OR51E2 Olfactory Receptor
| Gene Symbol | OR51E21 (View this gene in GeneCards) |
| Family | 51 |
| Subfamily | E |
| Pseudogene | No |
| CORP pseudogene probability score | 0.04 (functional) |
| Aliases | OR11-16, HsOR11.3.16, ORL3397 |
| External Ids | HGNC: 15195 GeneBank: AF311306, AF369708, BK004368 ORDB: ORL3397 |
| Build #39 labels | OR51E2 |
| Chromosomal location | 11:4,681,752-4,682,711 (-) |
| Cluster | 11@5 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR51D1 | 58.63% | 307 |
| OR51G2 | 56.39% | 305 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR51D1 | 61% | 300 |
| Mouse | Or51e2 | 93% | 319 |
| Rat | Or51d1 | 60% | 305 |
| Cow | OR51E1 | 59% | 306 |
| Orang | OR51E1 | 59% | 306 |
| Horse | OR51E1 | 59% | 308 |
| Chimp | OR51E1 | 59% | 306 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | EL735395 |
| mRNA | CU676708 |
| GNF Atlas2 | 221424_s_at |
Sequence information
| Nucleotide sequence |
ATGAGTTCCTGCAACTTCACACATGCCACCTTTGTGCTTATTGGTATCCCAGGATTAGAG AAAGCCCATTTCTGGGTTGGCTTCCCCCTCCTTTCCATGTATGTAGTGGCAATGTTTGGA AACTGCATCGTGGTCTTCATCGTAAGGACGGAACGCAGCCTGCACGCTCCGATGTACCTC TTTCTCTGCATGCTTGCAGCCATTGACCTGGCCTTATCCACATCCACCATGCCTAAGATC CTTGCCCTTTTCTGGTTTGATTCCCGAGAGATTAGCTTTGAGGCCTGTCTTACCCAGATG TTCTTTATTCATGCCCTCTCAGCCATTGAATCCACCATCCTGCTGGCCATGGCCTTTGAC CGTTATGTGGCCATCTGCCACCCACTGCGCCATGCTGCAGTGCTCAACAATACAGTAACA GCCCAGATTGGCATCGTGGCTGTGGTCCGCGGATCCCTCTTTTTTTTCCCACTGCCTCTG CTGATCAAGCGGCTGGCCTTCTGCCACTCCAATGTCCTCTCGCACTCCTATTGTGTCCAC CAGGATGTAATGAAGTTGGCCTATGCAGACACTTTGCCCAATGTGGTATATGGTCTTACT GCCATTCTGCTGGTCATGGGCGTGGACGTAATGTTCATCTCCTTGTCCTATTTTCTGATA ATACGAACGGTTCTGCAACTGCCTTCCAAGTCAGAGCGGGCCAAGGCCTTTGGAACCTGT GTGTCACACATTGGTGTGGTACTCGCCTTCTATGTGCCACTTATTGGCCTCTCAGTGGTA CACCGCTTTGGAAACAGCCTTCATCCCATTGTGCGTGTTGTCATGGGTGACATCTACCTG CTGCTGCCTCCTGTCATCAATCCCATCATCTATGGTGCCAAAACCAAACAGATCAGAACA CGGGTGCTGGCTATGTTCAAGATCAGCTGTGACAAGGACTTGCAGGCTGTGGGAGGCAAG |
| Conceptual translation |
MSSCNFTHATFVLIGIPGLEKAHFWVGFPLLSMYVVAMFGNCIVVFIVRTERSLHAPMYL FLCMLAAIDLALSTSTMPKILALFWFDSREISFEACLTQMFFIHALSAIESTILLAMAFD RYVAICHPLRHAAVLNNTVTAQIGIVAVVRGSLFFFPLPLLIKRLAFCHSNVLSHSYCVH QDVMKLAYADTLPNVVYGLTAILLVMGVDVMFISLSYFLIIRTVLQLPSKSERAKAFGTC VSHIGVVLAFYVPLIGLSVVHRFGNSLHPIVRVVMGDIYLLLPPVINPIIYGAKTKQIRT RVLAMFKISCDKDLQAVGGK Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 4,703,654 | 4,703,654 | SYN | A/G | C/C | rs12575331 (DbSNP) |
| 11 | 4,703,165 | 4,703,165 | SYN | C/A | V/V | rs1123991 (DbSNP) |
| 11 | 4,703,420 | 4,703,420 | SYN | C/T | S/S | rs7939559 (DbSNP) |
| 11 | 4,703,321 | 4,703,321 | SYN | G/A | G/G | rs1123990 (DbSNP) |
| 11 | 4,703,762 | 4,703,762 | SYN | G/T | L/L | rs12576387 (DbSNP) |
| 11 | 4,682,532 | 4,682,532 | SYN | G/T | L/L | 1000GP (CEU, CHBJPT) |
| 11 | 4,682,190 | 4,682,190 | SYN | C/T | S/S | 1000GP (CEU, CHBJPT) |
| 11 | 4,681,935 | 4,681,935 | SYN | C/A | V/V | 1000GP (CEU, CHBJPT) |
| 11 | 4,682,091 | 4,682,091 | SYN | G/A | G/G | 1000GP (CHBJPT) |
| 11 | 4,682,424 | 4,682,424 | SYN | A/G | C/C | 1000GP (CHBJPT) |
| 11 | 100 | -100 | SYN | C/A | V/V | 1000GP (YRI, YRI, YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 200 (Hasin) | |||
| 11 | 4,700,982 | 4,704,041 | CopyNumber | #53 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| T112S | A56S | % Freq | CORP | |
|---|---|---|---|---|
| 1 | T | A | 98.95 | 0.040 |
| 2 | S | A | 0.73 | 0.040 |
| 3 | T | S | 0.31 | 0.040 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR51E2.aApr07 | main_exon | 3UTR | chr11 | 4,680,171 | 4,681,752 | - |
| CDS | chr11 | 4,681,752 | 4,682,711 | - | ||
| 5UTR | chr11 | 4,682,711 | 4,682,761 | - | ||
| exon_5UTR | chr11 | 4,697,653 | 4,697,845 | - | ||
| OR51E2.bApr07 | main_exon | CDS_partial | chr11 | 4,682,461 | 4,682,711 | - |
| 5UTR | chr11 | 4,682,711 | 4,682,761 | - | ||
| exon_5UTR | chr11 | 4,697,653 | 4,697,845 | - | ||