OR51S1 Olfactory Receptor
| Gene Symbol | OR51S11 (View this gene in GeneCards) |
| Family | 51 |
| Subfamily | S |
| Pseudogene | No |
| CORP pseudogene probability score | 1 (pseudogene) |
| Aliases | OR11-24, HsOR11.3.27, ORL3325 |
| External Ids | HGNC: 15204 GeneBank: AB065796, BK004280, NM_001004758 ORDB: ORL3325 |
| Build #39 labels | OR51S1 |
| Chromosomal location | 11:4,848,240-4,849,163 (-) |
| Cluster | 11@5 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR51G1 | 45.97% | 298 |
| OR51G2 | 46.62% | 296 |
| OR51L1 | 42.72% | 302 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR51G2 | 49% | 293 |
| Mouse | Or51s1 | 82% | 307 |
| Rat | Or51s1 | 81% | 307 |
| Cow | OR51S1B | 82% | 307 |
| Orang | OR51G2 | 47% | 293 |
| Horse | OR51G2 | 48% | 296 |
| Chimp | OR51G2P | 46% | 293 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136934 |
| GNF Atlas2 | gnf1h10944_at |
Sequence information
| Nucleotide sequence |
ATGGCCCCCACCTTCTTGCTGGTGGGCATGCCAGGCCTATCAGGTGCACCCTCCTGGTGG ACATTGCCCCTCATTGCTGTCTACCTTCTCTCTGCACTGGGAAATGGCACCATCCTCTGG ATCATTGCCCTGCAGCCCGCCCTGCACCGCCCAATGCACTTCTTCCTCTTCTTGCTTAGT GTGTCTGATATTGGATTGGTCACTGCCCTGATGCCCACACTGCTGGGCATCGCCCTTGCT GGTGCTCACACTGTCCCTGCCTCAGCCTGCCTTCTACAGATGGTTTTTATCCATGTCTTT TCTGTCATGGAGTCCTCTGTCTTGCTCGCCATGTCCATTGATCGGGCACTGGCCATCTGC CGACCTCTCCACTACCCAGCGCTCCTCACCAATGGTGTAATTAGCAAAATCAGCCTGGCC ATTTCTTTTCGATGCCTGGGTCTCCATCTGCCCCTGCCATTCCTGCTGGCCTACATGCCC TACTGCCTCCCACAGGTCCTAACCCATTCTTATTGCTTGCATCCAGATGTGGCTCGTTTG GCCTGCCCAGAAGCTTGGGGTGCAGCCTACAGCCTATTTGTGGTTCTTTCAGCCATGGGT TTGGACCCCCTGCTTATTTTCTTCTCCTATGGCCTGATTGGCAAGGTGTTGCAAGGTGTG GAGTCCAGAGAGGATCGCTGGAAGGCTGGTCAAACCTGTGCTGCCCACCTCTCTGCAGTG CTCCTCTTCTATATCCCTATGATCCTCCTGGCACTGATTAACCATCCTGAGCTGCCAATC ACTCAGCATACCCATACTCTTCTATCCTATGTCCATTTCCTTCTTCCTCCATTGATAAAC CCTATTCTCTATAGTGTCAAGATGAAGGAGATTAGAAAGAGAATACTCAACAGGTTGCAG CCCAGGAAGGTGGGTGGTGCTCAG |
| Conceptual translation |
MAPTFLLVGMPGLSGAPSWWTLPLIAVYLLSALGNGTILWIIALQPALHRPMHFFLFLLS VSDIGLVTALMPTLLGIALAGAHTVPASACLLQMVFIHVFSVMESSVLLAMSIDRALAIC RPLHYPALLTNGVISKISLAISFRCLGLHLPLPFLLAYMPYCLPQVLTHSYCLHPDVARL ACPEAWGAAYSLFVVLSAMGLDPLLIFFSYGLIGKVLQGVESREDRWKAGQTCAAHLSAV LLFYIPMILLALINHPELPITQHTHTLLSYVHFLLPPLINPILYSVKMKEIRKRILNRLQ PRKVGGAQ Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | G/A | L/F | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | G/A | V/V | 1000GP (YRI) |
| 11 | 4,848,419 | 4,848,419 | NS | G/A | L/F | 1000GP (CEU, CHBJPT) |
| 11 | 4,848,676 | 4,848,676 | NS | A/C | L/R | 1000GP (CEU, CHBJPT) |
