OR4F6 Olfactory Receptor
| Gene Symbol | OR4F61 (View this gene in GeneCards) |
| Family | 4 |
| Subfamily | F |
| Pseudogene | No |
| CORP pseudogene probability score | 0.84 (pseudogene) |
| Aliases | OR15-15, HsOR15.2.1 |
| External Ids | HGNC: 15372 GeneBank: AB065899, AF282018, BK004367, NM_001005326 |
| Build #39 labels | OR4F6 |
| Chromosomal location | 15:101,805,720-101,806,655 (+) |
| Cluster | 15@102 |
| Synteny | CLIC#32 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR4F13P | 69.03% | 310 |
| OR4F14P | 72.73% | 308 |
| OR4F15 | 70.74% | 311 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR4F25 | 70% | 311 |
| Mouse | Or4f6 | 85% | 311 |
| Rat | Or4f6 | 84% | 311 |
| Cow | OR4F58B | 77% | 311 |
| Orang | OR4F6P | 95% | 311 |
| Horse | OR4F6EP | 82% | 311 |
| Horse | OR4F6C | 81% | 311 |
| Horse | OR4F6DP | 80% | 311 |
| Chimp | OR4F14 | 72% | 311 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC137003 |
| GNF Atlas2 | gnf1h10878_at |
Sequence information
| Nucleotide sequence |
ATGGATGAAGCCAATCACTCTGTGGTCTCTGAGTTTGTGTTCCTGGGACTCTCTGACTCG CGGAAGATCCAGCTCCTCCTCTTCCTCTTTTTCTCAGTGTTCTATGTGTCAAGCCTGATG GGAAATCTCCTCATTGTGCTAACTGTGACCTCTGACCCTCGTTTACAGTCCCCCATGTAC TTCCTGCTGGCCAACCTTTCCATCATCAATTTGGTATTTTGTTCCTCCACAGCTCCCAAG ATGATTTATGACCTTTTCAGGAAGCACAAGACCATCTCTTTTGGGGGCTGTGTAGTTCAG ATCTTCTTTATCCATGCAGTTGGGGGAACTGAGATGGTGCTGCTCATAGCCATGGCTTTT GACCGATATGTGGCCATATGTAAGCCTCTCCACTACCTGACCATCATGAACCCACAAAGG TGCATTTTGTTTTTAGTCATTTCCTGGATTATAGGTATTATTCACTCAGTGATTCAGTTG GCTTTTGTTGTAGACCTGCTGTTCTGTGGCCCTAATGAATTAGATAGTTTCTTTTGTGAT CTTCCTCGATTTATCAAACTGGCTTGCATAGAGACCTACACATTGGGATTCATGGTTACT GCCAATAGTGGATTTATTTCTCTGGCTTCTTTTTTAATTCTCATAATCTCTTACATCTTT ATTTTGGTGACTGTTCAGAAAAAATCTTCAGGTGGTATATTCAAGGCTTTCTCTATGCTG TCAGCTCATGTCATTGTGGTGGTTTTGGTCTTTGGGCCATTAATCTTTTTCTATATTTTT CCATTTCCCACATCACATCTTGATAAATTCCTTGCCATCTTTGATGCAGTTATCACTCCC GTTTTGAATCCAGTCATCTATACTTTTAGAAATAAAGAGATGATGGTGGCAATGAGAAGA CGATGCTCTCAGTTTGTGAATTACAGTAAAATCTTT |
| Conceptual translation |
MDEANHSVVSEFVFLGLSDSRKIQLLLFLFFSVFYVSSLMGNLLIVLTVTSDPRLQSPMY FLLANLSIINLVFCSSTAPKMIYDLFRKHKTISFGGCVVQIFFIHAVGGTEMVLLIAMAF DRYVAICKPLHYLTIMNPQRCILFLVISWIIGIIHSVIQLAFVVDLLFCGPNELDSFFCD LPRFIKLACIETYTLGFMVTANSGFISLASFLILIISYIFILVTVQKKSSGGIFKAFSML SAHVIVVVLVFGPLIFFYIFPFPTSHLDKFLAIFDAVITPVLNPVIYTFRNKEMMVAMRR RCSQFVNYSKIF Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 15 | 100 | -100 | NS | A/G | K/E | 1000GP (YRI, YRI) |
| 15 | 100 | -100 | SYN | G/A | V/V | 1000GP (YRI, YRI) |
| 15 | 101,805,880 | 101,805,880 | NS | G/A | R/H | 1000GP (CEU) |
| 15 | 101,806,140 | 101,806,140 | NS | T/G | C/G | 1000GP (CHBJPT) |
| 15 | 102,346,030 | 102,346,030 | SYN | A/G | V/V | rs401632 (DbSNP) |
| 15 | 102,346,083 | 102,346,083 | NS | A/G | H/R | rs61746768 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 15 | 101,991,277 | 102,393,237 | CopyNumber | Variation_34506 (DGV) |
| 15 | 102,036,377 | 102,393,237 | CopyNumber | Variation_8808 (DGV) |
| 15 | 102,197,455 | 102,352,490 | CopyNumber | Variation_0193 (DGV) |
| 15 | 102,271,630 | 102,431,074 | CopyNumber | Variation_3985 (DGV) |
| 15 | 102,277,237 | 102,431,074 | CopyNumber | Variation_2202 (DGV) |
| 15 | 102,305,129 | 102,393,477 | CopyNumber | Variation_8809 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| R54C | R54H | I101M | C141G | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | R | R | I | C | 97.93 | 0.939 |
| 2 | R | R | I | G | 0.77 | 0.939 |
| 3 | R | H | I | C | 0.61 | 0.939 |
| 4 | R | R | M | C | 0.46 | 0.939 |
| 5 | C | R | I | C | 0.23 | 0.939 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR4F6.aApr07-unspliced | main_exon | CDS | chr15 | 101,805,720 | 101,806,655 | + |
| 3UTR | chr15 | 101,806,655 | 101,806,658 | + | ||