OR4C12 Olfactory Receptor
| Gene Symbol | OR4C121 (View this gene in GeneCards) |
| Family | 4 |
| Subfamily | C |
| Pseudogene | No |
| CORP pseudogene probability score | 0.18 (functional) |
| Aliases | OR11-259, HsOR11.9.5, ORL3335 |
| External Ids | HGNC: 15168 GeneBank: AF399576, BK004413, NM_001005270 ORDB: ORL3335 |
| Build #39 labels | OR4C12 |
| Chromosomal location | 11:49,981,575-49,982,501 (-) |
| Cluster | 11@50 |
| Synteny | CLIC#26 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR4C2P | 88.35% | 309 |
| OR4C50P | 86.08% | 309 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR4C12C | 84% | 309 |
| Mouse | Or4c12 | 84% | 309 |
| Mouse | Or4c12b | 83% | 304 |
| Rat | Or4c12 | 84% | 303 |
| Rat | Or4c12b-ps | 83% | 302 |
| Cow | OR4C12EP | 78% | 303 |
| Orang | OR4C9P | 66% | 307 |
| Horse | OR4C2 | 81% | 305 |
| Chimp | OR4C2P | 89% | 308 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136851 |
| GNF Atlas2 | gnf1h02093_s_at |
Sequence information
| Nucleotide sequence |
ATGGAGAAGAAAAAGAATGTGACTGAATTCATTTTAATAGGTCTTACACAGAACCCCATA ATGGAGAAAGTCACGTTTGTAGTATTTTTGGTTCTTTACATGATAACACTTTCAGGCAAC CTGCTCATTGTGGTTACCATTACCACCAGCCAGGCTCTGAGCTCCCCCATGTACTTCTTC CTGACCCACCTTTCTTTGATAGACACAGTTTATTCTTCTTCTTCAGCTCCTAAGTTGATT GTGGATTCCTTTCAAGAGAAGAAAATCATCTCCTTTAATGGGTGTATGGCTCAAGCCTAT GCAGAACACATTTTTGGTGCTACTGAGATCATCCTGCTGACAGTGATGGCCTGTGACTGC TATGTGGCCATCTGCAAACCTCTGAACTACACAACCATTATGAGCCACAGCCTGTGCATT CTCCTGGTGGCAGTGGCCTGGGTGGGAGGATTTCTTCATGCAACTATTCAGATTCTCTTT ACAGTATGGCTGCCCTTCTGTGGCCCCAATGTCATAGGCCACTTCATGTGTGACTTGTAC CCATTGTTAAAACTTGTTTGCATAGACACTCATACCCTTGGTCTCTTTGTTGCTGTGAAC AGTGGGTTTATCTGCTTATTAAACTTCCTTATCTTGGTGGTATCCTATGTGATCATCTTG AGATCTTTAAAGAACAATAGCTTGGAGGGGAGGTGTAAAGCCCTCTCCACCTGTATTTCT CACATCATAGTAGTTGTCTTATTCTTTGTGCCCTGTATATTTGTGTATCTGCGCTCAGTG ACCACTCTGCCCATTGATAAAGCTGTTGCTGTATTTTATACTATGGTGGTCCCAATGTTA AATCCCGTGGTCTACACACTCAGAAATGCTGAGGTAAAAAGTGCAATAAGGAAGCTTTGG AGAAAAAAAGTGACTTCAGATAATGAT |
| Conceptual translation |
MEKKKNVTEFILIGLTQNPIMEKVTFVVFLVLYMITLSGNLLIVVTITTSQALSSPMYFF LTHLSLIDTVYSSSSAPKLIVDSFQEKKIISFNGCMAQAYAEHIFGATEIILLTVMACDC YVAICKPLNYTTIMSHSLCILLVAVAWVGGFLHATIQILFTVWLPFCGPNVIGHFMCDLY PLLKLVCIDTHTLGLFVAVNSGFICLLNFLILVVSYVIILRSLKNNSLEGRCKALSTCIS HIIVVVLFFVPCIFVYLRSVTTLPIDKAVAVFYTMVVPMLNPVVYTLRNAEVKSAIRKLW RKKVTSDND Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | C/A | V/L | 1000GP (YRI, YRI) |
| 11 | 49,981,655 | 49,981,655 | NS | C/A | V/L | 1000GP (CEU, CHBJPT) |
| 11 | 50,003,191 | 50,003,191 | NS | C/A | V/L | rs4598671 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 49,732,291 | 50,117,547 | CopyNumber | Variation_6919 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| V283L | V269L | R258C | T190I | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | L | V | R | T | 49.85 | 0.400 |
| 2 | V | V | R | T | 49.62 | 0.400 |
| 3 | L | V | C | T | 0.31 | 0.400 |
| 4 | V | V | R | I | 0.15 | 0.400 |
| 5 | V | L | R | T | 0.08 | 0.400 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR4C12.aApr07-unspliced | main_exon | 3UTR | chr11 | 49,981,572 | 49,981,575 | - |
| CDS | chr11 | 49,981,575 | 49,982,501 | - | ||