OR4K14 Olfactory Receptor
| Gene Symbol | OR4K141 (View this gene in GeneCards) |
| Family | 4 |
| Subfamily | K |
| Pseudogene | No |
| CORP pseudogene probability score | 0.03 (functional) |
| Aliases | OR14-22, OR14-18, HsOR14.1.17, ORL3700 |
| External Ids | HGNC: 15352 GeneBank: AB065880, AF399572, BK004521, BK004816, NM_001004712 ORDB: ORL3700 |
| Build #39 labels | OR4K14 |
| Chromosomal location | 14:20,014,264-20,015,193 (-) |
| Cluster | 14@20b |
| Synteny | CLIC#32 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR4K13 | 67.77% | 301 |
| OR4K15 | 67.21% | 305 |
| OR4K3P | 68% | 300 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR4K13 | 67% | 308 |
| Mouse | Or4k15 | 67% | 305 |
| Rat | Or4k15 | 67% | 305 |
| Cow | OR4K3 | 65% | 305 |
| Orang | OR4K15H | 68% | 305 |
| Horse | OR4K3 | 67% | 305 |
| Chimp | OR4K14P | 97% | 310 |
Expression evidences
| Source | Accession |
|---|---|
| GNF Atlas2 | gnf1h02813_at |
Sequence information
| Nucleotide sequence |
ATGGACCCACAGAACTATTCCTTGGTGTCAGAATTTGTGTTGCATGGACTCTGCACTTCA CGACATCTTCAAAATTTTTTCTTTATATTTTTCTTTGGGGTCTATGTGGCCATTATGCTG GGTAACCTTCTCATTTTGGTCACTGTAATTTCTGATCCCTGCCTGCACTCCTCCCCTATG TACTTCCTGCTGGGGAACCTAGCTTTCCTGGACATGTGGCTGGCCTCATTTGCCACTCCC AAGATGATCAGGGATTTCCTTAGTGATCAAAAACTCATCTCCTTTGGAGGATGTATGGCT CAAATCTTCTTCTTGCACTTTACTGGTGGGGCTGAGATGGTGCTCCTGGTTTCCATGGCC TATGACAGATATGTGGCCATATGCAAACCCTTGCATTACATGACTTTGATGAGTTGGCAG ACTTGCATCAGGCTGGTGCTGGCTTCATGGGTCGTTGGATTTGTGCACTCCATCAGTCAA GTGGCTTTCACTGTAAATTTGCCTTACTGTGGCCCCAATGAGGTAGACAGCTTCTTCTGT GACCTCCCTCTGGTGATCAAACTTGCCTGCATGGACACCTATGTCTTGGGTATAATTATG ATCTCAGACAGTGGGTTGCTTTCCTTGAGCTGTTTTCTGCTCCTCCTGATCTCCTACACC GTGATCCTCCTCGCTATCAGACAGCGTGCTGCCGGTAGCACATCCAAAGCACTCTCCACT TGCTCTGCACATATCATGGTAGTGACGCTGTTCTTTGGCCCTTGCATTTTTGTTTATGTG CGGCCTTTCAGTAGGTTCTCTGTGGACAAGCTGCTGTCTGTGTTTTATACCATTTTTACT CCACTCCTGAACCCCATTATCTACACATTGAGAAATGAGGAGATGAAAGCAGCTATGAAG AAACTGCAAAACCGACGGGTGACTTTTCAA |
| Conceptual translation |
MDPQNYSLVSEFVLHGLCTSRHLQNFFFIFFFGVYVAIMLGNLLILVTVISDPCLHSSPM YFLLGNLAFLDMWLASFATPKMIRDFLSDQKLISFGGCMAQIFFLHFTGGAEMVLLVSMA YDRYVAICKPLHYMTLMSWQTCIRLVLASWVVGFVHSISQVAFTVNLPYCGPNEVDSFFC DLPLVIKLACMDTYVLGIIMISDSGLLSLSCFLLLLISYTVILLAIRQRAAGSTSKALST CSAHIMVVTLFFGPCIFVYVRPFSRFSVDKLLSVFYTIFTPLLNPIIYTLRNEEMKAAMK KLQNRRVTFQ Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 14 | 20,482,919 | 20,482,919 | NS | A/C | L/R | rs17308108 (DbSNP) |
| 14 | 20,482,998 | 20,482,998 | NS | C/T | V/M | rs7157076 (DbSNP) |
| 14 | 20,482,471 | 20,482,471 | SYN | C/T | E/E | rs12590785 (DbSNP) |
| 14 | 20,014,312 | 20,014,312 | SYN | C/T | E/E | 1000GP (CEU, CHBJPT) |
| 14 | 20,014,760 | 20,014,760 | NS | A/C | L/R | 1000GP (CEU, CHBJPT) |
| 14 | 20,014,786 | 20,014,786 | SYN | C/T | L/L | 1000GP (CHBJPT) |
| 14 | 100 | -100 | SYN | C/T | E/E | 1000GP (YRI, YRI) |
| 14 | 100 | -100 | NS | G/A | P/L | 1000GP (YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 14 | 20,371,142 | 20,505,020 | CopyNumber | Variation_2175 (DGV) |
| 14 | 20,203,125 | 20,539,108 | CopyNumber | Variation_3036 (DGV) |
| 14 | 19,662,531 | 20,556,187 | CopyNumber | Variation_3929 (DGV) |
| 14 | 20,362,952 | 20,525,999 | CopyNumber | Variation_4827 (DGV) |
| 14 | 20,203,125 | 20,483,660 | CopyNumber | Variation_8762 (DGV) |
| 14 | 20,203,125 | 20,626,160 | CopyNumber | Variation_8763 (DGV) |
| 14 | 20,203,125 | 20,716,841 | CopyNumber | Variation_8765 (DGV) |
| 14 | 20,239,479 | 20,511,107 | CopyNumber | Variation_9235 (DGV) |
| 14 | 20,203,125 | 20,525,833 | CopyNumber | Variation_34547 (DGV) |
| 14 | 20,203,125 | 20,655,466 | CopyNumber | Variation_34656 (DGV) |
| 14 | 20,203,125 | 20,550,348 | CopyNumber | Variation_34660 (DGV) |
| 14 | 20,465,300 | 20,483,617 | CopyNumber | Variation_76560 (DGV), Variation_87119 (DGV) |
| 14 | 20,473,893 | 20,483,617 | CopyNumber | Variation_87120 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| P281L | V247A | I217V | V152A | L145R | M119V | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|
| 1 | P | V | I | V | L | M | 83.18 | 0.081 |
| 2 | P | V | I | V | R | M | 7.45 | 0.081 |
| 3 | P | V | I | V | L | V | 6.84 | 0.261 |
| 4 | L | V | I | V | L | M | 1.77 | 0.141 |
| 5 | P | A | I | V | L | M | 0.46 | 0.081 |
| 6 | P | V | I | A | L | M | 0.23 | 0.081 |
| 7 | P | V | V | V | L | M | 0.08 | 0.081 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR4K14.aApr07-unspliced | main_exon | 3UTR | chr14 | 20,014,261 | 20,014,264 | - |
| CDS | chr14 | 20,014,264 | 20,015,193 | - | ||