQRAISFAGCTAQHFLYLTLAGAEFFLLGLMSCDRYVAICNP LHYPDLMSRKICWLIVAAAWLGGSIDGFLLTPVTMQFPFCASREINHFFCEVPALLKLSC TDTSAYETAMYVCCIMMLLIPFSVISGSYTRILITVYRMSEAEGRRKAVATCSSHMVVVS LFYGAAMYTYVLPHSYHTPEQDKAVSAFYTILTPMLNPLIYSLRNKDVTGALQKVVGRCV SSGKVTTF Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 248,604,563 | 248,604,562 | Ins(2) | -/CT | rs58223479 (DbSNP) | |
| 1 | 248,605,316 | 248,605,316 | NS | C/G | T/S | rs73147562 (DbSNP) |
| 1 | 248,604,542 | 248,604,542 | NS | C/T | T/M | rs61834485 (DbSNP) |
| 1 | 248,605,374 | 248,605,374 | SYN | A/G | T/T | rs1339993 (DbSNP) |
| 1 | 248,605,395 | 248,605,395 | SYN | G/T | V/V | rs28631666 (DbSNP) |
| 1 | 248,442,094 | 248,442,094 | SYN | T/G | V/V | 1000GP (CEU) |
| 1 | 100 | -100 | SYN | C/T | Y/Y | 1000GP (YRI, YRI) |
| 1 | 100 | -100 | NS | C/G | T/S | 1000GP (YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 248,595,681 | 248,817,382 | CopyNumber | Variation_2359 (DGV) |
| 1 | 248,500,109 | 248,865,374 | CopyNumber | Variation_3340 (DGV) |
| 1 | 248,060,959 | 249,167,690 | CopyNumber | Variation_8354 (DGV) |
| 1 | 248,522,680 | 249,158,239 | CopyNumber | Variation_8355 (DGV) |
| 1 | 248,242,528 | 248,817,382 | CopyNumber | Variation_8935 (DGV) |
| 1 | 248,604,260 | 248,635,197 | CopyNumber | Variation_71754 (DGV) |
| 1 | 248,604,160 | 248,605,440 | CopyNumber | Variation_71756 (DGV) |
| 1 | 248,604,408 | 248,607,431 | Deletion, CopyNumber | #296 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| C111Y | R113H | D125V | Y217H | M219T | % Freq | CORP | |
|---|---|---|---|---|---|---|---|
| 1 | C | R | D | Y | M | 85.79 | 0.094 |
| 2 | Y | R | D | Y | M | 8.29 | 0.094 |
| 3 | C | R | V | Y | M | 3.69 | 0.094 |
| 4 | Y | R | V | Y | M | 0.92 | 0.094 |
| 5 | C | R | D | Y | T | 0.54 | 0.094 |
| 6 | C | R | D | H | M | 0.38 | 0.094 |
| 7 | C | H | D | Y | M | 0.38 | 0.649 |