OR4D1 Olfactory Receptor
| Gene Symbol | OR4D11 (View this gene in GeneCards) |
| Family | 4 |
| Subfamily | D |
| Pseudogene | No |
| CORP pseudogene probability score | 0.05 (functional) |
| Aliases | OR17-23, AC005962-A, HSTPCR16, HsOR17.2.1, ORL207 |
| External Ids | HGNC: 8293 GeneBank: AB065913, AF399567, BK004544, HSTPCR16P, NM_012374 ORDB: ORL207 |
| Build #39 labels | OR4D1 |
| Chromosomal location | 17:58,155,154-58,156,083 (+) |
| Cluster | 17@56 |
| Synteny | CLIC#40 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR4D2 | 79.87% | 303 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR4D2C | 83% | 310 |
| Dog | OR4D2 | 82% | 310 |
| Mouse | Or4d1 | 86% | 310 |
| Rat | Or4d2 | 81% | 311 |
| Cow | OR4D1B | 84% | 311 |
| Cow | OR4D2D | 83% | 310 |
| Orang | OR4D2P | 79% | 303 |
| Horse | OR4D1CP | 85% | 310 |
| Chimp | OR4D2P | 80% | 303 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | X89670 |
| GNF Atlas2 | gnf1h05923_at |
Sequence information
| Nucleotide sequence |
ATGGAACCACAGAACACCACACAGGTATCAATGTTTGTCCTCTTAGGGTTTTCACAGACC CAAGAGCTCCAGAAATTCCTGTTCCTTCTGTTCCTGTTAGTCTATGTTACCACCATTGTG GGAAACCTCCTTATCATGGTCACAGTGACTTTTGACTGCCGGCTCCACACACCCATGTAT TTTCTGCTCCGAAATCTAGCTCTCATAGACCTCTGCTATTCCACAGTCACCTCTCCAAAG ATGCTGGTGGACTTCCTCCATGAGACCAAGACGATCTCCTACCAGGGCTGCATGGCCCAG ATCTTCTTCTTCCACCTTTTGGGAGGTGGGACTGTCTTTTTTCTCTCAGTCATGGCCTAT GACCGCTACATAGCCATCTCCCAGCCCCTCCGGTATGTCACCATCATGAACACTCAATTG TGTGTGGGCCTGGTAGTAGCCGCCTGGGTGGGGGGCTTTGTCCACTCCATTGTCCAACTG GCTCTGATACTTCCACTGCCCTTCTGTGGCCCCAATATCCTAGATAACTTCTACTGTGAT GTTCCCCAAGTACTGAGACTTGCCTGCACTGATACCTCCCTCCTGGAGTTCCTCATGATC TCCAACAGTGGGCTGCTAGTTATCATCTGGTTCCTCCTCCTTCTGATCTCTTATACTGTC ATCCTGGTGATGCTGAGGTCCCACTCGGGAAAGGCAAGGAGGAAGGCAGCTTCCACCTGC ACCACCCACATCATCGTGGTGTCCATGATCTTCATTCCCTGTATCTATATCTATACCTGG CCCTTCACCCCATTCCTCATGGACAAGGCTGTGTCCATCAGCTACACAGTCATGACCCCC ATGCTCAACCCCATGATCTACACCCTGAGAAACCAGGACATGAAAGCAGCCATGAGGAGA TTAGGCAAGTGCCTAGTAATTTGCAGGGAG |
| Conceptual translation |
MEPQNTTQVSMFVLLGFSQTQELQKFLFLLFLLVYVTTIVGNLLIMVTVTFDCRLHTPMY FLLRNLALIDLCYSTVTSPKMLVDFLHETKTISYQGCMAQIFFFHLLGGGTVFFLSVMAY DRYIAISQPLRYVTIMNTQLCVGLVVAAWVGGFVHSIVQLALILPLPFCGPNILDNFYCD VPQVLRLACTDTSLLEFLMISNSGLLVIIWFLLLLISYTVILVMLRSHSGKARRKAASTC TTHIIVVSMIFIPCIYIYTWPFTPFLMDKAVSISYTVMTPMLNPMIYTLRNQDMKAAMRR LGKCLVICRE Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 17 | 100 | -100 | NS | G/A | R/Q | 1000GP (YRI, YRI, YRI, YRI) |
| 17 | 56,232,675 | 56,232,675 | NS | A/G | Q/R | rs12602205 (DbSNP) |
| 17 | 56,232,787 | 56,232,787 | SYN | C/G | T/T | rs17222013 (DbSNP) |
| 17 | 56,232,977 | 56,232,977 | NS | C/T | H/Y | rs62636636 (DbSNP) |
| 17 | 56,233,034 | 56,233,034 | NS | A/C | I/L | rs7218964 (DbSNP) |
| 17 | 56,233,132 | 56,233,132 | SYN | A/G | L/L | rs17822299 (DbSNP) |
| 17 | 56,233,164 | 56,233,164 | NS | C/T | S/F | rs28602491 (DbSNP) |
| 17 | 56,233,168 | 56,233,168 | nonsense SNP | A/T | */Y | rs71372828 (DbSNP) |
| 17 | 56,233,234 | 56,233,234 | SYN | C/T | C/C | rs62636635 (DbSNP) |
| 17 | 58,155,258 | 58,155,258 | SYN | T/C | Y/Y | 1000GP (CEU) |
| 17 | 58,155,314 | 58,155,314 | NS | G/A | R/Q | 1000GP (CEU) |
| 17 | 58,155,673 | 58,155,673 | NS | C/A | L/I | 1000GP (CEU, CHBJPT) |
| 17 | 58,155,873 | 58,155,873 | SYN | C/T | C/C | 1000GP (CEU) |
| 17 | 58,155,892 | 58,155,892 | NS | G/A | V/M | 1000GP (CEU) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 241 (Hasin) | |||
| 17 | 56,232,346 | 56,232,526 | Del(-15) | #25(modil) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| I69V | Y120C | P129T | H155Y | L174I | S217F | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|
| 1 | I | Y | P | H | L | S | 74.73 | 0.075 |
| 2 | I | Y | P | H | I | S | 23.20 | 0.075 |
| 3 | I | Y | P | H | L | F | 0.69 | 0.194 |
| 4 | I | Y | P | Y | L | S | 0.69 | 0.075 |
| 5 | I | C | P | H | L | S | 0.46 | 0.075 |
| 6 | V | Y | P | H | L | S | 0.08 | 0.075 |
| 7 | V | Y | P | H | I | S | 0.08 | 0.075 |
| 8 | I | Y | T | H | L | S | 0.08 | 0.147 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR4D1.aApr07-unspliced | main_exon | CDS | chr17 | 58,155,154 | 58,156,083 | + |
| 3UTR | chr17 | 58,156,083 | 58,156,086 | + | ||