OR2W5 Olfactory Receptor
| Gene Symbol | OR2W51 (View this gene in GeneCards) |
| Family | 2 |
| Subfamily | W |
| Pseudogene | No |
| CORP pseudogene probability score | 1 (pseudogene) |
| Aliases | HsOR1.5.2P |
| External Ids | HGNC: 15424 GeneBank: AF399492, NM_001004698 |
| Build #39 labels | OR2W5P |
| Chromosomal location | 1:247,491,128-247,492,087 (+) |
| Cluster | 1@248 |
| Synteny | CLIC#5 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR2W6P | 63.59% | 195 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR2W11 | 79% | 203 |
| Mouse | Or2w6 | 64% | 193 |
| Rat | Or2w6 | 63% | 198 |
| Cow | OR2W6 | 63% | 198 |
| Orang | OR2W28 | 92% | 203 |
| Horse | OR2W29 | 84% | 198 |
| Chimp | OR2W6 | 63% | 198 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | CR746895 |
| mRNA | BC137204 |
Sequence information
| Nucleotide sequence |
ATGGGAAAGGACAATGCCAGTTACCTACAGGCATTCATCCTGGTGGGCTCTTCTGATCGG CCTGGACTGGAGAAAATTCTCTTTGCTGTTATCTTGATCTTCTGCATCCTGACCCTGGTG GGCAACACTGCCATCATCCTCTTGCTGGTCATGGATGTCAGGCTCCACACACCCATGTAC TTCTTTCTTGGGAATCTGTCTTTCTTAGATCTCTGCTTTACAGCAAGCATTGCCCCTCAG CTGCTGTGGAACCTGGGGGGTCCAGAGAAGACCATCACCTACCACGGCTGTGTGGCCCAA CTCTACATCTACATGATGCTGGGCTCCACCGAGTGCGTCCTCCTGGTTGTCATGTCCCAT GACCGCTATGTGGCCGTCTGCCGGTCCCTGCACTACATGGCAGTCATGCGCCCACATCTC TGCCTGCAGCTGGTGACTGTGGCCTGGTGCTGTGGCTTCCTAAACTCCTTCATCATGTGT CCTCAGACGATGCAGCTCTCCCGGTGTGGACGTCGCAGGGTGGACCACTTCCTGTGTGAG ATGCCTGCTCTTATTGCCATGTCTTGTGAGGAAACCATGCTGGTAGAAGCGATTCACCTT TGCCCTGGGGGTGGCTCTCCTCCTGGTGCCGCTCTCCCTCATCCTCATCTCCTATGGCGT GATTGCAGCCGCGGTGCTGAGGATGAAGTCAGCAGCAGGGCGAAAGAAAGCCTTCCACAC CTGCTCTTCTCACCTCACAGTGGTCTCTCTCTTCTACGGAACCATCATCTACGTGTACCT GAAGCCGGCCAACAGCTACTCCCAAGATCAGGGGAAGTTCCTGACTCTCTTCTACACCAT CGTCATTCCCAGCATCAACCCCCTCATCTACACTTTGAGGAACAAGGATGTGAAGGGGAC CATGAAGAAACTTCTGGGGTGGGAGAAAGGGGCTGGGGAGCCTCAACGAGGGGAACACTC |
| Conceptual translation |
MGKDNASYLQAFILVGSSDRPGLEKILFAVILIFCILTLVGNTAIILLLVMDVRLHTPMY FFLGNLSFLDLCFTASIAPQLLWNLGGPEKTITYHGCVAQLYIYMMLGSTECVLLVVMSH DRYVAVCRSLHYMAVMRPHLCLQLVTVAWCCGFLNSFIMCPQTMQLSRCGRRRVDHFLCE MPALIAMSCEETMLVEAIHLCPGGGSPPGAALPHPHLLWRDCSRGAEDEVSSRAKESLPH LLFSPHSGLSLLRNHHLRVPEAGQQLLPRSGEVPDSLLHHRHSQHQPPHLHFEEQGCEGD HEETSGVGERGWGASTRGTL Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 1 | 100 | -100 | nonsense SNP | G/T | G/* | 1000GP (YRI) |
| 1 | 100 | -100 | NS | G/A | D/N | 1000GP (YRI, YRI, YRI, YRI) |
| 1 | 100 | -100 | SYN | G/A | L/L | 1000GP (YRI, YRI, YRI) |
| 1 | 247,491,196 | 247,491,196 | SYN | G/A | L/L | 1000GP (CEU, CHBJPT) |
| 1 | 247,491,691 | 247,491,691 | SYN | T/C | S/S | 1000GP (CEU, CHBJPT) |
| 1 | 247,491,900 | 247,491,900 | NS | G/A | R/H | 1000GP (CHBJPT) |
| 1 | 247,491,973 | 247,491,973 | SYN | T/C | H/H | 1000GP (CEU, CHBJPT) |
| 1 | 247,654,498 | 247,654,498 | SYN | A/G | L/L | rs61070846 (DbSNP) |
| 1 | 247,654,993 | 247,654,993 | SYN | C/T | S/S | rs10925061 (DbSNP) |
| 1 | 247,655,051 | 247,655,051 | NS | C/T | P/S | rs71642416 (DbSNP) |
| 1 | 247,655,275 | 247,655,275 | SYN | C/T | H/H | rs12141850 (DbSNP) |
| 1 | 247,655,365 | 247,655,365 | NS | C/G | C/W | rs74152606 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 1 | 247,074,430 | 248,328,835 | CopyNumber | Variation_6816 (DGV) |
| 1 | 247,654,330 | 247,657,389 | Deletion | #181 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| D4N | G22* | D70N | I158N | A183T | G225S | R258H | Q284* | W312C | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | D | G | D | I | A | G | R | Q | W | 91.32 | 1.000 |
| 2 | D | G | D | I | A | G | R | Q | C | 2.84 | 1.000 |
| 3 | D | * | D | I | A | G | R | Q | W | 1.61 | 1.200 |
| 4 | D | G | D | I | T | G | R | Q | C | 1.31 | 1.000 |
| 5 | N | G | D | N | A | G | R | Q | W | 0.84 | 1.000 |
| 6 | D | G | N | I | A | G | R | Q | C | 0.84 | 1.000 |
| 7 | D | G | D | I | A | G | R | * | W | 0.61 | 1.200 |
| 8 | D | G | D | I | A | S | R | Q | W | 0.31 | 1.000 |
| 9 | D | G | D | I | A | G | H | Q | W | 0.15 | 1.000 |
| 10 | D | G | N | I | A | G | R | Q | W | 0.08 | 1.000 |
| 11 | D | G | D | I | T | G | R | Q | W | 0.08 | 1.000 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR2W5.aApr07-unspliced | main_exon | CDS | chr1 | 247,491,128 | 247,492,087 | + |
| 3UTR | chr1 | 247,492,087 | 247,492,409 | + | ||