OR52I1 Olfactory Receptor
| Gene Symbol | OR52I11 (View this gene in GeneCards) |
| Family | 52 |
| Subfamily | I |
| Pseudogene | No |
| CORP pseudogene probability score | 0.34 (functional) |
| Aliases | OR11-13, HsOR11.3.12, ORL3428 |
| External Ids | HGNC: 15220 GeneBank: AB065788, BK004371, NM_001005169 ORDB: ORL3428 |
| Build #39 labels | OR52I1 |
| Chromosomal location | 11:4,594,066-4,595,010 (+) |
| Cluster | 11@5 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR52I2 | 95.06% | 324 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR52E22 | 48% | 305 |
| Mouse | Or52i2 | 78% | 324 |
| Rat | Or52b2 | 47% | 312 |
| Cow | OR52I1B | 81% | 324 |
| Orang | OR52I2 | 92% | 324 |
| Orang | OR52I1C | 91% | 324 |
| Horse | OR52I2 | 81% | 324 |
| Chimp | OR52I1B | 95% | 324 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB463977 |
| GNF Atlas2 | gnf1h10649_at |
Sequence information
| Nucleotide sequence |
ATGGAAACCCCTGCCTCCTTCCTCCTTGTGGGTATCCCAGGACTGCAATCTTCACATCTT TGGCTGGCTATCTCACTGAGTGCCATGTACATCACAGCCCTGTTAGGAAACACCCTCATC GTGACTGCAATCTGGATGGATTCCACTCGGCATGAGCCCATGTATTGCTTTCTGTGTGTT CTGGCTGCTGTGGACATTGTTATGGCCTCCTCCGTGGTACCCAAGATGGTGAGCATCTTC TGCTCGGGAGACAGCTCCATCAGCTTTAGTGCTTGTTTCACTCAGATGTTTTTTGTCCAC TTAGCCACAGCTGTGGAGACGGGGCTGCTGCTGACCATGGCTTTTGACCGCTATGTAGCC ATCTGCAAGCCTCTACACTACAAGAGAATTCTCACGCCTCAAGTGATGCTGGGAATGAGT ATGGCCGTCACCATCAGAGCTGTCACATTCATGACTCCACTGAGTTGGATGATGAATCAT CTACCTTTCTGTGGCTCCAATGTGGTTGTCCACTCCTACTGTAAGCACATAGCTTTGGCC AGGTTAGCATGTGCTGACCCCGTGCCCAGCAGTCTCTACAGTCTGATTGGTTCCTCTCTT ATGGTGGGCTCTGATGTGGCCTTCATTGCTGCCTCCTATATCTTAATTCTCAGGGCAGTA TTTGATCTCTCCTCAAAGACTGCTCAGTTGAAAGCATTAAGCACATGTGGCTCCCATGTG GGGGTTATGGCTTTGTACTATCTACCTGGGATGGCATCCATCTATGCGGCCTGGTTGGGG CAGGATATAGTGCCCTTGCACACCCAAGTGCTGCTAGCTGACCTGTACGTGATCATCCCA GCCACTTTAAATCCCATCATCTATGGCATGAGGACCAAACAATTGCTGGAGGGAATATGG AGTTATCTGATGCACTTCCTCTTTGACCACTCCAACCTGGGTTCA |
| Conceptual translation |
MLGPAYNHTMETPASFLLVGIPGLQSSHLWLAISLSAMYITALLGNTLIVTAIWMDSTRH EPMYCFLCVLAAVDIVMASSVVPKMVSIFCSGDSSISFSACFTQMFFVHLATAVETGLLL TMAFDRYVAICKPLHYKRILTPQVMLGMSMAVTIRAVTFMTPLSWMMNHLPFCGSNVVVH SYCKHIALARLACADPVPSSLYSLIGSSLMVGSDVAFIAASYILILRAVFDLSSKTAQLK ALSTCGSHVGVMALYYLPGMASIYAAWLGQDIVPLHTQVLLADLYVIIPATLNPIIYGMR TKQLLEGIWSYLMHFLFDHSNLGS Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 4,615,987 | 4,615,987 | NS | A/C | K/T | rs1876025 (DbSNP) |
| 11 | 4,615,857 | 4,615,857 | NS | A/G | M/V | rs62622512 (DbSNP) |
| 11 | 4,616,062 | 4,616,062 | NS | C/T | A/V | rs61997187 (DbSNP) |
| 11 | 4,615,423 | 4,615,423 | NS | C/T | A/V | rs61745326 (DbSNP) |
| 11 | 4,615,390 | 4,615,390 | NS | C/T | T/I | rs2010722 (DbSNP) |
| 11 | 4,616,119 | 4,616,119 | NS | C/T | P/L | rs61997192 (DbSNP) |
| 11 | 4,615,616 | 4,615,616 | SYN | A/G | T/T | rs56095500 (DbSNP) |
| 11 | 4,615,508 | 4,615,508 | SYN | C/G | S/S | rs2010719 (DbSNP) |
| 11 | 4,594,889 | 4,594,889 | NS | T/C | L/P | 1000GP (CEU) |
| 11 | 100 | -100 | NS | C/T | T/I | 1000GP (YRI, YRI) |
| 11 | 100 | -100 | SYN | C/G | S/S | 1000GP (YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| T66I | A77V | M192V | N193S | C208R | K209E | K265T | A290V | L309P | N346S | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | I | A | M | N | C | K | K | A | L | N | 78.96 | 0.748 |
| 2 | T | A | M | N | C | K | K | A | L | N | 11.06 | 0.748 |
| 3 | I | A | M | N | C | K | K | V | L | N | 3.76 | 0.748 |
| 4 | I | A | M | N | C | K | K | V | P | N | 2.92 | 0.748 |
| 5 | T | A | V | S | C | K | K | A | L | N | 0.92 | 0.748 |
| 6 | I | A | M | N | C | K | T | A | L | N | 0.92 | 0.748 |
| 7 | I | V | M | N | C | K | K | V | L | N | 0.38 | 0.748 |
| 8 | T | A | V | S | C | E | K | A | L | N | 0.23 | 0.748 |
| 9 | I | A | M | N | C | K | K | A | P | N | 0.15 | 0.748 |
| 10 | T | A | M | N | C | K | K | A | L | S | 0.15 | 0.748 |
| 11 | T | A | M | N | C | K | K | V | L | N | 0.15 | 0.748 |
| 12 | I | A | M | N | C | E | K | A | L | N | 0.08 | 0.748 |
| 13 | T | A | V | N | C | E | K | A | L | N | 0.08 | 0.748 |
| 14 | I | A | M | N | R | K | K | A | L | N | 0.08 | 0.748 |
| 15 | T | A | V | S | C | K | K | A | L | S | 0.08 | 0.748 |
| 16 | T | A | V | N | C | K | K | A | L | N | 0.08 | 0.748 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR52I1.aApr07-unspliced | main_exon | 5UTR | chr11 | 4,594,039 | 4,594,066 | + |
| CDS | chr11 | 4,594,066 | 4,595,010 | + | ||
| 3UTR | chr11 | 4,595,010 | 4,595,013 | + | ||