OR51Q1 Olfactory Receptor
| Gene Symbol | OR51Q11 (View this gene in GeneCards) |
| Family | 51 |
| Subfamily | Q |
| Pseudogene | No |
| CORP pseudogene probability score | |
| Aliases | HsOR11.3.63, ORL3380 |
| External Ids | HGNC: 14851 GeneBank: NM_001004757 ORDB: ORL3380 |
| Build #39 labels | OR51Q1 |
| Chromosomal location | 11:5,422,201-5,423,151 (+) |
| Cluster | 11@5 |
| Synteny | CLIC#23 |
| Remarks | Segregating Pseudo Gene, a nonsynonymous SNP rs2647574 (AA change=R/* ) |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR51G2 | 58.48% | 289 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR51Q1F | 84% | 315 |
| Mouse | Or51q1 | 84% | 315 |
| Mouse | Or51q1c | 83% | 315 |
| Rat | Or51q1e | 85% | 315 |
| Rat | Or51q1 | 83% | 315 |
| Rat | Or51q1d | 83% | 315 |
| Cow | OR51Q6P | 78% | 314 |
| Orang | OR51Q1P | 94% | 317 |
| Horse | OR51Q9 | 76% | 299 |
| Chimp | OR51L1 | 50% | 313 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | AV732431 |
| mRNA | BC136999 |
Sequence information
| Nucleotide sequence |
ATGTCCCAGGTGACTAACACCACACAAGAAGGCATCTACTTCATCCTCACGGACATCCCT GGATTTGAGGCCTCCCACATCTGGATCTCCATCCCCGTCTGCTGTCTCTACACCATCTCC ATCATGGGCAATACCACCATCCTCACTGTCATTCGCACAGAGCCATCTGTCCACCAGCGC ATGTATCTGTTTCTCTCCATGCTGGCCCTGACGGACCTGGGTCTCACCCTCACCACCCTA CCCACAGTCATGCAGCTTCTCTGGTTCAACGTTCGTAGAATCAGCTCTGAGGCCTGTTTT GCTCAGTTTTTCTTCCTTCATGGATTCTCCTTTATGGAGTCTTCTGTCCTCCTGGCTATG TCCGTTGACTGCTATGTGGCCATCTGCTGTCCCCTCCATTATGCCTCCATCCTCACCAAT GAAGTCATTGGTAGAACTGGGTTAGCCATCATTTGCTGCTGTGTTCTGGCGGTTCTTCCC TCCCTTTTCTTACTCAAGCGACTGCCTTTCTGCCACTCCCACCTTCTCTCTCGCTCCTAT TGCCTCCACCAGGATATGATCCGCCTGGTCTGTGCTGACATCAGGCTCAACAGCTGGTAT GGATTTGCTCTTGCCTTGCTCATTATTATCGTGGATCCTCTGCTCATTGTGATCTCCTAT ACACTTATTCTGAAAAATATCTTGGGCACAGCCACCTGGGCTGAGCGACTCCGTGCCCTC AATAACTGCCTGTCCCACATTCTAGCTGTCCTGGTCCTCTACATTCCCATGGTTGGTGTA TCTATGACTCATCGCTTTGCCAAGCATGCCTCTCCACTGGTCCATGTTATCATGGCCAAT ATCTACCTGCTGGCACCCCCGGTGATGAACCCCATCATTTACAGTGTAAAGAACAAGCAG ATCCAATGGGGAATGTTAAATTTCCTTTCCCTCAAAAATATGCATTCAAGA |
| Conceptual translation |
MSQVTNTTQEGIYFILTDIPGFEASHIWISIPVCCLYTISIMGNTTILTVIRTEPSVHQR MYLFLSMLALTDLGLTLTTLPTVMQLLWFNVRRISSEACFAQFFFLHGFSFMESSVLLAM SVDCYVAICCPLHYASILTNEVIGRTGLAIICCCVLAVLPSLFLLKRLPFCHSHLLSRSY CLHQDMIRLVCADIRLNSWYGFALALLIIIVDPLLIVISYTLILKNILGTATWAERLRAL NNCLSHILAVLVLYIPMVGVSMTHRFAKHASPLVHVIMANIYLLAPPVMNPIIYSVKNKQ IQWGMLNFLSLKNMHSR Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | nonsense SNP | C/T | R/* | 1000GP (YRI) |
| 11 | 100 | -100 | NS | C/T | T/I | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | G/C | V/V | 1000GP (YRI, YRI, YRI, YRI) |
| 11 | 5,422,212 | 5,422,212 | SYN | G/C | V/V | 1000GP (CEU, CHBJPT) |
| 11 | 5,422,401 | 5,422,401 | NS | G/T | M/I | 1000GP (CEU) |
| 11 | 5,422,470 | 5,422,470 | SYN | C/T | N/N | 1000GP (CEU, CHBJPT) |
| 11 | 5,422,500 | 5,422,500 | SYN | T/C | F/F | 1000GP (CEU) |
| 11 | 5,422,509 | 5,422,509 | SYN | T/C | F/F | 1000GP (CEU, CHBJPT) |
| 11 | 5,422,637 | 5,422,637 | NS | C/T | T/I | 1000GP (CEU, CHBJPT) |
| 11 | 5,422,657 | 5,422,657 | NS | T/C | C/R | 1000GP (CEU, CHBJPT) |
| 11 | 5,422,663 | 5,422,663 | NS | G/A | V/I | 1000GP (CEU, CHBJPT) |
| 11 | 5,422,733 | 5,422,733 | NS | G/A | R/H | 1000GP (CEU, CHBJPT) |
| 11 | 5,422,739 | 5,422,739 | NS | A/C | Y/S | 1000GP (CEU, CHBJPT) |
