OR3A2 Olfactory Receptor
| Gene Symbol | OR3A21 (View this gene in GeneCards) |
| Family | 3 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 0.29 (functional) |
| Aliases | OR17-15, OR17-228, OR17-14, HsOR17.1.10, ORL3746, ORL268 |
| External Ids | HGNC: 8283 GeneBank: AF087930, BK004239, HSU04713, NM_002551, U86244 ORDB: ORL3746, ORL268 |
| Build #39 labels | OR3A2 |
| Chromosomal location | 17:3,277,973-3,278,917 (-) |
| Cluster | 17@3b |
| Synteny | CLIC#39 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR3A3 | 90.16% | 315 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR3A1H | 82% | 314 |
| Dog | OR3A1 | 82% | 314 |
| Mouse | Or3a1d | 78% | 314 |
| Rat | Or3a1e | 77% | 313 |
| Cow | OR3A2B | 85% | 315 |
| Orang | OR3A3 | 85% | 315 |
| Horse | OR3A2D | 84% | 315 |
| Horse | OR3A2E | 83% | 315 |
| Horse | OR3A1 | 82% | 314 |
| Chimp | OR3A3 | 84% | 315 |
| Chimp | OR3A1 | 82% | 314 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | DN693319 |
| mRNA | BC095517 |
| GNF Atlas2 | 221386_at |
Sequence information
| Nucleotide sequence |
ATGGAGCCAGAAGCTGGGACCAATAGGACCGCTGTTGCTGAGTTCATTCTACTGGGCCTA GTGCAAACAGAAGAGATGCAGCCAGTTGTCTTTGTGCTCCTCCTCTTTGCCTATCTGGTC ACAACTGGGGGCAACCTCAGCATCCTGGCAGCCGTCTTGGTGGAGCCCAAACTCCACGCC CCCATGTACTTCTTCCTGGGGAACCTGTCAGTGCTGGATGTCGGATGTATCACTGTCACT GTTCCTGCAATGTTGGGTCGTCTCTTGTCCCACAAGTCCACAATTTCCTATGACGCCTGC CTCTCCCAGCTCTTCTTCTTCCACCTTCTGGCTGGGATGGACTGCTTCCTGCTGACCGCC ATGGCCTATGACCGACTCCTGGCCATCTGCCAGCCCCTCACCTACAGCACCCGCATGAGT CAGACAGTCCAGAGGATGTTGGTGGCTGCGTCCTTGGCTTGTGCCTTCACCAACGCACTG ACCCACACTGTGGCCATGTCCACGCTCAACTTCTGTGGCCCCAATGAGGTCAATCACTTC TACTGTGACCTCCCACAGCTCTTCCAGCTCTCCTGCTCCAGCACCCAACTCAATGAGCTG CTGCTCTTTGCTGTGGGTTTCATCATGGCAGGCACACCTTTGGTTCTCATCATCACTGCC TACAGCCACGTGGCAGCTGCAGTTCTACGAATCCGTTCAGTGGAGGGCCGAAAGAAGGCC TTCTCCACGTGTGGCTCCCACCTCACCGTGGTTTGTCTTTTCTTTGGAAGAGGTATCTTC AACTACATGAGACTGGGTTCAGAGGAGGCTTCAGACAAGGATAAAGGGGTTGGAGTTTTC AACACTGTTATCAACCCTATGCTGAACCCTCTTATCTACAGCCTCAGAAACCCTGATGTT CAGGGTGCTCTGTGGCAAATATTTTTGGGGAGGAGATCACTGACC |
| Conceptual translation |
MEPEAGTNRTAVAEFILLGLVQTEEMQPVVFVLLLFAYLVTTGGNLSILAAVLVEPKLHA PMYFFLGNLSVLDVGCITVTVPAMLGRLLSHKSTISYDACLSQLFFFHLLAGMDCFLLTA MAYDRLLAICQPLTYSTRMSQTVQRMLVAASLACAFTNALTHTVAMSTLNFCGPNEVNHF YCDLPQLFQLSCSSTQLNELLLFAVGFIMAGTPLVLIITAYSHVAAAVLRIRSVEGRKKA FSTCGSHLTVVCLFFGRGIFNYMRLGSEEASDKDKGVGVFNTVINPMLNPLIYSLRNPDV QGALWQIFLGRRSLT Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 17 | 100 | -100 | SYN | G/A | H/H | 1000GP (YRI, YRI) |
| 17 | 3,181,284 | 3,181,284 | NS | A/C | W/G | rs61729398 (DbSNP) |
| 17 | 3,181,356 | 3,181,356 | NS | C/G | A/P | rs61742213 (DbSNP) |
| 17 | 3,181,384 | 3,181,384 | SYN | T/C | G/G | rs769434 (DbSNP) |
| 17 | 3,181,555 | 3,181,555 | SYN | A/G | T/T | rs2013809 (DbSNP) |
| 17 | 3,181,644 | 3,181,644 | NS | C/G | V/L | rs61734039 (DbSNP) |
| 17 | 3,181,662 | 3,181,662 | NS | C/G | V/L | rs9901356 (DbSNP) |
| 17 | 3,181,677 | 3,181,677 | NS | C/G | D/H | rs73977611 (DbSNP) |
| 17 | 3,182,087 | 3,182,087 | NS | A/G | I/T | rs62089500 (DbSNP) |
| 17 | 3,277,990 | 3,277,990 | NS | C/A | G/W | 1000GP (CEU) |
| 17 | 3,278,090 | 3,278,090 | SYN | C/T | G/G | 1000GP (CEU, CHBJPT) |
| 17 | 3,278,261 | 3,278,261 | SYN | A/G | T/T | 1000GP (CEU) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 41 (Hasin) | |||
| 17 | 3,179,267 | 3,182,311 | Deletion | #242 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| G316W | P292A | L196V | % Freq | CORP | |
|---|---|---|---|---|---|
| 1 | G | P | L | 94.64 | 0.203 |
| 2 | G | P | V | 3.28 | 0.203 |
| 3 | W | P | L | 1.20 | 0.203 |
| 4 | G | A | L | 0.88 | 0.203 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR3A2.aApr07 | main_exon | 3UTR | chr17 | 3,277,693 | 3,277,973 | - |
| CDS | chr17 | 3,277,973 | 3,278,917 | - | ||
| 5UTR | chr17 | 3,278,917 | 3,278,923 | - | ||
| exon_5UTR | chr17 | 3,279,076 | 3,279,153 | - | ||
| exon_5UTR | chr17 | 3,336,033 | 3,336,126 | - | ||
| exon_5UTR | chr17 | 3,383,804 | 3,383,899 | - | ||
| exon_5UTR | chr17 | 3,386,125 | 3,386,292 | - | ||
| OR3A2.bApr07-unspliced | main_exon | 3UTR | chr17 | 3,277,890 | 3,277,973 | - |
| CDS | chr17 | 3,277,973 | 3,278,917 | - | ||
| 5UTR | chr17 | 3,278,917 | 3,278,974 | - | ||