OR2W1 Olfactory Receptor
| Gene Symbol | OR2W11 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | W |
| Pseudogene | No |
| CORP pseudogene probability score | 0.27 (functional) |
| Aliases | AL035402-B, dJ88J8.1, OR6-13, hs6M1-15, HsOR6.3.2, ORL678 |
| External Ids | HGNC: 8281 GeneBank: AF399628, BK004522, HSA302594-HSA302603, NM_030903 ORDB: ORL678 |
| Build #39 labels | OR2W1 |
| Chromosomal location | 6:29,044,216-29,045,175 (-) |
| Cluster | 6@29 |
| Synteny | CLIC#12 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2G3 | 60% | 305 |
| OR2W4P | 61.31% | 305 |
| OR2W6P | 64.26% | 305 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2AD2 | 62% | 313 |
| Mouse | Or2w1 | 86% | 317 |
| Mouse | Or2w1b | 85% | 317 |
| Rat | Or2w1c | 85% | 317 |
| Rat | Or2w1 | 86% | 310 |
| Cow | OR2W1D | 87% | 317 |
| Orang | OR2W1P | 94% | 316 |
| Horse | OR2W6 | 65% | 305 |
| Chimp | OR2W6 | 65% | 305 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | DB457283 |
| mRNA | BC103872 |
| GNF Atlas2 | 221451_s_at |
Sequence information
| Nucleotide sequence |
ATGGACCAAAGCAATTATAGTTCTTTACATGGTTTTATTCTGCTTGGCTTCTCTAACCAT CCAAAAATGGAGATGATCCTGTCAGGAGTTGTCGCCATCTTCTACTTAATTACATTGGTG GGTAACACAGCCATCATTCTTGCATCTCTCCTGGATTCCCAGCTTCATACACCAATGTAC TTTTTCCTCAGAAATTTATCTTTCCTAGATCTATGTTTCACAACCAGCATCATCCCTCAG ATGCTGGTCAACTTGTGGGGACCTGATAAGACCATCAGCTATGTGGGTTGTATCATCCAA CTCTATGTTTACATGTGGTTGGGCTCAGTTGAGTGCCTTCTCCTGGCTGTTATGTCCTAT GATCGTTTTACAGCTATATGTAAGCCCTTGCATTATTTTGTAGTCATGAACCCACATCTA TGTCTAAAGATGATTATCATGATCTGGAGTATTAGTTTGGCCAATTCTGTAGTATTATGT ACACTCACTCTGAATTTGCCCACATGTGGAAACAACATTCTGGATCATTTCTTGTGTGAG TTGCCAGCTCTGGTCAAGATAGCTTGTGTAGACACCACAACAGTTGAAATGTCTGTTTTC GCTTTAGGCATTATAATTGTCCTCACACCTCTCATCCTTATTCTTATATCCTATGGCTAC ATTGCCAAAGCTGTGCTGAGAACGAAGTCAAAAGCAAGCCAGCGAAAAGCAATGAATACC TGTGGATCTCATCTTACTGTAGTGTCTATGTTCTATGGAACTATTATCTACATGTACCTG CAACCAGGTAACAGGGCTTCCAAAGACCAGGGCAAGTTCCTCACCCTCTTTTACACCGTC ATCACTCCAAGTCTCAACCCGCTCATTTACACCTTAAGAAATAAGGACATGAAGGATGCC CTGAAGAAACTGATGAGATTTCACCACAAATCTACAAAAATAAAGAGGAATTGCAAGTCA |
| Conceptual translation |
MDQSNYSSLHGFILLGFSNHPKMEMILSGVVAIFYLITLVGNTAIILASLLDSQLHTPMY FFLRNLSFLDLCFTTSIIPQMLVNLWGPDKTISYVGCIIQLYVYMWLGSVECLLLAVMSY DRFTAICKPLHYFVVMNPHLCLKMIIMIWSISLANSVVLCTLTLNLPTCGNNILDHFLCE LPALVKIACVDTTTVEMSVFALGIIIVLTPLILILISYGYIAKAVLRTKSKASQRKAMNT CGSHLTVVSMFYGTIIYMYLQPGNRASKDQGKFLTLFYTVITPSLNPLIYTLRNKDMKDA LKKLMRFHHKSTKIKRNCKS Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 6 | 29,012,067 | 29,012,067 | NS | C/T | D/N | rs35771565 (DbSNP) |
| 6 | 29,012,712 | 29,012,712 | NS | C/T | V/M | rs34892006 (DbSNP) |
| 6 | 29,012,116 | 29,012,116 | SYN | A/G | T/T | rs7341218 (DbSNP) |
| 6 | 29,012,068 | 29,012,068 | SYN | C/T | K/K | rs7341215 (DbSNP) |
| 6 | 29,012,059 | 29,012,059 | SYN | C/T | K/K | rs7341214 (DbSNP) |
| 6 | 29,044,290 | 29,044,290 | NS | C/T | D/N | 1000GP (CEU, CHBJPT) |
| 6 | 29,044,339 | 29,044,339 | SYN | G/A | T/T | 1000GP (CEU, CHBJPT) |
| 6 | 100 | -100 | NS | C/T | D/N | 1000GP (YRI, YRI) |
| 6 | 100 | -100 | SYN | G/A | T/T | 1000GP (YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 6 | 29,009,993 | 29,013,052 | CopyNumber | #40 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| D296N | M81V | % Freq | CORP | |
|---|---|---|---|---|
| 1 | D | M | 72.43 | 0.484 |
| 2 | N | M | 23.96 | 0.484 |
| 3 | D | V | 3.61 | 0.484 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2W1.aApr07-unspliced | main_exon | 3UTR | chr6 | 29,044,213 | 29,044,216 | - |
| CDS | chr6 | 29,044,216 | 29,045,175 | - | ||
| 5UTR | chr6 | 29,045,175 | 29,045,240 | - | ||