OR4A47 Olfactory Receptor
| Gene Symbol | OR4A471 (View this gene in GeneCards) |
| Family | 4 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 0.18 (functional) |
| Aliases | OR11-113, HsOR11.8.13 |
| External Ids | HGNC: 31266 GeneBank: BK004380, NM_001005512 |
| Build #39 labels | |
| Chromosomal location | 11:48,488,793-48,489,719 (+) |
| Cluster | 11@48 |
| Synteny | CLIC#26 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR4A19P | 90.61% | 309 |
| OR4A4P | 93.85% | 309 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR4A47FP | 85% | 308 |
| Dog | OR4A47C | 84% | 308 |
| Dog | OR4A47D | 82% | 308 |
| Mouse | Or4a47 | 81% | 306 |
| Rat | Or4a47 | 81% | 307 |
| Cow | OR4A47D | 79% | 306 |
| Orang | OR4A47P | 95% | 309 |
| Horse | OR4A47L | 84% | 303 |
| Horse | OR4A47K | 82% | 308 |
| Horse | OR4A47M | 82% | 303 |
| Chimp | OR4A47H | 96% | 299 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC140738 |
Sequence information
| Nucleotide sequence |
ATGGAGCCAAGGAAAAATGTGACTGACTTTGTCCTCTTGGGCTTCACACAGAATCCAAAG GAGCAGAAAGTACTTTTTGTTATGTTCTTGCTCTTCTACATTTTGACCATGGTGGGCAAC CTGCTCATTGTAGTGACCGTAACTGTCAGTGAGACCCTGGGCTCACCAATGTACTTCTTT CTTGCTGGCTTATCATTTATAGATATCATTTATTCTTCATCCATTTCCCCCAGATTGATT TCAGGCTTGTTCTTTGGGAATAATTCCATATCCTTCCAATCTTGCATGGCCCAGCTCTTT ATCGAGCACATTTTCGGTGGGTCAGAGGTCTTTCTCCTGTTGGTGATGGCCTATGACTGC TATGTGGCCATCTGTAAGCCCTTGCATTATTTGGTTATCATGAGACAATGGGTGTGTGTT GTGCTGCTGGTAGTGTCCTGGGTTGGAGGATTTCTGCACTCAGTATTTCAACTTAGCATT ATTTATGGGCTCCCATTCTGTGGCCCCAATGTCATTGATCATTTTTTCTGTGACATGTAT CCCTTATTGAAACTGGTCTGCACTGACACCCATGCTATTGGCCTCTTAGTGGTGGCCAAT GGAGGACTGGCTTGCACTATTGTGTTTCTGCTCTTACTCATCTCTTATGGTGTCATCTTG CACTCTTTAAAGAACCTTAGTCAGAAAGGGAGGCAAAAAGCCCTCTCAACCTGCAGTTCC CACATGACTGTGGTTGTCTTCTTCTTTGTTCCTTGTATTTTTATGTATGCTAGACCTGCT AGGACCTTCCCCATTGACAAATCAGTGAGTGTGTTTTATACAGTCATAACCCCAATGCTG AACCCCTTAATCTACACTCTGAGAAATTCTGAGATGACAAGTGCTATGAAGAAGCTCTGG AGAAGAGACCTCATATCAAGTAGTACA |
| Conceptual translation |
MEPRKNVTDFVLLGFTQNPKEQKVLFVMFLLFYILTMVGNLLIVVTVTVSETLGSPMYFF LAGLSFIDIIYSSSISPRLISGLFFGNNSISFQSCMAQLFIEHIFGGSEVFLLLVMAYDC YVAICKPLHYLVIMRQWVCVVLLVVSWVGGFLHSVFQLSIIYGLPFCGPNVIDHFFCDMY PLLKLVCTDTHAIGLLVVANGGLACTIVFLLLLISYGVILHSLKNLSQKGRQKALSTCSS HMTVVVFFFVPCIFMYARPARTFPIDKSVSVFYTVITPMLNPLIYTLRNSEMTSAMKKLW RRDLISSST Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | A/C | I/L | 1000GP (YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | T/C | Y/Y | 1000GP (YRI, YRI) |
| 11 | 48,489,146 | 48,489,146 | SYN | T/C | Y/Y | 1000GP (CHBJPT) |
| 11 | 48,489,498 | 48,489,498 | NS | T/C | S/P | 1000GP (CEU) |
| 11 | 48,510,517 | 48,510,517 | NS | A/C | Y/S | rs12805127 (DbSNP) |
| 11 | 48,510,537 | 48,510,537 | NS | A/T | T/S | rs12806692 (DbSNP) |
