OR4K3P Olfactory Receptor
| Gene Symbol | OR4K3P1 (View this gene in GeneCards) |
| Family | 4 |
| Subfamily | K |
| Pseudogene | Yes |
| CORP pseudogene probability score | |
| Aliases | OR14-14, OR14-10, HsOR14.1.9P |
| External Ids | HGNC: 14731 GeneBank: AB065884, AF399571, BK004358, BK004817, NG_003198 |
| Build #39 labels | OR4K3 |
| Chromosomal location | 14:19,868,200-19,869,143 (-) |
| Cluster | 14@20b |
| Synteny | CLIC#32 |
| Remarks | Segregating Pseudo Gene, a polymorphism of C->del at position 621 (rs5807006) |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR4K14 | 68% | 300 |
| OR4K15 | 66.45% | 304 |
| OR4K2 | 65.36% | 306 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR4K14 | 69% | 310 |
| Mouse | Or4k15 | 65% | 307 |
| Rat | Or4k15 | 66% | 307 |
| Cow | OR4K3 | 87% | 315 |
| Orang | OR4K3BP | 93% | 311 |
| Orang | OR4K3 | 92% | 311 |
| Horse | OR4K3 | 91% | 315 |
| Chimp | OR4K3 | 95% | 315 |
Sequence information
| Nucleotide sequence |
ATGGCCTGGAGCAATCAGTCTGCGGTAACCGAATTCATACTACGGGGTCTGTCCAGTTCT TTAGAACTCCAGATTTTCTACTTCCTGTTTTTCTCCATAGTCTATGCAGCCACTGTGCTG GGGAACCTTCTTATTGTGGTCACCATTGCATCAGAGCCACACCTTCATTCCCCTATGTAC TTTCTGCTGGGCAATCTCTCCTTCATTGACATGTCCCTGGCCTCATTTGCCACCCCCAAA ATGATTGCAGACTTCCTTAGAGAACACAAAGCCATCTCTTTTGAAGGCTGCATGACCCAG ATGTTCTTCCTACATCTCTTAGGGGGTGCTGAGATTGTACTGCTGATCTCCATGTCCTTT GATAGGTACGTGGCTATCTGTAAGCCTCTACATTACCTAACAATCATGAGCCGAAGAATG TGTGTTGGGCTTGTGATACTTTCCTGGATTGTCGGCATCTTCCATGCTCTGAGTCAGTTA GCATTTACAGTGAATCTGCCCTTCTGTGGACCCAATGAAGTAGACAGTTTCTTTTGTGAC CTCCCTTTGGTGATTAAACTTGCTTGTGTTGACACATATATTCTGGGGGTGTTCATGATC TCAACCAGTGGCATGATTGCCTGGTGTGCTTCATCCTCTTGGTGATCTCTTACACTATCA TCCTGGTCACCGTTCGGCAGCGTTCCTCTGGTGGATCCTCCAAAGCCCTCTCCACGTGCA GTGCCCACTTTACTGTTGTGACCCTTTTCTTTGGCCCATGCACTTTCATTTATGTGTGGC CTTTCACAAATTTCCCAATAGACAAAGTACTCTCAGTATTTTATACCATATACACTCCCC TCTTGAATCCAGTGATCTATACCGTTAGGAATAAAGATGTCAAGTATTCCATGAGGAAAC TAAGCAGCCATATCTTTAAATCTAGGAAGACTGATCATACTCCT |
| Conceptual translation |
MAWSNQSAVTEFILRGLSSSLELQIFYFLFFSIVYAATVLGNLLIVVTIASEPHLHSPMY FLLGNLSFIDMSLASFATPKMIADFLREHKAISFEGCMTQMFFLHLLGGAEIVLLISMSF DRYVAICKPLHYLTIMSRRMCVGLVILSWIVGIFHALSQLAFTVNLPFCGPNEVDSFFCD LPLVIKLACVDTYILGVFMISTSGM/CLVCFILLVISYTIILVTVRQRSSGGSSKALST CSAHFTVVTLFFGPCTFIYVWPFTNFPIDKVLSVFYTIYTPLLNPVIYTVRNKDVKYSMR KLSSHIFKSRKTDHTP Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 14 | 20,336,685 | 20,336,684 | Ins(1) | -/G | rs33950294 (DbSNP) | |
| 14 | 20,336,684 | 20,336,683 | Ins(1) | -/G | rs11440549 (DbSNP) | |
| 14 | 20,336,683 | 20,336,682 | Ins(1) | -/G | rs33925594 (DbSNP) | |
| 14 | 20,336,682 | 20,336,681 | rescued_Ins(1) | -/G | rs5807006 (DbSNP) | |
| 14 | 20,336,467 | 20,336,467 | SNP | A/C | rs57581445 (DbSNP) | |
| 14 | 20,336,914 | 20,336,914 | SNP | A/G | rs8013162 (DbSNP) | |
| 14 | 20,336,588 | 20,336,588 | SNP | A/G | rs41313499 (DbSNP) | |
| 14 | 20,336,642 | 20,336,642 | SNP | A/G | rs10132244 (DbSNP) | |
| 14 | 20,336,788 | 20,336,788 | SNP | C/T | rs61188848 (DbSNP) | |
| 14 | 20,337,127 | 20,337,127 | SNP | G/A | rs1780941 (DbSNP) | |
