OR4S2 Olfactory Receptor
Gene Symbol | OR4S21 (View this gene in GeneCards) |
Family | 4 |
Subfamily | S |
Pseudogene | No |
CORP pseudogene probability score | 0.21 (functional) |
Aliases | OR11-137, HsOR11.11.19 |
External Ids | HGNC: 15183 GeneBank: AB065516, AF399447, AF546546-AF546559, BK004390, NM_001004059 |
Build #39 labels | OR4S2 |
Chromosomal location | 11:55,650,904-55,651,836 (+) |
Cluster | 11@56 |
Synteny | CLIC#26 |
Remarks |
Most Similar ORs in Humans (Paralogs)
Symbol | Percent | Length |
---|---|---|
OR4B1 | 62.25% | 302 |
OR4P4 | 60.26% | 307 |
OR4X2 | 60.73% | 303 |
Most Similar ORs in other species (Orthologs)
Specie | Symbol | Percent | Length |
---|---|---|---|
Dog | OR4S7 | 68% | 305 |
Mouse | Or4s2 | 90% | 311 |
Mouse | Or4s2b | 88% | 311 |
Rat | Or4s2 | 89% | 311 |
Cow | OR4S2CP | 82% | 303 |
Cow | OR4S2P | 80% | 307 |
Orang | OR4X2P | 61% | 301 |
Horse | OR4S2D | 85% | 311 |
Chimp | OR4X2 | 61% | 303 |
Expression evidences
Source | Accession |
---|---|
mRNA | AB463967 |
GNF Atlas2 | gnf1h05454_at |
Sequence information
Nucleotide sequence |
ATGGAAAAAATAAACAACGTAACTGAATTCATTTTCTGGGGTCTTTCTCAGAGCCCAGAG ATTGAGAAAGTTTGTTTTGTGGTGTTTTCTTTCTTCTACATAATCATTCTTCTGGGAAAT CTCCTCATCATGCTGACAGTTTGCCTGAGCAACCTGTTTAAGTCACCCATGTATTTCTTT CTCAGCTTCTTGTCTTTTGTGGACATTTGTTACTCTTCAGTCACAGCTCCCAAGATGATT GTTGACCTGTTAGCAAAGGACAAAACCATCTCCTATGTGGGGTGCATGTTGCAACTGTTT GGAGTACATTTCTTTGGTTGCACTGAGATCTTCATCCTTACTGTAATGGCCTATGATCGT TATGTGGCTATCTGTAAACCCCTACATTATATGACCATCATGAACCGGGAGACATGCAAT AAAATGTTATTAGGGACGTGGGTAGGTGGGTTCTTACACTCCATTATCCAAGTGGCTCTG GTAGTCCAACTACCCTTTTGTGGACCCAATGAGATAGATCACTACTTTTGTGATGTTCAC CCTGTGTTGAAACTTGCCTGCACAGAAACATACATTGTTGGTGTTGTTGTGACAGCCAAC AGTGGTACCATTGCTCTGGGGAGTTTTGTTATCTTGCTAATCTCCTACAGCATCATCCTA GTTTCCCTGAGAAAGCAGTCAGCAGAAGGCAGGCGCAAAGCCCTCTCCACCTGTGGCTCC CACATTGCCATGGTCGTTATCTTTTTCGGCCCCTGTACTTTTATGTACATGCGCCCTGAT ACGACCTTTTCAGAGGATAAGATGGTGGCTGTATTTTACACCATTATCACTCCCATGTTA AATCCTCTGATTTATACACTGAGAAATGCAGAAGTAAAGAATGCAATGAAGAAACTGTGG GGCAGAAATGTTTTCTTGGAGGCTAAAGGGAAA |
Conceptual translation |
MEKINNVTEFIFWGLSQSPEIEKVCFVVFSFFYIIILLGNLLIMLTVCLSNLFKSPMYFF LSFLSFVDICYSSVTAPKMIVDLLAKDKTISYVGCMLQLFGVHFFGCTEIFILTVMAYDR YVAICKPLHYMTIMNRETCNKMLLGTWVGGFLHSIIQVALVVQLPFCGPNEIDHYFCDVH PVLKLACTETYIVGVVVTANSGTIALGSFVILLISYSIILVSLRKQSAEGRRKALSTCGS HIAMVVIFFGPCTFMYMRPDTTFSEDKMVAVFYTIITPMLNPLIYTLRNAEVKNAMKKLW GRNVFLEAKGK Protein domains and features |
Variations - SNPs
Chr | Start | End | Type | Variation | AA Change | SNP IDs |
---|---|---|---|---|---|---|
11 | 55,418,593 | 55,418,593 | NS | A/T | T/S | rs17146960 (DbSNP) |
11 | 55,418,693 | 55,418,693 | NS | C/T | S/F | rs11230541 (DbSNP) |
11 | 55,418,677 | 55,418,677 | NS | C/T | L/F | rs6591569 (DbSNP) |
11 | 55,418,963 | 55,418,963 | NS | G/T | G/V | rs7949664 (DbSNP) |
11 | 55,651,487 | 55,651,487 | NS | T/G | V/G | 1000GP (CEU) |
11 | 55,651,217 | 55,651,217 | NS | T/C | F/S | 1000GP (CEU, CHBJPT) |
11 | 100 | -100 | NS | T/A | S/T | 1000GP (YRI, YRI, YRI, YRI) |
11 | 100 | -100 | SYN | C/T | Y/Y | 1000GP (YRI) |
Variations - CNVs
Chr | Start | End | Type | Sources |
---|---|---|---|---|
11 | 55,153,930 | 55,816,828 | CopyNumber | Variation_0308 (DGV) |
11 | 55,359,025 | 55,470,359 | CopyNumber | Variation_0419 (DGV), Variation_34977 (DGV) |
11 | 55,339,702 | 55,638,112 | CopyNumber | Variation_2926 (DGV) |
11 | 55,222,420 | 55,621,884 | CopyNumber | Variation_3852 (DGV) |
