OR51B6 Olfactory Receptor
| Gene Symbol | OR51B61 (View this gene in GeneCards) |
| Family | 51 |
| Subfamily | B |
| Pseudogene | No |
| CORP pseudogene probability score | 1 (pseudogene) |
| Aliases | HsOR11.3.60 |
| External Ids | HGNC: 19600 GeneBank: NM_001004750 |
| Build #39 labels | OR51B6 |
| Chromosomal location | 11:5,351,508-5,352,443 (+) |
| Cluster | 11@5 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR51B2 | 69.97% | 303 |
| OR51B4 | 67.97% | 306 |
| OR51B5 | 70.92% | 306 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR51B9 | 76% | 312 |
| Mouse | Or51b6 | 86% | 312 |
| Rat | Or51b6 | 86% | 312 |
| Cow | OR51B19P | 71% | 300 |
| Orang | OR51B5P | 71% | 306 |
| Horse | OR51B26P | 73% | 299 |
| Chimp | OR51B5 | 72% | 306 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB463972 |
Sequence information
| Nucleotide sequence |
ATGGGGCTCAATAAGTCTGCTTCCACCTTCCAGCTTACTGGCTTCCCAGGCATGGAGAAG GCACATCACTGGATATTCATCCCATTATTGGCAGCCTACATCTCCATACTTCTTGGCAAT GGCACTCTTCTCTTTCTCATCAGGAATGATCATAACCTCCATGAGCCCATGTACTATTTC TTAGCTATGTTGGCAGCTACAGACCTCGGAGTGACATTGACCACAATGCCCACAGTGCTA GGTGTTCTGTGGTTAGATCACAGGGAGATTGGCCATGGAGCCTGCTTCTCTCAGGCCTAT TTTATCCATACTCTTTCTGTCATGGAGTCAGGTGTCTTGCTTGCCATGGCTTATGACTGT TTCATTACCATCCGCAGCCCCTTAAGATATACCTCTATCCTGACCAACACCCAGGTAATG AAGATTGGTGTGCGGGTATTGACAAGGGCTGGTCTGTCCATTATGCCAATAGTTGTTCGC CTACACTGGTTTCCCTACTGTCGATCCCATGTACTCTCCCATGCTTTCTGTCTACACCAA GATGTCATCAAGCTAGCCTGTGCTGACATCACCTTCAACCGTCTCTATCCAGTTGTAGTT TTATTTGCAATGGTCTTGTTGGACTTTCTCATCATCTTTTTCTCCTACATTTTGATTCTC AAGACTGTCATGGGCATTGGTTCTGGAGGAGAAAGGGCCAAGGCCCTCAACACATGTGTC TCTCATATCTGCTGCATCCTGGTCTTCTATGTCACTGTAGTTTGTCTGACATTTATTCAT AGGTTTGGAAAGCATGTTCCTCATGTCGTTCACATCACAATGAGCTACATCCACTTCCTT TTCCCACCTTTTATGAACCCATTTATCTATAGCATTAAAACTAAGCAGATTCAGAGTGGC ATACTTCGTTTATTCTCTCTGCCTCACTCTAGAGCA |
| Conceptual translation |
MGLNKSASTFQLTGFPGMEKAHHWIFIPLLAAYISILLGNGTLLFLIRNDHNLHEPMYYF LAMLAATDLGVTLTTMPTVLGVLWLDHREIGHGACFSQAYFIHTLSVMESGVLLAMAYDC FITIRSPLRYTSILTNTQVMKIGVRVLTRAGLSIMPIVVRLHWFPYCRSHVLSHAFCLHQ DVIKLACADITFNRLYPVVVLFAMVLLDFLIIFFSYILILKTVMGIGSGGERAKALNTCV SHICCILVFYVTVVCLTFIHRFGKHVPHVVHITMSYIHFLFPPFMNPFIYSIKTKQIQSG ILRLFSLPHSRA Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 5,372,751 | 5,372,751 | NS | A/C | K/T | rs4910755 (DbSNP) |
| 11 | 5,373,562 | 5,373,562 | NS | A/C | R/S | rs5024042 (DbSNP) |
| 11 | 5,373,111 | 5,373,111 | NS | A/G | H/R | rs7479477 (DbSNP) |
| 11 | 5,373,104 | 5,373,104 | NS | A/G | T/A | rs5006889 (DbSNP) |
| 11 | 5,373,114 | 5,373,114 | NS | A/G | N/S | rs5006888 (DbSNP) |
| 11 | 5,372,856 | 5,372,856 | NS | A/G | N/S | rs4910756 (DbSNP) |
| 11 | 5,373,497 | 5,373,497 | NS | C/G | L/V | rs7106330 (DbSNP) |
| 11 | 5,373,170 | 5,373,170 | NS | C/G | R/G | rs5006886 (DbSNP) |
| 11 | 5,373,251 | 5,373,251 | NS | C/T | L/F | rs5006884 (DbSNP) |
| 11 | 5,373,006 | 5,373,006 | NS | C/T | T/I | rs7483122 (DbSNP) |
| 11 | 5,373,129 | 5,373,129 | NS | C/T | T/I | rs5006887 (DbSNP) |
| 11 | 5,373,311 | 5,373,311 | NS | C/T | L/F | rs5006883 (DbSNP) |
| 11 | 5,373,242 | 5,373,242 | NS | G/T | A/S | rs5006885 (DbSNP) |
| 11 | 5,373,334 | 5,373,334 | SYN | A/G | V/V | rs5006882 (DbSNP) |
| 11 | 5,372,863 | 5,372,863 | SYN | A/T | T/T | rs10837882 (DbSNP) |
| 11 | 5,373,646 | 5,373,646 | SYN | C/T | R/R | rs5024041 (DbSNP) |
| 11 | 5,352,012 | 5,352,012 | NS | T/G | S/A | 1000GP (CEU, CHBJPT) |
