OR4Q2P Olfactory Receptor
| Gene Symbol | OR4Q2P1 (View this gene in GeneCards) |
| Family | 4 |
| Subfamily | Q |
| Pseudogene | Yes |
| CORP pseudogene probability score | |
| Aliases | OR14-21, HsOR14.1.16P, ORL3713 |
| External Ids | HGNC: 15359 GeneBank: AF399446, AF546532-AF546545, BK004624, NG_004349 ORDB: ORL3713 |
| Build #39 labels | OR4Q2P |
| Chromosomal location | 14:20,002,163-20,003,093 (+) |
| Cluster | 14@20b |
| Synteny | CLIC#32 |
| Remarks | Segregating Pseudo Gene, a polymorphism of 1 bp insertion (T) at position 531 |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR4D5 | 59.52% | 294 |
| OR4M1 | 58.47% | 301 |
| OR4Q3 | 58.36% | 305 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR4Q2 | 91% | 310 |
| Mouse | Or4d5 | 59% | 303 |
| Rat | Or4m1 | 58% | 307 |
| Cow | OR4Q2 | 90% | 310 |
| Orang | OR4D5P | 60% | 303 |
| Horse | OR4Q2 | 91% | 306 |
| Chimp | OR4Q2 | 98% | 310 |
Sequence information
| Nucleotide sequence |
ATGGATAAAAACCAAACAGAAGTGATGAGAGAATTTTTCTTGTCAGGGTTCTCACAGACA CCATCTATTGAAGCAGGGCTATTTGTACTATTTCTTTTCTTCTATATGTCCATTTGGGTT GGCAATGTCCTCATCATGGTCACAGTAGCATCTGATAAATACCTGAATTCATCACCCATG TATTTCCTTCTTGGCAACCTCTCATTTCTGGACCTATGTTATTCAACAGTAACGACCCCT AAGCTTCTGGCTGACTTCTTTAATCATGAAAAACTCATTTCCTATGACCAATGCATTGTG CAACTCTTCTTCCTGCATTTTGTAGGGGCAGCTGAGATGTTCCTGCTCACAGTGATGGCG TACGATCGCTATGTTGCAATCTGTCGCCCGCTGCACTACACCACTGTCATGAGTCGGGGG TTATGCTGTGTGTTGGTTGCTGCCTCCTGGATGGGAGGATTTGTGCACTCCACTGTCCAG ACCATTCTCACTGTCCATCTACCCTTTTGTGGGCCAAATCAGGTGGAAAACTTTTTTTTG TGATGTTCCCCCTGTCATCAAACTTGCTTGTGCTGACACTTTTGTCATTGAATTGCTCAT GGTATCTAACAGTGGGTTGATCTCCACCATCTCCTTTGTGGTGCTGATTTCCTCCTACAC CACTATCCTAGTCAAGATTCGCTCCAAGGAAGGAAGGCGAAAGGCACTCTCCACGTGTGC CTCTCACCTCATGGTGGTAACACTGTTTTTTGGACCCTGTATTTTCATCTACGCTCGTCC TTTCTCTACATTTTCTGTGGACAAGATGGTGTCTGTACTCTACAATGTTATTACCCCAAT GCTAAACCCCCTCATCTACACACTTCGGAACAAAGAGGTAAAGTCAGCCATGCAGAAGCT CTGGGTCAGAAATGGGCTTACTTGGAAAAAG |
| Conceptual translation |
MDKNQTEVMREFFLSGFSQTPSIEAGLFVLFLFFYMSIWVGNVLIMVTVASDKYLNSSPM YFLLGNLSFLDLCYSTVTTPKLLADFFNHEKLISYDQCIVQLFFLHFVGAAEMFLLTVMA YDRYVAICRPLHYTTVMSRGLCCVLVAASWMGGFVHSTVQTILTVHLPFCGPNQVENFF\br/>CDVPPVIKLACADTFVIELLMVSNSGLISTISFVVLISSYTTILVKIRSKEGRRKALSTC ASHLMVVTLFFGPCIFIYARPFSTFSVDKMVSVLYNVITPMLNPLIYTLRNKEVKSAMQK LWVRNGLTWKK Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 14 | 20,470,860 | 20,470,860 | Del(1) | -/T | rs34315947 (DbSNP) | |
| 14 | 20,470,853 | 20,470,853 | Del(1) | -/T | rs67430133 (DbSNP) | |
| 14 | 20,470,825 | 20,470,825 | SNP | A/C | rs74033777 (DbSNP) | |
| 14 | 20,470,399 | 20,470,399 | SNP | A/G | rs7493807 (DbSNP) | |
| 14 | 20,470,737 | 20,470,737 | SNP | A/G | rs12587697 (DbSNP) | |
| 14 | 20,470,903 | 20,470,903 | SNP | C/T | rs12586792 (DbSNP) | |
| 14 | 20,002,226 | 20,002,226 | SNP | T/C | 1000GP (CEU) | |
| 14 | 20,002,240 | 20,002,240 | SNP | G/A | 1000GP (CEU, CHBJPT) | |
| 14 | 20,002,578 | 20,002,578 | SNP | G/A | 1000GP (CEU, CHBJPT) | |
| 14 | 20,002,744 | 20,002,744 | SNP | T/C | 1000GP (CEU, CHBJPT) | |
| 14 | 100 | -100 | SNP | G/A | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 14 | 20,371,142 | 20,505,020 | CopyNumber | Variation_2175 (DGV) |
| 14 | 20,203,125 | 20,539,108 | CopyNumber | Variation_3036 (DGV) |
| 14 | 19,662,531 | 20,556,187 | CopyNumber | Variation_3929 (DGV) |
| 14 | 20,362,952 | 20,525,999 | CopyNumber | Variation_4827 (DGV) |
| 14 | 20,203,125 | 20,483,660 | CopyNumber | Variation_8762 (DGV) |
| 14 | 20,203,125 | 20,626,160 | CopyNumber | Variation_8763 (DGV) |
| 14 | 20,203,125 | 20,716,841 | CopyNumber | Variation_8765 (DGV) |
| 14 | 20,239,479 | 20,511,107 | CopyNumber | Variation_9235 (DGV) |
| 14 | 20,203,125 | 20,525,833 | CopyNumber | Variation_34547 (DGV) |
| 14 | 20,203,125 | 20,655,466 | CopyNumber | Variation_34656 (DGV) |
| 14 | 20,203,125 | 20,550,348 | CopyNumber | Variation_34660 (DGV) |
| 14 | 20,465,300 | 20,483,617 | CopyNumber | Variation_76560 (DGV), Variation_87119 (DGV) |
| 14 | 20,465,300 | 20,477,259 | CopyNumber | Variation_76561 (DGV) |
| CopyNumber | 112 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.