OR51F1 Olfactory Receptor
| Gene Symbol | OR51F11 (View this gene in GeneCards) |
| Family | 51 |
| Subfamily | F |
| Pseudogene | No |
| CORP pseudogene probability score | 0.76 (pseudogene) |
| Aliases | OR11-21, HsOR11.3.22 |
| External Ids | HGNC: 15196 GeneBank: NM_001004752 |
| Build #39 labels | OR51F1P |
| Chromosomal location | 11:4,768,982-4,769,917 (-) |
| Cluster | 11@5 |
| Synteny | CLIC#23 |
| Remarks | Segregating Pseudo Gene, a polymorphism of C->del at position 274 |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR51F2 | 63.14% | 312 |
| OR51F3P | 62.16% | 296 |
| OR51F5P | 62.88% | 299 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR51F2 | 66% | 312 |
| Mouse | Or51f1 | 82% | 311 |
| Rat | Or51f1 | 79% | 311 |
| Cow | OR51F1B | 82% | 312 |
| Orang | OR51F1P | 92% | 312 |
| Horse | OR51F1C | 81% | 312 |
| Chimp | OR51F1P | 97% | 268 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC172882 |
Sequence information
| Nucleotide sequence |
ATGGAAATCCTAAGCAACTCAACATCTAAATTTCCAACCTTCTTGTTGACCGGCATTCCT GGCCTAGAGTCTGCCCATGTCTGGATCTCCATTCCTTTCTGTTGTTTTTATGCCATTGCC CTCTCTGGGAACAGCGTGATCCTGTTTGTCATCATTACCCAGCAGAGTCTCCATGAACCC ATGTATTATTTCCTCTTCAGGCTATCAGCCACTGATCTGGGCTTGACTGTTTCTTCATTG TCAACAACATTAGGTATCCTCTGGTTTGAGGCACGTGAAATCAGTCTATATAGCTGCATT GTCCAGATGTTTTTTCTTCATGGATTCACTTTTATGGAATCTGGAGTGCTGGTGGCTACA GCCTTTGACCGTTATGTGGCCATCTGTGACCCTCTGAGGTACACTACCATTCTCACTAAT TCCAGAATCATTCAAATGGGTCTTCTGATGATTACACGTGCTATAGTACTAATATTGCCA CTACTTTTGCTCCTTAAGCCTCTCTATTTCTGTAGAATGAATGCCCTTTCTCACTCCTAT TGTTACCATCCAGATGTGATTCAATTAGCATGTTCAGACATTCGGGCAAATAGCATCTGT GGATTAATTGATCTCATCCTGACCACTGGAATAGATACACCATGCATTGTCCTGTCATAT ATCTTAATTATTCACTCTGTCCTCAGAATTGCCTCCCCTGAAGAATGGCACAAGGTCTTC AGCACCTGTGTCTCCCATGTGGGAGCAGTTGCTTTCTTCTACATCCACATGCTGAGCCTG TCCTTGGTGTATCGCTATGGTCGGTCAGCCCCCAGAGTAGTCCATTCAGTGATGGCTAAT GTATACCTGCTTTTACCCCCTGTGCTCAACCCCATCATCGACAGTGTAAAAACAAAACAA ATCCGCAAGGCTATGCTCAGTCTGCTGCTTACAAAA |
| Conceptual translation |
MEILSNSTSKFPTFLLTGIPGLESAHVWISIPFCCFYAIALSGNSVILFVIITQQSLHEP MYYFLFRLSATDLGLTVSSLSTTLGILWFEAREISLYSCIVQMFFLHGFTFMESGVLVAT AFDRYVAICDPLRYTTILTNSRIIQMGLLMITRAIVLILPLLLLLKPLYFCRMNALSHSY CYHPDVIQLACSDIRANSICGLIDLILTTGIDTPCIVLSYILIIHSVLRIASPEEWHKVF STCVSHVGAVAFFYIHMLSLSLVYRYGRSAPRVVHSVMANVYLLLPPVLNPIIDSVKTKQ IRKAMLSLLLTK Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 4,790,874 | 4,790,874 | Del(1) | -/G | rs34672924 (DbSNP) | |
| 11 | 4,790,948 | 4,790,948 | NS | A/C | M/R | rs11033800 (DbSNP) |
| 11 | 4,790,951 | 4,790,951 | NS | A/G | F/S | rs11033801 (DbSNP) |
| 11 | 4,790,396 | 4,790,396 | NS | A/G | V/A | rs17324609 (DbSNP) |
| 11 | 4,790,268 | 4,790,268 | NS | C/A | D/Y | rs1030726 (DbSNP) |
| 11 | 4,790,474 | 4,790,474 | NS | C/T | R/H | rs11033793 (DbSNP) |
| 11 | 4,790,564 | 4,790,564 | NS | C/T | R/Q | rs16938368 (DbSNP) |
| 11 | 4,790,682 | 4,790,682 | NS | C/T | V/I | rs74052100 (DbSNP) |
| 11 | 4,791,111 | 4,791,111 | NS | C/T | A/T | rs17324812 (DbSNP) |
| 11 | 4,790,471 | 4,790,471 | NS | G/A | S/F | rs1030723 (DbSNP) |
| 11 | 4,790,857 | 4,790,857 | SYN | A/G | Y/Y | rs11033797 (DbSNP) |
| 11 | 4,790,575 | 4,790,575 | SYN | A/G | C/C | rs12788102 (DbSNP) |
| 11 | 4,791,046 | 4,791,046 | SYN | A/G | C/C | rs16938394 (DbSNP) |
