OR52E2 Olfactory Receptor
| Gene Symbol | OR52E21 (View this gene in GeneCards) |
| Family | 52 |
| Subfamily | E |
| Pseudogene | No |
| CORP pseudogene probability score | 0.62 (pseudogene) |
| Aliases | HsOR11.3.44, ORL3372 |
| External Ids | HGNC: 14769 GeneBank: AB065800, NM_001005164 ORDB: ORL3372 |
| Build #39 labels | OR52E2 |
| Chromosomal location | 11:5,058,653-5,059,627 (-) |
| Cluster | 11@5 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR52E3P | 84.24% | 311 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR52E2B | 86% | 311 |
| Mouse | Or52e2 | 84% | 317 |
| Mouse | Or52e3 | 83% | 311 |
| Rat | Or52e2 | 83% | 317 |
| Rat | Or52e3 | 84% | 311 |
| Cow | OR52E2P | 84% | 314 |
| Cow | OR52E3 | 84% | 311 |
| Orang | OR52E3 | 83% | 311 |
| Horse | OR52E3 | 83% | 311 |
| Chimp | OR52E3 | 85% | 311 |
Sequence information
| Nucleotide sequence |
ATGTTCCTTCCCAATGACACCCAGTTTCACCCCTCCTCCTTCCTGTTGCTGGGGATCCCA GGACTAGAAACACTTCACATCTGGATCGGCTTTCCCTTCTGTGCTGTGTACATGATCGCA CTCATAGGGAACTTCACTATTCTACTTGTGATCAAGACTGACAGCAGCCTACACCAGCCC ATGTTCTACTTCCTGGCCATGTTGGCCACCACTGATGTGGGTCTCTCAACAGCTACCATC CCTAAGATGCTTGGAATCTTCTGGATCAACCTCAGAGGGATCATCTTTGAAGCCTGCCTC ACCCAGATGTTTTTTATCCACAACTTCACACTTATGGAGTCAGCAGTCCTTGTGGCAATG GCTTATGACAGCTATGTGGCCATCTGCAATCCACTCCAATATAGCGCCATCCTCACCAAC AAGGTTGTTTCTGTGATTGGTCTTGGTGTGTTTGTGAGGGCTTTAATTTTCGTCATTCCC TCTATACTTCTTATATTGCGGTTGCCCTTCTGTGGGAATCATGTAATTCCCCACACCTAC TGTGAGCACATGGGTCTTGCTCATCTATCTTGTGCCAGCATCAAAATCAATATTATTTAT GGTTTATGTGCCATTTGTAATCTAGTGTTTGACATCACAGTCATTGCCCTTTCTTATGTG CATATTCTTTGTGCTGTTTTCCGTCTTCCTACTCATGAAGCCCGACTCAAGTCCCTCAGC ACATGTGGTTCACATGTGTGTGTAATCCTTGCCTTCTATACACCAGCCCTCTTTTCCTTT ATGACTCATCGCTTTGGCCGAAATGTGCCCCGCTATATCCATATACTCCTAGCCAATCTC TATGTTGTGGTGCCACCAATGCTCAATCCTGTCATATATGGAGTCAGAACCAAGCAGATC TATAAATGTGTGAAGAAAATATTATTGCAGGAACAAGGAATGGAAAAGGAAGAGTACCTA ATACATACGAGGTTC |
| Conceptual translation |
MFLPNDTQFHPSSFLLLGIPGLETLHIWIGFPFCAVYMIALIGNFTILLVIKTDSSLHQP MFYFLAMLATTDVGLSTATIPKMLGIFWINLRGIIFEACLTQMFFIHNFTLMESAVLVAM AYDSYVAICNPLQYSAILTNKVVSVIGLGVFVRALIFVIPSILLILRLPFCGNHVIPHTY CEHMGLAHLSCASIKINIIYGLCAICNLVFDITVIALSYVHILCAVFRLPTHEARLKSLS TCGSHVCVILAFYTPALFSFMTHRFGRNVPRYIHILLANLYVVVPPMLNPVIYGVRTKQI YKCVKKILLQEQGMEKEEYLIHTRF Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 5,080,068 | 5,080,068 | NS | A/G | C/R | rs2500052 (DbSNP) |
| 11 | 5,080,181 | 5,080,181 | NS | A/G | V/A | rs72873928 (DbSNP) |
