OR51G1 Olfactory Receptor
| Gene Symbol | OR51G11 (View this gene in GeneCards) |
| Family | 51 |
| Subfamily | G |
| Pseudogene | No |
| CORP pseudogene probability score | |
| Aliases | OR11-29, HsOR11.3.35, ORL3445 |
| External Ids | HGNC: 14738 GeneBank: AB065793, BK004286, NM_001005237 ORDB: ORL3445 |
| Build #39 labels | OR51G1, OR51G3P |
| Chromosomal location | 11:4,923,377-4,924,339 (-) |
| Cluster | 11@5 |
| Synteny | CLIC#23 |
| Remarks | Segregating Pseudo Gene, a nonsynonymous SNP in a highly conserved amino-acid (G->A at position 371, R130H) |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR51G2 | 63.82% | 304 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR51G2 | 66% | 297 |
| Mouse | Or51g1 | 89% | 313 |
| Rat | Or51g1 | 88% | 313 |
| Cow | OR51G1BP | 82% | 321 |
| Cow | OR51G1CP | 80% | 321 |
| Orang | OR51G1P | 86% | 313 |
| Horse | OR51G1P | 84% | 322 |
| Chimp | OR51G2P | 61% | 298 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136861 |
| GNF Atlas2 | gnf1h11128_at |
Sequence information
| Nucleotide sequence |
ATGACAATTCTTCTTAATAGCAGCCTCCAAAGAGCCACTTTCTTCCTGACGGGCTTCCAA GGTCTAGAAGGTCTCCATGGCTGGATCTCTATTCCCTTCTGCTTCATCTACCTGACAGTT ATCTTGGGGAACCTCACCATTCTCCACGTCATTTGTACTGATGCCACTCTCCATGGACCC ATGTACTATTTCTTGGGCATGCTAGCTGTCACAGACTTAGGCCTTTGCCTTTCCACACTG CCCACTGTGCTGGGCATTTTCTGGTTTGATACCAGAGAGATTGGCATCCCTGCCTGTTTC ACTCAGCTCTTCTTCATCCACACCTTGTCTTCAATGGAGTCATCAGTTCTGTTATCCATG TCCATTGACCGCTACGTGGCCGTCTGCAACCCACTGCATGACTCCACCGTCCTGACACCT GCATGTATTGTCAAGATGGGGCTAAGCTCAGTGCTTAGAAGTGCTCTCCTCATCCTCCCC TTGCCATTCCTCCTGAAGCGCTTCCAATACTGCCACTCCCATGTGCTGGCTCATGCTTAT TGTCTTCACCTGGAGATCATGAAGCTGGCCTGCTCTAGCATCATTGTCAATCACATCTAT GGGCTCTTTGTTGTGGCCTGCACCGTGGGTGTGGACTCCCTGCTCATCTTTCTCTCATAC GCCCTCATCCTTCGCACCGTGCTCAGCATTGCCTCCCACCAGGAGCGACTCCGAGCCCTC AACACCTGTGTCTCTCATATCTGTGCTGTACTGCTCTTCTACATCCCCATGATTGGCTTG TCTCTTGTGCATCGCTTTGGTGAACATCTGCCCCGCGTTGTACACCTCTTCATGTCCTAT GTGTATCTGCTGGTACCACCCCTTATGAACCCCATCATCTACAGCATCAAGACCAAGCAA ATTCGCCAGCGCATCATTAAGAAGTTTCAGTTTATAAAGTCACTTAGGTGTTTTTGGAAG GAT |
| Conceptual translation |
MTILLNSSLQRATFFLTGFQGLEGLHGWISIPFCFIYLTVILGNLTILHVICTDATLHGP MYYFLGMLAVTDLGLCLSTLPTVLGIFWFDTREIGIPACFTQLFFIHTLSSMESSVLLSM SIDRYVAVCNPLHDSTVLTPACIVKMGLSSVLRSALLILPLPFLLKRFQYCHSHVLAHAY CLHLEIMKLACSSIIVNHIYGLFVVACTVGVDSLLIFLSYALILRTVLSIASHQERLRAL NTCVSHICAVLLFYIPMIGLSLVHRFGEHLPRVVHLFMSYVYLLVPPLMNPIIYSIKTKQ IRQRIIKKFQFIKSLRCFWKD Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | C/G | Q/H | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | C/T | L/L | 1000GP (YRI, YRI) |