| 11 | 4,790,758 | 4,790,758 | SYN | A/G | D/D | rs11033796 (DbSNP) |
| 11 | 4,790,671 | 4,790,671 | SYN | C/T | L/L | rs11033795 (DbSNP) |
| 11 | 4,790,482 | 4,790,482 | SYN | C/T | L/L | rs12792898 (DbSNP) |
| 11 | 4,790,410 | 4,790,410 | SYN | G/A | H/H | rs1030724 (DbSNP) |
| 11 | 4,790,308 | 4,790,308 | SYN | G/A | N/N | rs1030725 (DbSNP) |
| 11 | 4,769,881 | 4,769,881 | NS | T/C | T/A | 1000GP (CEU, CHBJPT) |
| 11 | 4,769,345 | 4,769,345 | SYN | A/G | C/C | 1000GP (CEU) |
| 11 | 4,769,375 | 4,769,375 | SYN | A/G | C/C | 1000GP (CEU) |
| 11 | 4,769,528 | 4,769,528 | SYN | G/A | D/D | 1000GP (CEU) |
| 11 | 4,769,651 | 4,769,651 | SYN | A/G | F/F | 1000GP (CEU) |
| 11 | 4,769,241 | 4,769,241 | NS | G/A | S/F | 1000GP (CEU) |
| 11 | 4,769,180 | 4,769,180 | SYN | A/G | H/H | 1000GP (CEU) |
| 11 | 4,769,252 | 4,769,252 | SYN | T/C | L/L | 1000GP (CEU) |
| 11 | 4,769,441 | 4,769,441 | SYN | C/T | L/L | 1000GP (CEU) |
| 11 | 4,769,718 | 4,769,718 | NS | C/A | R/M | 1000GP (CEU) |
| 11 | 4,769,078 | 4,769,078 | SYN | A/G | N/N | 1000GP (CEU) |
| 11 | 4,769,244 | 4,769,244 | NS | T/C | H/R | 1000GP (CEU) |
| 11 | 4,769,721 | 4,769,721 | NS | A/G | F/S | 1000GP (CEU) |
| 11 | 4,769,166 | 4,769,166 | NS | G/A | A/V | 1000GP (CEU) |
| 11 | 4,769,038 | 4,769,038 | NS | C/A | D/Y | 1000GP (CEU) |
| 11 | 4,769,627 | 4,769,627 | SYN | A/G | Y/Y | 1000GP (CEU) |
| 11 | 4,769,660 | 4,769,660 | SYN | G/A | I/I | 1000GP (CHBJPT) |
| 11 | 4,769,691 | 4,769,691 | NS | G/A | T/I | 1000GP (CHBJPT) |
| 11 | 100 | -100 | NS | C/A | D/Y | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | A/G | N/N | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 4,790,280 | 4,790,889 | InDel | Variation_71252 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| K312E | D294Y | A251V | S226F | H225R | H225Y | R195Q | V156I | T76I | R67M | F66S | P32R | T13A | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | K | D | A | S | H | H | R | V | T | R | F | P | T | 60.29 | 0.802 |
| 2 | K | D | A | S | H | H | R | V | T | R | F | P | A | 13.67 | 0.802 |
| 3 | K | Y | A | F | R | H | R | V | T | M | S | P | T | 13.59 | 0.802 |
| 4 | K | Y | V | S | H | H | R | V | T | M | S | P | T | 5.99 | 0.802 |
| 5 | K | Y | A | F | R | Y | R | V | T | M | S | P | T | 2.00 | 0.802 |
| 6 | K | D | A | S | H | H | R | I | T | R | F | P | T | 1.08 | 0.802 |
| 7 | K | D | A | S | H | H | R | V | I | R | F | P | T | 0.92 | 0.802 |
| 8 | K | Y | A | S | H | H | R | V | T | M | S | P | T | 0.77 | 0.802 |
| 9 | K | Y | V | S | H | H | R | V | T | R | F | P | T | 0.46 | 0.802 |
| 10 | K | Y | A | S | H | H | R | V | T | R | F | P | T | 0.31 | 0.802 |
| 11 | E | Y | A | F | R | H | R | V | T | M | S | P | T | 0.31 | 0.802 |
| 12 | K | D | A | F | R | H | R | V | T | M | S | P | T | 0.15 | 0.802 |
| 13 | K | Y | A | F | R | H | Q | V | T | M | S | P | T | 0.15 | 0.802 |
| 14 | K | D | A | S | H | H | R | V | T | R | F | R | T | 0.15 | 0.802 |
| 15 | K | D | A | S | H | H | R | V | T | M | S | P | T | 0.08 | 0.802 |
| 16 | K | D | A | S | H | H | Q | V | T | R | F | P | T | 0.08 | 0.802 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR51F1.aApr07-unspliced | main_exon | 3UTR | chr11 | 4,768,979 | 4,768,982 | - |
| CDS | chr11 | 4,768,982 | 4,769,917 | - | ||