OR52E5 Olfactory Receptor
| Gene Symbol | OR52E51 (View this gene in GeneCards) |
| Family | 52 |
| Subfamily | E |
| Pseudogene | No |
| CORP pseudogene probability score | 0.92 (pseudogene) |
| Aliases | OR11-56, HsOR11.3.88, ORL3294 |
| External Ids | HGNC: 15214 GeneBank: AB065536, BK004566, NM_001005166 ORDB: ORL3294 |
| Build #39 labels | OR52E5 |
| Chromosomal location | 11:5,900,777-5,901,757 (+) |
| Cluster | 11@6 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR52E2 | 67.86% | 308 |
| OR52E4 | 68.08% | 307 |
| OR52E8 | 67.75% | 307 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR52E1 | 69% | 312 |
| Mouse | Or52e5 | 87% | 311 |
| Rat | Or52e5 | 87% | 311 |
| Rat | Or52e5b | 87% | 311 |
| Cow | OR52E1 | 69% | 312 |
| Orang | OR52E3 | 65% | 311 |
| Horse | OR52E20P | 70% | 308 |
| Chimp | OR52E4 | 68% | 308 |
Sequence information
| Nucleotide sequence |
ATGCTTCATACCAACAATACACAGTTTCACCCTTCCACCTTCCTCGTAGTGGGGGTCCCA GGGCTGGAAGATGTGCATGTATGGATTGGCTTCCCCTTCTTTGCAGTGTATCTAACAGCC CTTCTAGGGAACATCATTATCCTGTTTGTGATACAGACTGAACAGAGCCTCCACCAACCC ATGTTTTACTTCCTAGCCATGTTGGCCGGCACTGATCTGGGCTTGTCTACAGCAACCATC CCCAAGATGCTGGGAATTTTCTGGTTTAATCTTGGAGAGATTGCATTTGGTGCCTGCATC ACACAGATGTATACCATTCATATATGCACTGGCCTGGAGTCTGTGGTACTGACAGTCACG GGCATAGATCGCTATATTGCCATCTGCAACCCCCTGAGATATAGCATGATCCTTACCAAC AAGGTAATAGCCATTCTGGGCATAGTCATCATTGTCAGGACTTTGGTATTTGTGACTCCA TTCACATTTCTCATCCTGAGATTGCCTTTCTGTGGTGTCCGGATTATCCCTCATACCTAT TGTGAACACATGGGCTTGGCAAAGTTAGCTTGTGCCAGTATTAATGTTATATATGGATTG ATTGCCTTCTCAGTGGGATACATTGACATTTCTGTGATTGGATTTTCCTATGTCCAGATC CTCCGAGCTGTCTTCCATCTCCCAGCCTGGGATGCCCGGCCTAAGGCACTCAGCACATGT GGCTCTCACGTCTGTGTTATGTTGGCTTTCTACCTGCCAGCCCTCTTTTCCTTCATGACA CACCGCTTTGGCCACAACATCCCTCATTACATCCACATTCTTCTGGCCAATCTGTATGTG GTTTTTCCCCCTGCTCTTAACTCTGTTATCTATGGGGTCAAAACAAAACAGATACGAGAG CAGGTACTTAGGATACTCAACCCTAAAAGCTTTTGGCATTTTGACCCCAAGAGGATCTTC CACAACAATTCAGTTAGACAA |
| Conceptual translation |
MLHTNNTQFHPSTFLVVGVPGLEDVHVWIGFPFFAVYLTALLGNIIILFVIQTEQSLHQP MFYFLAMLAGTDLGLSTATIPKMLGIFWFNLGEIAFGACITQMYTIHICTGLESVVLTVT GIDRYIAICNPLRYSMILTNKVIAILGIVIIVRTLVFVTPFTFLILRLPFCGVRIIPHTY CEHMGLAKLACASINVIYGLIAFSVGYIDISVIGFSYVQILRAVFHLPAWDARPKALSTC GSHVCVMLAFYLPALFSFMTHRFGHNIPHYIHILLANLYVVFPPALNSVIYGVKTKQIRE QVLRILNPKSFWHFDPKRIFHNNSVRQ Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 5,922,632 | 5,922,632 | NS | A/G | D/G | rs16926732 (DbSNP) |
| 11 | 5,922,707 | 5,922,707 | NS | C/T | P/L | rs7106300 (DbSNP) |