| 11 | 4,923,562 | 4,923,562 | SYN | A/G | L/L | 1000GP (CHBJPT) |
| 11 | 4,923,662 | 4,923,662 | SYN | G/C | T/T | 1000GP (CEU) |
| 11 | 4,923,756 | 4,923,756 | NS | A/G | I/T | 1000GP (CEU) |
| 11 | 4,923,966 | 4,923,966 | NS | T/G | Y/S | 1000GP (CEU, CHBJPT) |
| 11 | 4,923,969 | 4,923,969 | NS | C/T | R/H | 1000GP (CEU) |
| 11 | 4,923,999 | 4,923,999 | NS | G/A | S/L | 1000GP (CEU, CHBJPT) |
| 11 | 4,924,003 | 4,924,003 | NS | C/T | E/K | 1000GP (CEU) |
| 11 | 4,924,006 | 4,924,006 | NS | T/C | M/V | 1000GP (CEU) |
| 11 | 4,944,661 | 4,944,661 | NS | C/G | Q/H | rs57920748 (DbSNP) |
| 11 | 4,944,790 | 4,944,790 | SYN | C/T | L/L | rs59534473 (DbSNP) |
| 11 | 4,944,792 | 4,944,792 | SYN | A/G | L/L | rs57025946 (DbSNP) |
| 11 | 4,944,892 | 4,944,892 | SYN | C/G | T/T | rs34583466 (DbSNP) |
| 11 | 4,944,986 | 4,944,986 | NS | A/G | I/T | rs12796015 (DbSNP) |
| 11 | 4,945,196 | 4,945,196 | NS | T/G | Y/S | rs1378739 (DbSNP) |
| 11 | 4,945,199 | 4,945,199 | NS | C/T | R/H | rs34742470 (DbSNP) |
| 11 | 4,945,229 | 4,945,229 | NS | A/G | L/S | rs10836954 (DbSNP) |
| 11 | 4,945,233 | 4,945,233 | NS | C/T | E/K | rs35264256 (DbSNP) |
| 11 | 4,945,236 | 4,945,236 | NS | C/T | V/M | rs35666095 (DbSNP) |
| 11 | 4,945,445 | 4,945,444 | Ins(1) | -/C | rs35069588 (DbSNP) | |
| 11 | 4,945,539 | 4,945,539 | NS | T/C | R/G | rs61732340 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 166 (Hasin) | |||
| 11 | 4,907,893 | 5,135,331 | CopyNumber | Variation_3835 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| C317Y | Q303H | R302C | V281A | I195T | V137I | Q102* | R11G | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | C | Q | R | V | I | V | Q | R | 88.86 | 1.000 |
| 2 | C | Q | R | V | T | V | Q | R | 6.07 | 1.000 |
| 3 | C | H | R | V | I | V | Q | R | 2.15 | 1.000 |
| 4 | C | Q | R | A | I | V | Q | G | 1.08 | 1.000 |
| 5 | C | Q | R | A | I | V | Q | R | 0.84 | 1.000 |
| 6 | C | Q | R | A | I | I | Q | G | 0.38 | 1.000 |
| 7 | C | Q | C | V | I | V | Q | R | 0.23 | 1.000 |
| 8 | C | Q | R | V | T | V | * | R | 0.23 | 1.200 |
| 9 | Y | Q | R | V | I | V | Q | R | 0.15 | 1.000 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR51G1.aApr07-unspliced | main_exon | 3UTR | chr11 | 4,923,374 | 4,923,377 | - |
| CDS | chr11 | 4,923,377 | 4,924,339 | - | ||