| 11 | 4,848,909 | 4,848,909 | SYN | G/A | V/V | 1000GP (CEU, CHBJPT) |
| 11 | 4,849,031 | 4,849,031 | NS | G/C | Q/E | 1000GP (CEU, CHBJPT) |
| 11 | 4,849,039 | 4,849,039 | NS | A/T | I/N | 1000GP (CEU, CHBJPT) |
| 11 | 4,849,054 | 4,849,054 | NS | G/C | T/S | 1000GP (CEU) |
| 11 | 4,849,068 | 4,849,068 | SYN | T/G | A/A | 1000GP (CEU, CHBJPT) |
| 11 | 4,869,649 | 4,869,649 | NS | A/G | F/L | rs12361955 (DbSNP) |
| 11 | 4,869,792 | 4,869,792 | NS | A/G | L/S | rs57238061 (DbSNP) |
| 11 | 4,869,906 | 4,869,906 | NS | A/C | L/R | rs7117260 (DbSNP) |
| 11 | 4,869,992 | 4,869,992 | SYN | A/G | I/I | rs7117389 (DbSNP) |
| 11 | 4,870,139 | 4,870,139 | SYN | A/G | V/V | rs11602455 (DbSNP) |
| 11 | 4,870,261 | 4,870,261 | NS | C/G | E/Q | rs11602499 (DbSNP) |
| 11 | 4,870,269 | 4,870,269 | NS | A/T | I/N | rs12417164 (DbSNP) |
| 11 | 4,870,284 | 4,870,284 | NS | C/G | S/T | rs35918613 (DbSNP) |
| 11 | 4,870,298 | 4,870,298 | SYN | G/T | A/A | rs11601065 (DbSNP) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 89 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| L311V | L264F | R241G | L216S | Y186C | L178R | L123F | Q60E | I57N | T52S | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | L | L | R | L | Y | L | L | Q | I | T | 53.30 | 0.837 |
| 2 | L | F | R | L | Y | R | L | E | I | T | 16.51 | 0.837 |
| 3 | L | L | R | L | Y | R | L | Q | N | T | 10.91 | 0.837 |
| 4 | L | F | R | L | Y | R | L | E | I | S | 6.37 | 0.837 |
| 5 | L | L | R | L | Y | R | L | Q | I | T | 3.92 | 0.837 |
| 6 | L | F | R | S | Y | R | L | Q | I | T | 3.69 | 0.837 |
| 7 | L | F | R | S | Y | R | L | E | I | T | 2.46 | 0.837 |
| 8 | L | L | R | L | Y | R | F | Q | I | T | 0.84 | 0.337 |
| 9 | L | L | R | L | Y | R | L | E | I | T | 0.54 | 0.837 |
| 10 | L | L | R | L | Y | L | L | Q | N | T | 0.38 | 0.837 |
| 11 | L | L | R | L | C | L | L | Q | I | T | 0.23 | 0.837 |
| 12 | L | L | R | L | Y | R | L | E | I | S | 0.23 | 0.837 |
| 13 | V | L | R | L | Y | R | L | E | I | T | 0.23 | 0.837 |
| 14 | L | L | G | L | Y | R | L | Q | I | T | 0.15 | 0.837 |
| 15 | L | L | R | S | Y | L | L | Q | I | T | 0.08 | 0.837 |
| 16 | L | F | R | L | Y | R | L | Q | I | T | 0.08 | 0.837 |
| 17 | L | L | G | L | Y | L | L | Q | I | T | 0.08 | 0.837 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR51S1.aApr07-unspliced | main_exon | 3UTR | chr11 | 4,848,237 | 4,848,240 | - |
| CDS | chr11 | 4,848,240 | 4,849,163 | - | ||
| 5UTR | chr11 | 4,849,163 | 4,849,208 | - | ||