| 11 | 5,922,500 | 5,922,500 | NS | C/T | T/I | rs17234326 (DbSNP) |
| 11 | 5,922,366 | 5,922,366 | SYN | A/G | T/T | rs16926729 (DbSNP) |
| 11 | 5,922,222 | 5,922,222 | SYN | C/T | D/D | rs10160336 (DbSNP) |
| 11 | 5,901,063 | 5,901,063 | NS | T/G | F/C | 1000GP (CEU) |
| 11 | 5,900,992 | 5,900,992 | SYN | T/C | D/D | 1000GP (CEU, CHBJPT) |
| 11 | 5,901,402 | 5,901,402 | NS | A/G | D/G | 1000GP (CEU, CHBJPT) |
| 11 | 5,901,477 | 5,901,477 | NS | C/T | P/L | 1000GP (CEU, CHBJPT) |
| 11 | 5,901,270 | 5,901,270 | NS | T/C | I/T | 1000GP (CEU, CHBJPT) |
| 11 | 5,901,136 | 5,901,136 | SYN | G/A | T/T | 1000GP (CHBJPT) |
| 11 | 100 | -100 | SYN | C/T | A/A | 1000GP (YRI, YRI, YRI) |
| 11 | 100 | -100 | NS | C/A | Q/K | 1000GP (YRI, YRI, YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 5,868,055 | 6,007,613 | CopyNumber | Variation_2903 (DGV) |
| 11 | 5,730,377 | 5,970,717 | CopyNumber | Variation_3836 (DGV) |
| 11 | 5,921,129 | 5,963,801 | CopyNumber | Variation_6928 (DGV) |
| 11 | 5,885,711 | 5,969,185 | CopyNumber | Variation_8676 (DGV) |
| 11 | 5,885,711 | 5,934,044 | CopyNumber | Variation_8677 (DGV) |
| 11 | 5,899,885 | 5,935,103 | CopyNumber | Variation_9650 (DGV), Variation_48860 (DGV), Variation_53917 (DGV) |
| 11 | 5,899,885 | 5,935,102 | CopyNumber | Variation_29603 (DGV) |
| 11 | 5,883,376 | 5,935,626 | CopyNumber | Variation_30541 (DGV) |
| 11 | 5,505,764 | 6,194,475 | CopyNumber | Variation_34458 (DGV) |
| 11 | 5,885,709 | 5,935,510 | CopyNumber | Variation_37668 (DGV) |
| 11 | 5,875,867 | 5,935,103 | CopyNumber | Variation_48859 (DGV) |
| 11 | 5,899,885 | 5,959,757 | CopyNumber | Variation_53792 (DGV) |
| 11 | 5,871,831 | 5,935,103 | CopyNumber | Variation_53856 (DGV) |
| 11 | 5,921,907 | 5,924,987 | CopyNumber | #135 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| F96C | Q102K | I143V | I165T | A192D | D209G | P234L | R262H | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | F | Q | I | I | A | D | L | R | 76.50 | 0.895 |
| 2 | F | Q | I | T | A | D | L | R | 11.52 | 0.895 |
| 3 | F | Q | I | I | A | D | P | R | 5.76 | 0.895 |
| 4 | F | Q | I | T | A | G | L | R | 2.00 | 0.791 |
| 5 | F | Q | V | I | A | D | L | R | 1.38 | 0.895 |
| 6 | C | Q | I | I | A | D | P | R | 1.08 | 0.895 |
| 7 | F | Q | I | I | A | D | L | H | 1.08 | 0.895 |
| 8 | F | K | I | I | A | D | L | R | 0.54 | 0.984 |
| 9 | F | Q | I | I | A | G | L | R | 0.08 | 0.791 |
| 10 | F | Q | I | I | D | D | L | R | 0.08 | 0.895 |