OR52A1 Olfactory Receptor
| Gene Symbol | OR52A11 (View this gene in GeneCards) |
| Family | 52 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 0.08 (functional) |
| Aliases | OR11-319, HPFH1OR, HsOR11.3.51, ORL3331 |
| External Ids | HGNC: 8318 GeneBank: BK004431, NM_012375 ORDB: ORL3331 |
| Build #39 labels | OR52A1 |
| Chromosomal location | 11:5,151,434-5,152,369 (-) |
| Cluster | 11@5 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR52A5 | 74.84% | 310 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR52A1BP | 83% | 309 |
| Mouse | Or52a24 | 75% | 309 |
| Rat | Or52a20 | 74% | 313 |
| Cow | OR52A1E | 83% | 312 |
| Cow | OR52A1C | 83% | 312 |
| Cow | OR52A1F | 82% | 312 |
| Orang | OR52A5 | 75% | 306 |
| Horse | OR52A1J | 85% | 312 |
| Horse | OR52A1K | 85% | 312 |
| Horse | OR52A1I | 84% | 312 |
| Chimp | OR52A5 | 74% | 310 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB463975 |
| GNF Atlas2 | 221329_at |
Sequence information
| Nucleotide sequence |
ATGTCCATTTCCAACATCACAGTCTACATGCCCTCTGTGTTGACACTAGTAGGGATCCCA GGCCTAGAATCTGTGCAGTGCTGGATTGGGATTCCATTCTGTGCCATTTATCTCATTGCT ATGATTGGAAATTCCTTGCTTCTGAGCATCATCAAATCTGAGCGCAGTCTCCATGAGCCC TTGTACATTTTCTTAGGCATGCTAGGAGCCACAGACATTGCACTTGCTAGCAGCATTATG CCAAAGATGCTTGGAATATTCTGGTTTAATGTGCCTGAAATCTATTTTGATTCCTGCTTG CTTCAAATGTGGTTCATCCACACATTGCAGGGTATAGAGTCAGGCATCCTTGTGGCCATG GCCCTGGACCGTTATGTGGCCATCTGTTATCCACTAAGACATGCCAACATCTTCACCCAC CAGCTTGTCATTCAGATAGGAACTATGGTCGTACTCAGGGCTGCTATTCTTGTAGCCCCA TGCCTAGTACTGATAAAGTGCCGGTTTCAATTTTATCACACAACAGTCATCTCCCACTCC TACTGTGAGCATATGGCCATTGTGAAACTAGCAGCAGCAAATGTTCAAGTCAACAAAATC TATGGTTTGTTTGTGGCCTTCACTGTAGCAGGATTTGACCTCACATTCATCACATTGTCC TACATCCAGATATTTATCACAGTTTTTCGTTTGCCCCAGAAGGAGGCTAGGTTTAAAGCA TTCAATACCTGCATTGCTCACATCTGTGTCTTCCTCCAGTTCTACCTCCTTGCCTTCTTC TCCTTCTTCACACATAGGTTTGGGTCTCACATCTCCCCTTATATCCATATTCTCTTTTCT AGCATTTACTTGCTGGTCCCTCCATTTCTCAATCCACTTGTCTATGGTGCAAAGACCACA CAGATTCGCATTCATGTGGTAAAAATGTTCTGTTCA |
| Conceptual translation |
MSISNITVYMPSVLTLVGIPGLESVQCWIGIPFCAIYLIAMIGNSLLLSIIKSERSLHEP LYIFLGMLGATDIALASSIMPKMLGIFWFNVPEIYFDSCLLQMWFIHTLQGIESGILVAM ALDRYVAICYPLRHANIFTHQLVIQIGTMVVLRAAILVAPCLVLIKCRFQFYHTTVISHS YCEHMAIVKLAAANVQVNKIYGLFVAFTVAGFDLTFITLSYIQIFITVFRLPQKEARFKA FNTCIAHICVFLQFYLLAFFSFFTHRFGSHISPYIHILFSSIYLLVPPFLNPLVYGAKTT QIRIHVVKMFCS Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 5,173,090 | 5,173,089 | Ins(1) | -/A | rs36060295 (DbSNP) | |
| 11 | 5,172,786 | 5,172,786 | NS | A/G | S/P | rs10768611 (DbSNP) |
| 11 | 5,151,919 | 5,151,919 | NS | C/A | V/L | 1000GP (CEU, CHBJPT) |
| 11 | 5,151,556 | 5,151,556 | NS | A/G | S/P | 1000GP (CEU, CHBJPT) |
| 11 | 100 | -100 | SYN | G/A | R/R | 1000GP (YRI) |
| 11 | 100 | -100 | NS | A/G | S/P | 1000GP (YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| V151L | R124H | W88* | G21D | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | V | R | W | G | 94.39 | 0.095 |
| 2 | L | R | W | G | 5.38 | 0.095 |
| 3 | V | R | W | D | 0.08 | 0.095 |
| 4 | V | H | W | G | 0.08 | 0.652 |
| 5 | V | R | * | G | 0.08 | 1.200 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR52A1.aApr07-unspliced | main_exon | 3UTR | chr11 | 5,151,431 | 5,151,434 | - |
| CDS | chr11 | 5,151,434 | 5,152,369 | - | ||