| 11 | 5,351,874 | 5,351,874 | NS | A/G | T/A | 1000GP (CEU, CHBJPT) |
| 11 | 5,352,021 | 5,352,021 | NS | C/T | L/F | 1000GP (CEU, CHBJPT) |
| 11 | 5,351,940 | 5,351,940 | NS | C/G | R/G | 1000GP (CEU, CHBJPT) |
| 11 | 5,351,881 | 5,351,881 | NS | G/A | R/H | 1000GP (CEU, CHBJPT) |
| 11 | 5,351,899 | 5,351,899 | NS | C/T | T/I | 1000GP (CEU, CHBJPT) |
| 11 | 5,352,081 | 5,352,081 | NS | T/C | F/L | 1000GP (CEU, CHBJPT) |
| 11 | 5,352,422 | 5,352,422 | NS | C/G | F/L | 1000GP (CEU) |
| 11 | 5,352,267 | 5,352,267 | NS | G/C | V/L | 1000GP (CEU, CHBJPT) |
| 11 | 5,351,884 | 5,351,884 | NS | G/A | S/N | 1000GP (CEU, CHBJPT) |
| 11 | 5,352,079 | 5,352,079 | NS | C/A | T/N | 1000GP (CEU, CHBJPT) |
| 11 | 5,351,865 | 5,351,865 | NS | T/C | C/R | 1000GP (CEU, CHBJPT) |
| 11 | 5,351,651 | 5,351,651 | SYN | G/A | R/R | 1000GP (CEU, CHBJPT) |
| 11 | 5,352,416 | 5,352,416 | SYN | T/C | R/R | 1000GP (CEU, CHBJPT) |
| 11 | 5,352,332 | 5,352,332 | NS | C/A | S/R | 1000GP (CEU, CHBJPT) |
| 11 | 5,351,626 | 5,351,626 | NS | A/G | N/S | 1000GP (CEU) |
| 11 | 5,351,894 | 5,351,894 | NS | A/C | R/S | 1000GP (CEU) |
| 11 | 5,351,776 | 5,351,776 | NS | T/C | I/T | 1000GP (CEU, CHBJPT) |
| 11 | 5,351,521 | 5,351,521 | NS | A/C | K/T | 1000GP (CEU, CHBJPT) |
| 11 | 5,351,633 | 5,351,633 | SYN | T/A | T/T | 1000GP (CEU, CHBJPT) |
| 11 | 5,352,104 | 5,352,104 | SYN | A/G | V/V | 1000GP (CEU, CHBJPT) |
| 11 | 100 | -100 | NS | A/C | K/T | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | T/A | T/T | 1000GP (YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 5,372,010 | 5,384,809 | CopyNumber | Variation_71259 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| K5T | N40S | I90T | C120R | T131I | R145G | S169A | L172F | V254L | S275R | L280F | R303C | F305L | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | K | N | I | C | T | R | S | L | V | S | L | R | F | 66.13 | 1.000 |
| 2 | K | N | I | C | T | R | S | L | L | S | L | R | F | 10.14 | 1.000 |
| 3 | T | S | T | C | I | G | A | F | V | R | L | R | F | 9.52 | 1.000 |
| 4 | T | N | T | R | I | G | A | F | V | R | L | R | F | 6.22 | 1.000 |
| 5 | T | S | T | R | I | G | A | F | V | R | L | R | F | 4.38 | 1.000 |
| 6 | T | N | T | R | I | G | A | F | V | R | F | R | F | 1.08 | 1.000 |
| 7 | K | N | I | C | T | R | A | L | V | S | L | R | F | 0.77 | 1.000 |
| 8 | K | N | I | C | T | R | S | L | L | S | L | R | L | 0.46 | 1.000 |
| 9 | T | S | I | C | I | G | A | F | V | R | L | R | F | 0.23 | 1.000 |
| 10 | T | S | T | C | I | G | A | F | V | R | L | C | F | 0.23 | 1.000 |
| 11 | T | S | T | R | T | G | A | F | V | R | L | R | F | 0.15 | 1.000 |
| 12 | K | N | T | C | I | G | A | F | V | S | L | R | F | 0.15 | 1.000 |
| 13 | T | S | T | C | T | G | A | F | V | S | L | R | F | 0.15 | 1.000 |
| 14 | T | S | T | C | T | G | A | F | V | R | L | R | F | 0.08 | 1.000 |
| 15 | T | S | T | C | I | G | A | F | V | S | L | R | F | 0.08 | 1.000 |
| 16 | T | S | T | R | T | R | S | L | V | S | L | R | F | 0.08 | 1.000 |
| 17 | K | N | I | C | T | G | S | L | V | S | L | R | F | 0.08 | 1.000 |
| 18 | T | S | T | C | I | G | A | L | V | R | L | R | F | 0.08 | 1.000 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR51B6.aApr07-unspliced | main_exon | CDS | chr11 | 5,351,508 | 5,352,443 | + |
| 3UTR | chr11 | 5,352,443 | 5,352,446 | + | ||