| 11 | 5,422,810 | 5,422,810 | NS | C/T | L/F | 1000GP (CHBJPT) |
| 11 | 5,422,831 | 5,422,831 | NS | G/A | V/M | 1000GP (CEU, CHBJPT) |
| 11 | 5,422,906 | 5,422,906 | nonsense SNP | C/T | R/* | 1000GP (CEU, CHBJPT) |
| 11 | 5,422,920 | 5,422,920 | SYN | C/T | L/L | 1000GP (CEU) |
| 11 | 5,423,123 | 5,423,123 | NS | T/C | F/S | 1000GP (CEU, CHBJPT) |
| 11 | 5,443,442 | 5,443,442 | SYN | C/G | V/V | rs2736590 (DbSNP) |
| 11 | 5,443,643 | 5,443,643 | SYN | G/A | T/T | rs2736589 (DbSNP) |
| 11 | 5,443,700 | 5,443,700 | SYN | T/C | N/N | rs2736588 (DbSNP) |
| 11 | 5,443,739 | 5,443,739 | SYN | T/C | F/F | rs2736587 (DbSNP) |
| 11 | 5,443,867 | 5,443,867 | NS | C/T | T/I | rs10838092 (DbSNP) |
| 11 | 5,443,887 | 5,443,887 | NS | C/T | R/C | rs10838093 (DbSNP) |
| 11 | 5,443,893 | 5,443,893 | NS | A/G | I/V | rs10838094 (DbSNP) |
| 11 | 5,443,963 | 5,443,963 | NS | A/G | H/R | rs10838095 (DbSNP) |
| 11 | 5,443,969 | 5,443,969 | NS | A/C | Y/S | rs58283839 (DbSNP) |
| 11 | 5,444,061 | 5,444,061 | NS | G/A | V/M | rs2736586 (DbSNP) |
| 11 | 5,444,136 | 5,444,136 | nonsense SNP | T/C | */R | rs2647574 (DbSNP) |
| 11 | 5,444,338 | 5,444,337 | Ins(1) | -/G | rs35273709 (DbSNP) | |
| 11 | 5,444,353 | 5,444,353 | NS | T/C | F/S | rs2647573 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 96 (Hasin) | |||
| 11 | 5,416,622 | 5,492,033 | CopyNumber | Variation_2901 (DGV) |
| 11 | 5,431,984 | 5,493,309 | CopyNumber | Variation_9174 (DGV) |
| 11 | 5,443,331 | 5,446,381 | Deletion | #199 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| M67I | T146I | C153R | V155I | R178H | R188H | L204F | V211M | S219F | R236* | R265H | F308S | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | M | T | C | V | R | R | L | V | S | R | R | F | 53.30 | 0.992 |
| 2 | M | I | R | I | H | R | L | M | S | * | R | S | 41.55 | 1.200 |
| 3 | M | T | C | V | R | R | F | V | S | R | R | F | 1.69 | 0.992 |
| 4 | M | T | C | V | R | R | L | V | F | R | R | F | 1.00 | 0.997 |
| 5 | M | I | R | I | H | R | L | M | S | * | R | F | 0.38 | 1.200 |
| 6 | M | T | C | V | H | R | L | M | S | * | R | S | 0.31 | 1.200 |
| 7 | M | I | R | I | H | R | L | V | S | * | R | S | 0.31 | 1.200 |
| 8 | M | I | C | V | H | R | L | M | S | * | R | S | 0.23 | 1.200 |
| 9 | M | T | C | V | R | R | L | V | S | R | H | F | 0.15 | 0.992 |
| 10 | M | T | C | V | R | H | L | V | S | R | R | F | 0.15 | 0.992 |
| 11 | M | T | C | V | R | R | L | V | S | * | R | F | 0.15 | 1.200 |
| 12 | M | T | C | V | R | R | F | M | S | R | R | F | 0.15 | 0.992 |
| 13 | I | T | C | V | R | R | L | V | S | R | R | F | 0.08 | 0.992 |
| 14 | M | T | C | I | H | R | L | M | S | * | R | S | 0.08 | 1.200 |
| 15 | M | I | R | I | R | R | L | M | S | * | R | S | 0.08 | 1.200 |
| 16 | M | T | C | V | R | R | F | V | S | R | R | S | 0.08 | 0.992 |
| 17 | M | T | C | V | R | R | L | M | S | R | R | F | 0.08 | 0.992 |
| 18 | M | I | R | I | H | H | L | M | S | * | R | S | 0.08 | 1.200 |
| 19 | M | I | R | I | H | R | L | V | S | * | R | F | 0.08 | 1.200 |
| 20 | M | I | C | V | R | R | L | V | S | R | R | F | 0.08 | 0.992 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR51Q1.aApr07-unspliced | main_exon | CDS | chr11 | 5,422,201 | 5,423,151 | + |
| 3UTR | chr11 | 5,423,151 | 5,423,154 | + | ||