| 11 | 5,080,359 | 5,080,359 | NS | A/G | W/R | rs11035396 (DbSNP) |
| 11 | 5,080,844 | 5,080,844 | NS | C/T | S/N | rs16909440 (DbSNP) |
| 11 | 5,080,337 | 5,080,337 | NS | C/T | R/H | rs61746343 (DbSNP) |
| 11 | 5,079,984 | 5,079,984 | NS | T/C | I/V | rs61995745 (DbSNP) |
| 11 | 5,080,234 | 5,080,234 | SYN | C/T | L/L | rs2445333 (DbSNP) |
| 11 | 5,079,946 | 5,079,946 | SYN | C/T | V/V | rs2445332 (DbSNP) |
| 11 | 5,080,591 | 5,080,591 | SYN | G/T | I/I | rs12576484 (DbSNP) |
| 11 | 5,058,951 | 5,058,951 | NS | A/G | V/A | 1000GP (CEU) |
| 11 | 5,058,838 | 5,058,838 | NS | G/A | R/C | 1000GP (CEU, CHBJPT) |
| 11 | 5,059,004 | 5,059,004 | SYN | T/C | L/L | 1000GP (CEU, CHBJPT) |
| 11 | 5,059,107 | 5,059,107 | NS | T/C | H/R | 1000GP (CEU, CHBJPT) |
| 11 | 5,059,614 | 5,059,614 | NS | T/C | N/S | 1000GP (CEU, CHBJPT) |
| 11 | 5,059,503 | 5,059,503 | NS | A/G | I/T | 1000GP (CEU) |
| 11 | 5,058,716 | 5,058,716 | SYN | C/T | V/V | 1000GP (CEU, CHBJPT) |
| 11 | 5,059,129 | 5,059,129 | NS | G/A | R/W | 1000GP (CEU, CHBJPT) |
| 11 | 100 | -100 | SYN | C/T | V/V | 1000GP (YRI, YRI, YRI) |
| 11 | 100 | -100 | NS | G/A | R/C | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 4,907,893 | 5,135,331 | CopyNumber | Variation_3835 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| I292V | R264C | M261V | V226A | H174R | R167W | G147D | A69T | N5S | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | I | R | M | V | H | R | G | A | S | 30.18 | 0.670 |
| 2 | I | C | M | V | H | R | G | A | N | 24.58 | 0.670 |
| 3 | I | C | M | V | R | R | G | A | N | 19.35 | 0.670 |
| 4 | I | R | M | V | H | R | G | A | N | 11.98 | 0.670 |
| 5 | I | R | M | V | H | W | G | A | N | 9.29 | 0.670 |
| 6 | V | C | M | V | H | R | G | A | N | 1.61 | 0.670 |
| 7 | I | C | V | V | H | R | G | A | N | 1.00 | 0.670 |
| 8 | I | C | M | A | R | R | G | A | N | 0.77 | 0.872 |
| 9 | I | R | M | V | H | R | D | A | S | 0.61 | 0.670 |
| 10 | I | C | M | V | R | R | G | T | N | 0.31 | 0.134 |
| 11 | I | C | M | V | H | R | G | A | S | 0.15 | 0.670 |
| 12 | I | C | V | V | R | R | G | A | N | 0.08 | 0.670 |
| 13 | I | C | M | V | R | R | G | A | S | 0.08 | 0.670 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR52E2.aApr07-unspliced | main_exon | 3UTR | chr11 | 5,058,650 | 5,058,653 | - |
| CDS | chr11 | 5,058,653 | 5,059,627 | - | ||