OR4A16 Olfactory Receptor
| Gene Symbol | OR4A161 (View this gene in GeneCards) |
| Family | 4 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 1 (pseudogene) |
| Aliases | OR11-117, HsOR11.11.3, ORL3439 |
| External Ids | HGNC: 15153 GeneBank: AB065519, BK004249, NM_001005274 ORDB: ORL3439 |
| Build #39 labels | OR4A16 |
| Chromosomal location | 11:55,343,201-55,344,184 (+) |
| Cluster | 11@56 |
| Synteny | CLIC#26 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR4A13P | 73.08% | 312 |
| OR4A1P | 72.96% | 307 |
| OR4A40P | 72.91% | 299 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR4A39 | 74% | 307 |
| Mouse | Or4a39 | 74% | 311 |
| Rat | Or4a69 | 74% | 299 |
| Cow | OR4A2 | 69% | 303 |
| Orang | OR4A47P | 63% | 304 |
| Horse | OR4A142P | 74% | 310 |
| Chimp | OR4A16P | 95% | 320 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC140748 |
Sequence information
| Nucleotide sequence |
ATGAGACCAAGCAGCAATGTTACAGAATTTGTCCTCCTGGGCCTCACTCAAGATCCTGAT GTGAAAAAAACATTATTTGTCATGTTTTTACTCATATACATTGTGACAATGGTGGGAAAC CTCCTCATTTGGGTGACTACTATTGGCAGCCCCTCCTTGGGCTCCCTAATGTACTTCTTC CTTGCCTACTTGTCACTTATGGATGCCATATATTCCACTGCCATGTCACCCAAATTGATG ATAGACTTACTCTGTGATAAAATCGCTATTTCCTTGTCAGCTTGCATGGGTCAGCTCTTC ATAGAACACTTACTTGGTGGTGCAGAGGTCTTCCTTTTGGTGGTGATGGCCTATGATCGC TATGTGGCTATCTCTAAGCCGCTGCACTATTTGAACATCATGAATCGACTGGTTTGCATC CTTCTGTTGGTGGTGGCCATGATTGGAGGTTTTGTGCACTCTGTGGTTCAAATTGTCTTT CTGTACAGTCTACCAATCTGTGGCCCCAATGTTATTGACCACTCTGTCTGTGACATGTAC CCATTGTTGGAACTGTTGTGCCTTGACACCTACTTTATAGGACTCACTGTGGTTGCCAAT GGTGGAATAATTTGTATGGTCATCTTTACCTTTCTGCTAATCTCCTGTGGAGTCATCCTA AACTTCCTTAAAACTTACAGTCAGGAAGAGAGGCATAAAGCCCTGCCTACCTGCATCTCC CACATCATTGTGGTTGCCCTCGTTTTTGTTCCCTGTATTTTTATGTATGTTAGACCCGTT TCCAACTTTCCCTTTGATAAATTAATGACTGTGTTTTATTCAATTATCACACTCATGTTG AATCCTTTAATATACTCGTTGAGACAATCAGAGATGAAAAATGCTATGAAAAATCTCTGG TGTGAAAAGTTAAGTATAGTTAGAAAAAGAGTATCTCCCACACTGAACATATTTATTCCT AGTTCTAAGGCAACAAATAGGCGG |
| Conceptual translation |
MRPSSNVTEFVLLGLTQDPDVKKTLFVMFLLIYIVTMVGNLLIWVTTIGSPSLGSLMYFF LAYLSLMDAIYSTAMSPKLMIDLLCDKIAISLSACMGQLFIEHLLGGAEVFLLVVMAYDR YVAISKPLHYLNIMNRLVCILLLVVAMIGGFVHSVVQIVFLYSLPICGPNVIDHSVCDMY PLLELLCLDTYFIGLTVVANGGIICMVIFTFLLISCGVILNFLKTYSQEERHKALPTCIS HIIVVALVFVPCIFMYVRPVSNFPFDKLMTVFYSIITLMLNPLIYSLRQSEMKNAMKNLW CEKLSIVRKRVSPTLNIFIPSSKATNRR Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 55,111,238 | 55,111,238 | NS | A/C | I/L | rs11229158 (DbSNP) |
| 11 | 55,111,371 | 55,111,371 | NS | A/G | H/R | rs12807769 (DbSNP) |
| 11 | 55,111,584 | 55,111,584 | NS | A/T | K/M | rs10896659 (DbSNP) |
| 11 | 55,111,222 | 55,111,222 | SYN | A/G | L/L | rs7121804 (DbSNP) |
| 11 | 55,343,427 | 55,343,427 | nonsense SNP | C/A | S/* | 1000GP (CEU) |
| 11 | 55,343,696 | 55,343,696 | NS | A/T | I/F | 1000GP (CEU) |
