OR4K8P Olfactory Receptor
| Gene Symbol | OR4K8P1 (View this gene in GeneCards) |
| Family | 4 |
| Subfamily | K |
| Pseudogene | Yes |
| CORP pseudogene probability score | |
| Aliases | OR18-1, HsOR18.1.2P, ORL3207 |
| External Ids | HGNC: 14787 GeneBank: BK004699, NG_002222 ORDB: ORL3207 |
| Build #39 labels | OR4K8P, OR4K9P |
| Chromosomal location | 18:14,613,210-14,614,163 (+) |
| Cluster | 18@15 |
| Synteny | CLIC#0 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR4K11P | 97.8% | 318 |
| OR4K15 | 93.71% | 318 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR4K15 | 91% | 318 |
| Mouse | Or4k15 | 90% | 318 |
| Rat | Or4k15 | 90% | 318 |
| Cow | OR4K15 | 89% | 311 |
| Orang | OR4K15 | 95% | 318 |
| Orang | OR4K15H | 94% | 318 |
| Horse | OR4K15 | 88% | 318 |
| Chimp | OR4K11P | 97% | 316 |
| Chimp | OR4K11BP | 95% | 301 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | GD260809 |
Sequence information
| Nucleotide sequence |
ATGAATGAGACAAATCATTCTTGGGTGACAGAATTTGTGTTGCTGGGACTGTCTAGTTCA AGGGAGCTCCAACCTTTCTTGTTTCTTATATTTTCACTACTTTATCTAGCAATTCTGTTG GGCAACTTTCTCATCATCCTCACTGTGACCTCAGATTCCCGCCTTCACACCCCCATGTAC TTTCTGCTTGCAAACCTGTCATTTATAGACGTATGTGTTGCCTCTTCTGCTACCCCTAAA ATGATTGCAGACTTTCTGGTTGAGCACAAGACTATTTCTTTTGATGCCCACCTGGCCCAG ATTTTCTTTGTTCATCTCTTCACTGGCAGTGAAATGGTGCTCCTAGTTTCCATGGCCTAT GACCGTTATGTTGCTATATGCAAACCTCCCCACTACATGACAATCATGAGCTGCTGTGTA TGTGTTGTGCTCGTCCTCATTTCCTGGTTTGTGGGCTTCATCCATACCACCAGCCAGTTG GCATTCACGTTAATCTGCCATTTTGTGGTCCTAATAAGGTAGATAGTTTTTTTCTGTGAC CTTCCTCTAGCGACGAAGTTAGCCTGCATAGACACTTATGTTGTCAGCCTACTAATAGTT GCAGATAGTGGCTTTCTTTCTCTGAGTTCCTTTCTCCTCTTGGTTGTCTCCTACACTGTA ATACTTGTTACAGTTAGGAATCGCTCCTCTGTAAGCATGGTGAAGGCCCACTCCACATTG ACTGCTCACATCACTGTGGTCACTTTATTCTTTGGATCGTGTATTTTCATCTATGTGTGG CCCTTCAGCAGTTACTCAGTTGACAAAGTCCTTGCTGTATTCTACACCATCTTCACGTCT ATTTTAAACCCTGTAATCTACATGCTAAGAAACAAAGAAGTGAAGGCAGCTATGTCAAAA CTGAAGAGTCGGTATCAGAAGCTTGGTCAGGTTTCTGTAGTCATAAGAAACGTT |
| Conceptual translation |
MNETNHSWVTEFVLLGLSSSRELQPFLFLIFSLLYLAILLGNFLIILTVTSDSRLHTPMY FLLANLSFIDVCVASSATPKMIADFLVEHKTISFDAHLAQIFFVHLFTGSEMVLLVSMAY DRYVAICKPPHYMTIMSCCVCVVLVLISWFVGFIHTTSQLAFT/NLPFCGPNKVDSFF\br/>CDLPLATKLACIDTYVVSLLIVADSGFLSLSSFLLLVVSYTVILVTVRNRSSVSMVKAHS TLTAHITVVTLFFGSCIFIYVWPFSSYSVDKVLAVFYTIFTSILNPVIYMLRNKEVKAAM SKLKSRYQKLGQVSVVIRNV Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 18 | 100 | -100 | SNP | C/A | 1000GP (YRI, YRI) | |
| 18 | 14,613,507 | 14,613,507 | SNP | C/A | 1000GP (CEU) | |
| 18 | 14,613,726 | 14,613,726 | SNP | A/G | rs8093060 (DbSNP) | |
| 18 | 14,613,759 | 14,613,759 | SNP | C/T | rs2646595 (DbSNP) | |
| 18 | 14,613,763 | 14,613,763 | SNP | C/G | rs2646596 (DbSNP) | |
| 18 | 14,613,815 | 14,613,815 | SNP | A/G | rs12960773 (DbSNP) | |
| 18 | 14,613,890 | 14,613,890 | SNP | A/C | rs2646597 (DbSNP) | |
| 18 | 14,613,917 | 14,613,917 | SNP | C/T | rs2646598 (DbSNP) | |
| 18 | 14,613,918 | 14,613,918 | SNP | A/G | rs2646599 (DbSNP) | |
| 18 | 14,613,965 | 14,613,965 | SNP | C/T | rs2646600 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 182 (Hasin) | |||
| 18 | 13,998,748 | 15,377,893 | CopyNumber | Variation_4053 (DGV) |
| 18 | 14,612,921 | 14,616,051 | CopyNumber | Variation_67309 (DGV) |
| 18 | 14,613,109 | 14,616,162 | Deletion | #244 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.