OR2V1 Olfactory Receptor
| Gene Symbol | OR2V11 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | V |
| Pseudogene | No |
| CORP pseudogene probability score | 0.03 (functional) |
| Aliases | OR5-4, OST265, HsOR5.4.3 |
| External Ids | HGNC: 8280 GeneBank: AB065465, AF399482, BK004551, NG_004137 |
| Build #39 labels | OR2V1P |
| Chromosomal location | 5:181,124,360-181,125,304 (-) |
| Cluster | 5@181a |
| Synteny | CLIC#11 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2V2 | 87.3% | 315 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2T26 | 61% | 304 |
| Mouse | Or2v1 | 88% | 315 |
| Rat | Or2v1 | 88% | 315 |
| Cow | OR2V2 | 81% | 315 |
| Cow | OR2V2D | 81% | 314 |
| Orang | OR2V1BP | 95% | 315 |
| Orang | OR2V1CP | 96% | 245 |
| Horse | OR2V1C | 83% | 314 |
| Chimp | OR2V2 | 87% | 315 |
Sequence information
| Nucleotide sequence |
ATGGGAAGATGGGTGAACCAGTCCTACACAGATGGCTTCTTCCTCTTGGGCATCTTTTCC CACAGCCAGACTGACCTTGTCCTCTTCTCTGCAGTTATGGTGGTCTTCACAGTGGCCCTC TGTGGGAATGTCCTCCTCATCTTCCTCATCTACCTGGACGCTGGACTTCACACCCCCATG TACTTCTTCCTCAGCCAGCTCTCCCTCATGGACCTCATGTTGGTCTGTAACATTGTGCCA AAGATGGCAGCCAACTTCCTGTCTGGCAGGAAGTCCATCTCCTTTGTGGGCTGTGGCATA CAAATTGGCTTTTTTGTCTCTCTTGTGGGATCTGAGGGGCTCTTGCTGGGACTCATGGCT TATGACCGCTACGTGGCCGTTAGCCACCCACTTCACTATCCCATCCTCATGAATCAGAGG GTCTGTCTCCAGATTACTGGGAGCTCCTGGGCCTTTGGGATAATAGATGGAGTGATTCAG ATGGTGGCAGCCATGGGCTTACCTTACTGTGGCTCAAGGAGCGTGGATCACTTTTTCTGT GAGGTACAAGCTTTATTGAAGCTGGCCTGTGCAGACACTTCCCTTTTTGACACCCTCCTC TTTGCTTGCTGTGTCTTCATGCTTCTCCTTCCCTTCTCCATCATCATGGCCTCCTATGCT TGCATCCTAGGGGCTGTGCTCCGAATACGCTCTGCTCAGGCCTGGAAAAAAGCCCTGGCC ACCTGCTCCTCCCACCTAACAGCTGTCACCCTCTTCTATGGGGCAGCCATGTTCATGTAC CTGAGGCCTAGGCGCTACCGGGCCCCTAGCCATGACAAGGTGGCCTCTATCTTCTACACA GTCCTTACTCCCATGCTGAACCCCCTCATTTACAGCTTGAGGAATGGGGAGGTGATGGGG GCACTGAGGAAGGGGCTGGACCGCTGCAGGATTGGCAGCCAGCAC |
| Conceptual translation |
MGRWVNQSYTDGFFLLGIFSHSQTDLVLFSAVMVVFTVALCGNVLLIFLIYLDAGLHTPM YFFLSQLSLMDLMLVCNIVPKMAANFLSGRKSISFVGCGIQIGFFVSLVGSEGLLLGLMA YDRYVAVSHPLHYPILMNQRVCLQITGSSWAFGIIDGVIQMVAAMGLPYCGSRSVDHFFC EVQALLKLACADTSLFDTLLFACCVFMLLLPFSIIMASYACILGAVLRIRSAQAWKKALA TCSSHLTAVTLFYGAAMFMYLRPRRYRAPSHDKVASIFYTVLTPMLNPLIYSLRNGEVMG ALRKGLDRCRIGSQH Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 5 | 180,551,775 | 180,551,775 | NS | C/T | R/H | rs10035767 (DbSNP) |
| 5 | 180,551,937 | 180,551,937 | NS | C/T | R/H | rs10073017 (DbSNP) |
| 5 | 181,124,937 | 181,124,937 | NS | C/T | R/H | 1000GP (CEU) |
| 5 | 181,124,775 | 181,124,775 | NS | T/C | H/R | 1000GP (CHBJPT) |
| 5 | 100 | -100 | NS | T/C | H/R | 1000GP (YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 5 | 180,433,880 | 180,614,665 | CopyNumber | Variation_29766 (DGV) |
| 5 | 180,433,880 | 180,633,854 | CopyNumber | Variation_53320 (DGV) |
| 5 | 180,545,057 | 180,598,061 | Inversion | Variation_59820 (DGV) |
| 5 | 180,532,601 | 180,598,197 | Inversion | Variation_103362 (DGV) |
| 5 | 180,549,360 | 180,552,404 | CopyNumber | #39 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| H177R | V175A | R123H | F62S | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | H | V | R | F | 82.80 | 0.087 |
| 2 | H | V | H | F | 12.75 | 0.628 |
| 3 | R | V | R | F | 3.69 | 0.128 |
| 4 | H | A | R | F | 0.46 | 0.087 |
| 5 | H | V | R | S | 0.31 | 0.087 |