OR51B5 Olfactory Receptor
| Gene Symbol | OR51B51 (View this gene in GeneCards) |
| Family | 51 |
| Subfamily | B |
| Pseudogene | No |
| CORP pseudogene probability score | 0.09 (functional) |
| Aliases | OR11-37, HsOR11.3.59 |
| External Ids | HGNC: 19599 GeneBank: BC022184, BK004430, NM_001005567 |
| Build #39 labels | OR51B5 |
| Chromosomal location | 11:5,342,589-5,343,524 (-) |
| Cluster | 11@5 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR51B2 | 67.43% | 304 |
| OR51B4 | 65.02% | 303 |
| OR51B6 | 70.92% | 306 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR51B18 | 73% | 304 |
| Mouse | Or51b6 | 75% | 301 |
| Rat | Or51b6 | 74% | 301 |
| Cow | OR51B19P | 62% | 291 |
| Orang | OR51B5P | 95% | 312 |
| Horse | OR51B6 | 72% | 306 |
| Chimp | OR51B5BP | 95% | 312 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136708 |
Sequence information
| Nucleotide sequence |
ATGTCGTCCAGCGGCAGCTCCCATCCCTTCCTATTGACTGGTTTTCCAGGCTTGGAGGAA GCTCATCACTGGATTTCCGTATTTTTCTTGTTCATGTATATATCCATCCTTTTTGGCAAT GGCACCCTCCTTCTTCTCATTAAGGAAGATCACAATCTTCATGAGCCCATGTACTTCTTT CTGGCCATGCTGGCTGCCACAGACCTGGGGCTGGCCCTGACCACAATGCCCACGGTGCTG GGAGTCCTCTGGCTGGATCACAGGGAGATTGGAAGTGCGGCCTGCTTTTCCCAGGCCTAC TTTATACACTCACTTTCCTTTCTCGAGTCTGGCATTCTGCTTGCCATGGCCTATGACCGT TTTATTGCCATCTGCAACCCTCTTAGATATACCTCTGTACTTACTAATACTCGAGTAGTG AAGATTGGGCTGGGAGTTCTGATGAGGGGATTTGTATCCGTTGTTCCCCCAATCAGGCCC CTCTATTTTTTTCTGTATTGTCACTCCCATGTTCTTTCACATGCATTCTGCCTTCACCAG GATGTCATTAAACTCGCCTGTGCTGATACCACCTTCAACCGACTGTACCCAGCTGTGCTT GTAGTCTTTATATTTGTGCTGGATTATCTGATTATCTTCATCTCCTATGTGTTGATACTC AAGACTGTCCTGAGCATTGCCTCCAGAGAGGAGAGGGCCAAGGCTCTCATTACCTGTGTC TCCCATATCTGCTGTGTCCTGGTTTTTTATGTCACAGTGATTGGATTGTCTCTGATTCAT CGTTTTGGAAAGCAGGTTCCACATATTGTTCACCTCATTATGAGCTATGCCTATTTTCTG TTCCCTCCACTAATGAATCCTATAACATATAGTGTCAAGACCAAGCAGATTCAGAATGCC ATTCTTCACCTTTTTACTACCCATAGAATTGGAACC |
| Conceptual translation |
MSSSGSSHPFLLTGFPGLEEAHHWISVFFLFMYISILFGNGTLLLLIKEDHNLHEPMYFF LAMLAATDLGLALTTMPTVLGVLWLDHREIGSAACFSQAYFIHSLSFLESGILLAMAYDR FIAICNPLRYTSVLTNTRVVKIGLGVLMRGFVSVVPPIRPLYFFLYCHSHVLSHAFCLHQ DVIKLACADTTFNRLYPAVLVVFIFVLDYLIIFISYVLILKTVLSIASREERAKALITCV SHICCVLVFYVTVIGLSLIHRFGKQVPHIVHLIMSYAYFLFPPLMNPITYSVKTKQIQNA ILHLFTTHRIGT Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 5,363,840 | 5,363,840 | Del(1) | -/A | rs34017644 (DbSNP) | |
| 11 | 5,364,450 | 5,364,450 | NS | A/G | I/T | rs11036912 (DbSNP) |
| 11 | 5,364,097 | 5,364,097 | NS | A/G | F/L | rs7120319 (DbSNP) |
| 11 | 5,364,276 | 5,364,276 | NS | A/G | L/P | rs4910551 (DbSNP) |
| 11 | 5,364,471 | 5,364,471 | NS | C/G | C/S | rs61738484 (DbSNP) |
| 11 | 5,364,493 | 5,364,493 | NS | C/T | G/R | rs57900141 (DbSNP) |
| 11 | 5,364,742 | 5,364,742 | NS | C/T | G/S | rs11036913 (DbSNP) |