| 11 | 48,510,589 | 48,510,589 | NS | A/G | D/G | rs12805819 (DbSNP) |
| 11 | 48,510,628 | 48,510,628 | NS | G/T | C/F | rs12805853 (DbSNP) |
| 11 | 48,510,654 | 48,510,654 | NS | A/C | I/L | rs7103557 (DbSNP) |
| 11 | 48,510,777 | 48,510,777 | NS | A/G | M/V | rs7103992 (DbSNP) |
| 11 | 48,510,919 | 48,510,919 | NS | A/C | D/A | rs7103932 (DbSNP) |
| 11 | 48,511,037 | 48,511,037 | SYN | A/G | R/R | rs7479221 (DbSNP) |
| 11 | 48,511,054 | 48,511,054 | NS | A/C | N/T | rs73464794 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 48,303,671 | 48,863,606 | CopyNumber | Variation_3848 (DGV) |
| 11 | 48,346,202 | 48,972,502 | CopyNumber | Variation_9183 (DGV) |
| 11 | 48,365,757 | 49,068,634 | CopyNumber | Variation_2922 (DGV) |
| 11 | 48,479,497 | 48,689,328 | CopyNumber | Variation_5013 (DGV) |
| 11 | 48,510,245 | 48,513,271 | Deletion, CopyNumber | #281 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| G54D | Y58S | G82D | C95F | I104L | V141L | V145M | A192D | A234V | S236P | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | G | Y | G | C | L | V | M | A | A | S | 49.46 | 0.400 |
| 2 | G | Y | G | C | I | V | V | A | A | S | 45.39 | 0.400 |
| 3 | G | Y | G | C | L | V | M | D | A | S | 1.15 | 0.400 |
| 4 | G | Y | G | C | L | V | M | A | A | P | 0.84 | 0.512 |
| 5 | D | Y | G | C | L | V | M | A | A | S | 0.61 | 0.400 |
| 6 | G | Y | G | C | I | V | M | A | A | S | 0.46 | 0.400 |
| 7 | G | Y | G | C | I | V | V | A | V | S | 0.38 | 0.656 |
| 8 | G | Y | D | C | I | L | V | A | A | S | 0.23 | 0.400 |
| 9 | G | Y | D | C | L | L | V | A | A | S | 0.23 | 0.400 |
| 10 | G | Y | G | C | L | V | V | A | A | S | 0.15 | 0.400 |
| 11 | G | Y | G | C | L | L | M | A | A | S | 0.15 | 0.400 |
| 12 | G | Y | G | C | I | L | V | A | A | S | 0.08 | 0.400 |
| 13 | G | S | D | F | L | V | M | A | A | S | 0.08 | 0.999 |
| 14 | G | S | G | C | L | L | V | A | A | S | 0.08 | 0.910 |
| 15 | G | S | D | C | I | L | V | A | A | S | 0.08 | 0.910 |
| 16 | G | S | G | C | L | L | M | A | A | S | 0.08 | 0.910 |
| 17 | G | Y | D | C | I | V | V | A | A | S | 0.08 | 0.400 |
| 18 | G | S | D | F | L | L | V | A | A | S | 0.08 | 0.999 |
| 19 | G | S | G | C | L | V | M | A | A | S | 0.08 | 0.910 |
| 20 | G | Y | D | F | L | V | M | A | A | S | 0.08 | 0.982 |
| 21 | G | S | D | F | L | L | M | A | A | S | 0.08 | 0.999 |
| 22 | G | Y | G | C | L | L | V | A | A | S | 0.08 | 0.400 |
| 23 | G | Y | G | F | L | L | V | A | A | S | 0.08 | 0.982 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR4A47.aApr07-unspliced | main_exon | CDS | chr11 | 48,488,793 | 48,489,719 | + |
| 3UTR | chr11 | 48,489,719 | 48,489,722 | + | ||