11 | 55,382,681 | 55,548,038 | CopyNumber | Variation_4743 (DGV) |
11 | 55,367,167 | 55,452,993 | CopyNumber | Variation_6923 (DGV) |
11 | 54,835,623 | 55,879,426 | CopyNumber | Variation_8690 (DGV) |
11 | 55,377,006 | 55,620,699 | CopyNumber | Variation_9188 (DGV) |
11 | 55,371,021 | 55,422,586 | CopyNumber | Variation_9662 (DGV), Variation_48831 (DGV) |
11 | 55,360,213 | 55,447,427 | CopyNumber | Variation_9663 (DGV), Variation_48827 (DGV) |
11 | 55,371,021 | 55,447,427 | CopyNumber | Variation_10359 (DGV), Variation_48834 (DGV), Variation_48835 (DGV) |
11 | 55,364,237 | 55,431,910 | Inversion | Variation_29474 (DGV) |
11 | 55,360,213 | 55,447,426 | CopyNumber | Variation_29606 (DGV) |
11 | 55,371,020 | 55,460,788 | CopyNumber | Variation_29910 (DGV) |
11 | 55,367,884 | 55,459,183 | CopyNumber | Variation_31823 (DGV) |
11 | 55,362,651 | 55,460,561 | CopyNumber | Variation_34978 (DGV) |
11 | 55,358,496 | 55,434,466 | CopyNumber | Variation_37484 (DGV) |
11 | 55,374,032 | 55,453,009 | CopyNumber | Variation_38079 (DGV) |
11 | 55,368,154 | 55,450,788 | CopyNumber | Variation_38972 (DGV) |
11 | 55,365,425 | 55,431,552 | CopyNumber | Variation_41253 (DGV) |
11 | 55,335,878 | 55,453,486 | CopyNumber | Variation_48051 (DGV) |
11 | 55,381,588 | 55,474,194 | CopyNumber | Variation_48053 (DGV) |
11 | 55,360,213 | 55,442,368 | CopyNumber | Variation_48826 (DGV) |
11 | 55,360,213 | 55,470,003 | CopyNumber | Variation_48828 (DGV) |
11 | 55,371,021 | 55,437,126 | CopyNumber | Variation_48832 (DGV) |
11 | 55,371,021 | 55,442,368 | CopyNumber | Variation_48833 (DGV) |
11 | 55,371,021 | 55,460,095 | CopyNumber | Variation_48836 (DGV) |
11 | 55,383,157 | 55,447,427 | CopyNumber | Variation_48837 (DGV), Variation_53573 (DGV) |
11 | 55,396,041 | 55,442,368 | CopyNumber | Variation_48839 (DGV) |
11 | 55,339,829 | 55,447,427 | CopyNumber | Variation_53140 (DGV) |
11 | 55,408,664 | 55,447,427 | CopyNumber | Variation_53178 (DGV) |
11 | 55,360,213 | 55,490,377 | CopyNumber | Variation_53507 (DGV) |
11 | 55,360,213 | 55,460,788 | CopyNumber | Variation_53994 (DGV) |
11 | 55,360,213 | 55,470,994 | CopyNumber | Variation_54018 (DGV) |
11 | 55,364,677 | 55,453,061 | CopyNumber | Variation_65955 (DGV) |
11 | 55,366,131 | 55,452,023 | CopyNumber | Variation_75644 (DGV) |
11 | 55,365,707 | 55,452,023 | CopyNumber | Variation_85779 (DGV) |
Deletion | 254 (Hasin) | |||
11 | 55,418,280 | 55,421,312 | Deletion | #10 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
S72T | V81I | F105S | V195G | L213Q | R232C | M296V | % Freq | CORP | |
---|---|---|---|---|---|---|---|---|---|
1 | S | V | F | V | L | R | M | 72.12 | 0.409 |
2 | S | V | S | V | L | R | M | 18.43 | 0.409 |
3 | S | V | F | G | L | R | M | 3.38 | 0.409 |
4 | T | V | S | V | L | C | M | 2.53 | 0.409 |
5 | S | I | F | V | L | R | M | 1.38 | 0.409 |
6 | S | V | S | V | L | C | M | 0.84 | 0.409 |
7 | S | V | F | V | L | R | V | 0.38 | 0.409 |
8 | S | I | F | V | Q | R | M | 0.38 | 0.409 |
9 | S | V | F | V | Q | R | M | 0.23 | 0.409 |
10 | S | V | F | V | L | C | M | 0.23 | 0.409 |
11 | S | V | F | G | L | C | M | 0.08 | 0.409 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
Accession | Type | Chr | Start | End | Strand | |
---|---|---|---|---|---|---|
OR4S2.aApr07-unspliced | main_exon | CDS | chr11 | 55,650,904 | 55,651,836 | + |
3UTR | chr11 | 55,651,836 | 55,651,839 | + |