| 11 | 55,344,004 | 55,344,004 | NS | A/C | L/F | 1000GP (CEU) |
| 11 | 55,344,126 | 55,344,126 | NS | A/T | K/I | 1000GP (CEU) |
| 11 | 55,343,762 | 55,343,762 | NS | C/A | L/I | 1000GP (CEU, CHBJPT) |
| 11 | 55,343,401 | 55,343,401 | NS | G/A | M/I | 1000GP (CEU) |
| 11 | 55,343,239 | 55,343,239 | SYN | G/A | L/L | 1000GP (CEU) |
| 11 | 55,343,746 | 55,343,746 | SYN | G/A | L/L | 1000GP (CEU) |
| 11 | 55,344,131 | 55,344,131 | NS | G/T | V/L | 1000GP (CEU) |
| 11 | 55,344,108 | 55,344,108 | NS | A/T | K/M | 1000GP (CEU, CHBJPT) |
| 11 | 55,344,033 | 55,344,033 | NS | T/C | L/P | 1000GP (CEU) |
| 11 | 55,343,977 | 55,343,977 | SYN | C/T | P/P | 1000GP (CEU) |
| 11 | 55,343,212 | 55,343,212 | SYN | C/T | S/S | 1000GP (CEU) |
| 11 | 55,344,024 | 55,344,024 | NS | T/C | I/T | 1000GP (CEU) |
| 11 | 55,344,020 | 55,344,020 | NS | T/A | S/T | 1000GP (CEU) |
| 11 | 55,343,681 | 55,343,681 | NS | C/G | L/V | 1000GP (CEU) |
| 11 | 55,343,389 | 55,343,389 | SYN | C/T | Y/Y | 1000GP (CEU) |
| 11 | 100 | -100 | NS | C/G | L/V | 1000GP (YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 54,835,623 | 55,879,426 | CopyNumber | Variation_8690 (DGV) |
| 11 | 55,083,434 | 55,156,434 | CopyNumber | Variation_48825 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| M67I | S76* | L105V | L161V | I166F | L188I | L268F | S274T | I275T | K303M | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | M | S | L | L | I | L | L | S | I | K | 50.38 | 1.000 |
| 2 | M | S | L | L | I | I | L | S | I | M | 43.78 | 1.000 |
| 3 | M | S | L | L | I | L | L | S | T | K | 1.23 | 1.000 |
| 4 | M | S | V | L | I | L | L | S | I | K | 1.00 | 1.000 |
| 5 | M | S | L | V | F | L | F | T | I | K | 0.61 | 1.000 |
| 6 | I | * | L | V | F | L | F | S | I | K | 0.54 | 1.200 |
| 7 | M | S | L | V | F | L | L | S | I | K | 0.46 | 1.000 |
| 8 | M | S | L | L | I | I | L | S | I | K | 0.31 | 1.000 |
| 9 | I | * | L | V | F | L | F | T | I | K | 0.31 | 1.200 |
| 10 | M | S | L | V | F | L | F | S | I | K | 0.31 | 1.000 |
| 11 | I | * | L | V | I | L | L | S | I | K | 0.23 | 1.200 |
| 12 | I | S | L | V | F | L | F | T | I | K | 0.15 | 1.000 |
| 13 | I | * | L | V | F | L | L | S | I | K | 0.15 | 1.200 |
| 14 | M | S | L | L | I | L | L | S | I | M | 0.15 | 1.000 |
| 15 | M | * | L | V | F | L | F | T | I | K | 0.08 | 1.200 |
| 16 | I | S | L | L | I | I | L | S | I | M | 0.08 | 1.000 |
| 17 | M | S | L | V | I | L | L | S | I | K | 0.08 | 1.000 |
| 18 | I | * | L | L | I | L | F | S | I | K | 0.08 | 1.200 |
| 19 | M | S | L | L | I | L | F | S | I | K | 0.08 | 1.000 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR4A16.aApr07-unspliced | main_exon | CDS | chr11 | 55,343,201 | 55,344,184 | + |
| 3UTR | chr11 | 55,344,184 | 55,344,187 | + | ||