OR4A50P Olfactory Receptor
| Gene Symbol | OR4A50P1 (View this gene in GeneCards) |
| Family | 4 |
| Subfamily | A |
| Pseudogene | Yes |
| CORP pseudogene probability score | |
| Aliases | OR11-121, HsOR11.11.10P |
| External Ids | HGNC: 31269 GeneBank: BK004800, NG_004420 |
| Build #39 labels | |
| Chromosomal location | 11:55,475,943-55,476,428 (+) |
| Cluster | 11@56 |
| Synteny | CLIC#26 |
| Remarks | Disrupted by Line repeat |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR4A16 | 74.84% | 155 |
| OR4A17P | 76.92% | 156 |
| OR4A1P | 73.08% | 156 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR4A39 | 74% | 153 |
| Mouse | Or4a39 | 73% | 154 |
| Rat | Or4a77c | 71% | 155 |
| Cow | OR4A15P | 64% | 155 |
| Orang | OR4A47P | 58% | 156 |
| Horse | OR4A142P | 75% | 155 |
| Chimp | OR4A17P | 84% | 159 |
Sequence information
| Nucleotide sequence |
ATGGGATCTAGTAACAATGTTACAGAATTTGTCCTCCTGGCCCTCACTCAGGCTCCTGAT GTGCAAAAAGTATTATTTGTAATGTTTTTATTCACATACATTGTGACTATGGTGGGCAAC CTGCTCACTGTGGTGACCATTTTTGCCCTCCCTCTTTGGGCTCCCTAGTGTAACTCTTCC TTGCCTGCCTGTCATTGATGGATGCCGTATATTCCACTTCATTTTCTCCTAAACTGATGA TAGACTTACTCTGCGATAAAAAAGACTGTTTCCTTCCCGGCTTGCATGGGCCAGCTATTT GCGGACCACCTATTTGGTGGTGTTGAGGTCTTTCTTTTCGTGGGGATGGCCTATGATCAC TATGTGGCCATCTCTAAGCCACTGCACTATTTGATCATCGTGAATCGACTGGTTTGCATC CTTCTGTTGGTGGTGGCCGTGACTGGAGGATTTTGAATTCTATGTTTCTTTTTTTTTAAT TTATTT |
| Conceptual translation |
MGSSNNVTEFVLLALTQAPDVQKVLFVMFLFTYIVTMVGNLLTVVTIFA/PSLGSLVX FLACLSLMDAVYSTSFSPKLMIDLLCDKK\VSFPACMGQLFADHLFGGVEVFLFVGMAY DHYVAISKPLHYLIIVNRLVCILLLVVAVTGGFXHSMFLFF Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 55,243,898 | 55,243,897 | Ins(1) | -/A | rs71055506 (DbSNP) | |
| 11 | 55,243,899 | 55,243,898 | Ins(1) | -/A | rs72101747 (DbSNP) | |
| 11 | 55,243,896 | 55,243,895 | Ins(1) | -/T | rs60129385 (DbSNP) | |
| 11 | 55,243,887 | 55,243,886 | Ins(1) | -/T | rs5791947 (DbSNP) | |
| 11 | 55,243,888 | 55,243,887 | Ins(1) | -/T | rs67746866 (DbSNP) | |
| 11 | 55,243,895 | 55,243,895 | SNP | A/T | rs71457923 (DbSNP), rs34448286 (DbSNP) | |
| 11 | 55,243,632 | 55,243,632 | SNP | C/G | rs1783718 (DbSNP) | |
| 11 | 55,243,584 | 55,243,584 | SNP | C/T | rs557508 (DbSNP) | |
| 11 | 55,243,696 | 55,243,696 | SNP | C/T | rs61917999 (DbSNP) | |
| 11 | 55,243,896 | 55,243,896 | SNP | T/A | rs1783717 (DbSNP) | |
| 11 | 55,476,108 | 55,476,108 | SNP | T/C | 1000GP (CEU, CHBJPT) | |
| 11 | 55,476,156 | 55,476,156 | SNP | C/G | 1000GP (CEU, CHBJPT) | |
| 11 | 55,476,220 | 55,476,220 | SNP | C/T | 1000GP (CEU) | |
| 11 | 55,476,419 | 55,476,419 | SNP | T/A | 1000GP (CEU) | |
| 11 | 100 | -100 | SNP | T/C | 1000GP (YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 55,153,930 | 55,816,828 | CopyNumber | Variation_0308 (DGV) |
| 11 | 55,222,420 | 55,621,884 | CopyNumber | Variation_3852 (DGV) |
| 11 | 55,183,726 | 55,258,691 | CopyNumber | Variation_6922 (DGV) |
| 11 | 54,835,623 | 55,879,426 | CopyNumber | Variation_8690 (DGV) |
| 11 | 55,121,706 | 55,340,753 | CopyNumber | Variation_9185 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.