| 14 | 20,336,733 | 20,336,734 | mixed | -/C/T | rs1892239 (DbSNP) | |
| 14 | 19,868,429 | 19,868,429 | SNP | G/A | 1000GP (CEU) | |
| 14 | 19,868,565 | 19,868,565 | SNP | A/G | 1000GP (CEU) | |
| 14 | 19,868,574 | 19,868,574 | SNP | A/G | 1000GP (CEU, CHBJPT) | |
| 14 | 19,868,755 | 19,868,755 | SNP | A/G | 1000GP (CEU, CHBJPT) | |
| 14 | 19,868,968 | 19,868,968 | SNP | A/G | 1000GP (CEU, CHBJPT) | |
| 14 | 100 | -100 | SNP | A/C | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 14 | 20,197,616 | 20,399,048 | CopyNumber | Variation_0316 (DGV) |
| 14 | 20,203,125 | 20,539,108 | CopyNumber | Variation_3036 (DGV) |
| 14 | 19,662,531 | 20,556,187 | CopyNumber | Variation_3929 (DGV) |
| 14 | 20,219,649 | 20,415,445 | CopyNumber | Variation_4826 (DGV) |
| 14 | 19,117,183 | 20,424,605 | CopyNumber | Variation_7028 (DGV) |
| 14 | 20,203,125 | 20,483,660 | CopyNumber | Variation_8762 (DGV) |
| 14 | 20,203,125 | 20,626,160 | CopyNumber | Variation_8763 (DGV) |
| 14 | 20,239,479 | 20,422,583 | CopyNumber | Variation_8764 (DGV) |
| 14 | 20,203,125 | 20,716,841 | CopyNumber | Variation_8765 (DGV) |
| 14 | 20,203,125 | 20,433,044 | CopyNumber | Variation_9234 (DGV) |
| 14 | 20,239,479 | 20,511,107 | CopyNumber | Variation_9235 (DGV) |
| 14 | 20,177,234 | 20,424,604 | CopyNumber | Variation_30648 (DGV) |
| 14 | 19,360,239 | 20,424,604 | CopyNumber | Variation_31953 (DGV) |
| 14 | 20,203,125 | 20,525,833 | CopyNumber | Variation_34547 (DGV) |
| 14 | 20,267,014 | 20,433,060 | CopyNumber | Variation_34563 (DGV) |
| 14 | 20,203,125 | 20,456,434 | CopyNumber | Variation_34575 (DGV) |
| 14 | 20,203,125 | 20,655,466 | CopyNumber | Variation_34656 (DGV) |
| 14 | 20,239,246 | 20,432,988 | CopyNumber | Variation_34659 (DGV) |
| 14 | 20,203,125 | 20,550,348 | CopyNumber | Variation_34660 (DGV) |
| 14 | 20,203,125 | 20,455,307 | CopyNumber | Variation_34664 (DGV) |
| 14 | 20,200,183 | 20,423,372 | CopyNumber | Variation_38951 (DGV) |
| 14 | 20,305,431 | 20,404,091 | CopyNumber | Variation_49301 (DGV) |
| 14 | 20,305,431 | 20,425,051 | CopyNumber | Variation_49302 (DGV), Variation_49303 (DGV) |
| 14 | 20,305,431 | 20,432,664 | CopyNumber | Variation_49304 (DGV) |
| 14 | 19,349,922 | 20,424,856 | CopyNumber | Variation_58655 (DGV) |
| 14 | 20,177,210 | 20,424,753 | CopyNumber | Variation_66584 (DGV) |
| 14 | 19,781,170 | 20,424,776 | CopyNumber | Variation_71833 (DGV) |
| 14 | 20,289,680 | 20,425,312 | CopyNumber | Variation_71860 (DGV) |
| 14 | 20,152,622 | 20,419,574 | CopyNumber | Variation_76554 (DGV), Variation_87112 (DGV) |
| 14 | 20,326,958 | 20,419,574 | CopyNumber | Variation_76555 (DGV) |
| 14 | 20,283,374 | 20,419,574 | CopyNumber | Variation_76556 (DGV) |
| 14 | 20,332,406 | 20,370,542 | CopyNumber | Variation_76558 (DGV) |
| 14 | 20,299,695 | 20,419,574 | CopyNumber | Variation_87113 (DGV) |
| 14 | 20,201,654 | 20,343,302 | CopyNumber | Variation_87118 (DGV) |
| 14 | 20,334,359 | 20,337,402 | Deletion, CopyNumber | #282 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.