| 11 | 5,364,295 | 5,364,295 | NS | C/T | V/I | rs12273630 (DbSNP) |
| 11 | 5,364,522 | 5,364,522 | NS | G/T | T/K | rs57273781 (DbSNP) |
| 11 | 5,364,174 | 5,364,174 | NS | T/C | Q/R | rs61743611 (DbSNP) |
| 11 | 5,364,431 | 5,364,431 | SYN | A/G | L/L | rs58233587 (DbSNP) |
| 11 | 5,364,296 | 5,364,296 | SYN | C/G | S/S | rs62000378 (DbSNP) |
| 11 | 5,364,476 | 5,364,476 | SYN | T/C | A/A | rs61738485 (DbSNP) |
| 11 | 5,343,246 | 5,343,246 | SYN | C/T | A/A | 1000GP (CEU) |
| 11 | 5,343,263 | 5,343,263 | NS | T/C | R/G | 1000GP (CEU) |
| 11 | 5,343,065 | 5,343,065 | NS | C/T | V/I | 1000GP (CEU) |
| 11 | 5,343,292 | 5,343,292 | NS | G/T | T/K | 1000GP (CEU) |
| 11 | 5,343,201 | 5,343,201 | SYN | G/A | L/L | 1000GP (CEU) |
| 11 | 5,343,046 | 5,343,046 | NS | G/A | P/L | 1000GP (CEU, CHBJPT) |
| 11 | 5,343,512 | 5,343,512 | NS | C/T | G/S | 1000GP (CEU, CHBJPT) |
| 11 | 5,343,220 | 5,343,220 | NS | A/G | I/T | 1000GP (CEU, CHBJPT) |
| 11 | 5,342,783 | 5,342,783 | NS | C/T | V/I | 1000GP (CHBJPT) |
| 11 | 100 | -100 | NS | G/A | L/F | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | G/C | S/S | 1000GP (YRI, YRI, YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| V248I | L220F | H179Y | P160L | V154I | I102T | C95S | R88G | T78K | G5S | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | V | L | H | L | V | T | C | R | T | G | 27.50 | 0.059 |
| 2 | V | L | H | P | V | I | C | R | T | S | 27.04 | 0.059 |
| 3 | V | L | H | P | V | I | C | R | T | G | 23.58 | 0.059 |
| 4 | V | L | H | P | I | I | C | G | K | G | 10.06 | 0.059 |
| 5 | V | F | H | P | V | I | C | R | T | G | 7.45 | 0.059 |
| 6 | V | L | H | L | V | T | C | G | T | G | 1.23 | 0.059 |
| 7 | V | L | Y | L | V | T | C | R | T | G | 1.08 | 0.059 |
| 8 | V | L | H | L | V | T | S | R | T | G | 0.69 | 0.836 |
| 9 | I | L | H | P | V | I | C | R | T | S | 0.54 | 0.059 |
| 10 | V | L | H | P | V | I | C | G | K | G | 0.31 | 0.059 |
| 11 | V | L | H | P | I | I | C | G | T | G | 0.08 | 0.059 |
| 12 | V | L | H | P | V | T | C | R | T | G | 0.08 | 0.059 |
| 13 | V | L | H | P | V | I | S | R | T | S | 0.08 | 0.836 |
| 14 | V | L | H | L | I | I | C | R | T | S | 0.08 | 0.059 |
| 15 | V | L | H | L | V | T | S | R | K | G | 0.08 | 0.836 |
| 16 | V | L | H | L | I | I | C | R | T | G | 0.08 | 0.059 |
| 17 | V | L | H | P | V | T | S | R | T | G | 0.08 | 0.836 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR51B5.aApr07 | main_exon | 3UTR | chr11 | 5,342,586 | 5,342,589 | - |
| CDS | chr11 | 5,342,589 | 5,343,524 | - | ||
| 5UTR | chr11 | 5,343,524 | 5,343,629 | - | ||
| exon_5UTR | chr11 | 5,345,773 | 5,345,899 | - | ||
| exon_5UTR | chr11 | 5,346,262 | 5,346,353 | - | ||
| exon_5UTR | chr11 | 5,346,876 | 5,346,910 | - | ||