OR52I2 Olfactory Receptor
| Gene Symbol | OR52I21 (View this gene in GeneCards) |
| Family | 52 |
| Subfamily | I |
| Pseudogene | No |
| CORP pseudogene probability score | 0.34 (functional) |
| Aliases | OR11-12, HsOR11.3.11, ORL3429 |
| External Ids | HGNC: 15221 GeneBank: AB065522, BK004264, NM_001005170 ORDB: ORL3429 |
| Build #39 labels | OR52I2 |
| Chromosomal location | 11:4,586,918-4,587,862 (+) |
| Cluster | 11@5 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR52I1 | 95.06% | 324 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR52I1 | 83% | 324 |
| Mouse | Or52i2 | 80% | 324 |
| Rat | Or52e5b | 48% | 303 |
| Cow | OR52I1B | 82% | 324 |
| Cow | OR52I1 | 81% | 324 |
| Cow | OR52I11 | 81% | 324 |
| Orang | OR52I1 | 95% | 324 |
| Horse | OR52I1 | 82% | 324 |
| Horse | OR52I12 | 81% | 324 |
| Horse | OR52I13 | 81% | 315 |
| Chimp | OR52I1B | 97% | 324 |
| Chimp | OR52I1 | 96% | 324 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC151144 |
Sequence information
| Nucleotide sequence |
ATGGAAACCCCTGCCTCCTTCCTCCTTGTGGGTATCCCAGGACTGCAATCTTCACATCTT TGGCTGGCTATCTCACTGAGTGCCATGTACATCATAGCCCTGTTAGGAAACACCATCATC GTGACTGCAATCTGGATGGATTCCACTCGGCATGAGCCCATGTATTGCTTTCTGTGTGTT CTGGCTGCTGTGGACATTGTTATGGCCTCCTCGGTGGTACCCAAGATGGTGAGCATCTTC TGCTCAGGAGACAGCTCAATCAGCTTTAGTGCTTGTTTCACTCAGATGTTTTTTGTCCAC TTAGCCACAGCTGTGGAGACGGGGCTGCTGCTGACCATGGCTTTTGACCGCTATGTAGCC ATCTGCAAGCCTCTACACTACAAGAGAATTCTCACGCCTCAAGTGATGCTGGGAATGAGT ATGGCCATCACCATCAGAGCTATCATAGCCATAACTCCACTGAGTTGGATGGTGAGTCAT CTACCTTTCTGTGGCTCCAATGTGGTTGTCCACTCCTACTGTGAGCACATAGCTTTGGCC AGGTTAGCATGTGCTGACCCCGTGCCCAGCAGTCTCTACAGTCTGATTGGTTCCTCTCTT ATGGTGGGCTCTGATGTGGCCTTCATTGCTGCCTCCTATATCTTAATTCTCAAGGCAGTA TTTGGTCTCTCCTCAAAGACTGCTCAGTTGAAAGCATTAAGCACATGTGGCTCCCATGTG GGGGTTATGGCTTTGTACTATCTACCTGGGATGGCATCCATCTATGCGGCCTGGTTGGGG CAGGATGTAGTGCCCTTGCACACCCAAGTCCTGCTAGCTGACCTGTACGTGATCATCCCA GCCACCTTAAATCCCATCATCTATGGCATGAGGACCAAACAACTGCGGGAGAGAATATGG AGTTATCTGATGCATGTCCTCTTTGACCATTCCAACCTGGGTTCA |
| Conceptual translation |
MLGPAYNHTMETPASFLLVGIPGLQSSHLWLAISLSAMYIIALLGNTIIVTAIWMDSTRH EPMYCFLCVLAAVDIVMASSVVPKMVSIFCSGDSSISFSACFTQMFFVHLATAVETGLLL TMAFDRYVAICKPLHYKRILTPQVMLGMSMAITIRAIIAITPLSWMVSHLPFCGSNVVVH SYCEHIALARLACADPVPSSLYSLIGSSLMVGSDVAFIAASYILILKAVFGLSSKTAQLK ALSTCGSHVGVMALYYLPGMASIYAAWLGQDVVPLHTQVLLADLYVIIPATLNPIIYGMR TKQLRERIWSYLMHVLFDHSNLGS Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 4,608,262 | 4,608,262 | NS | A/C | I/L | rs12793957 (DbSNP) |
| 11 | 4,608,589 | 4,608,589 | NS | A/G | I/V | rs7947432 (DbSNP) |
| 11 | 4,608,574 | 4,608,574 | NS | A/G | I/V | rs7947426 (DbSNP) |
| 11 | 4,608,242 | 4,608,242 | NS | C/T | T/I | rs61744242 (DbSNP) |
| 11 | 4,608,542 | 4,608,542 | NS | T/C | M/T | rs1847632 (DbSNP) |
| 11 | 4,608,393 | 4,608,393 | SYN | A/G | S/S | rs56002758 (DbSNP) |
| 11 | 4,608,405 | 4,608,405 | SYN | C/A | S/S | rs2201338 (DbSNP) |
| 11 | 4,608,726 | 4,608,726 | SYN | C/T | Y/Y | rs55804480 (DbSNP) |
| 11 | 4,587,032 | 4,587,032 | NS | A/C | I/L | 1000GP (CEU) |
| 11 | 4,587,012 | 4,587,012 | NS | T/C | I/T | 1000GP (CEU) |
| 11 | 100 | -100 | NS | T/C | I/T | 1000GP (YRI, YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| I67T | I74L | D119G | T167M | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | I | I | D | T | 45.55 | 0.768 |
| 2 | I | I | D | M | 37.17 | 0.768 |
| 3 | I | L | D | T | 13.44 | 0.768 |
| 4 | T | I | D | T | 3.38 | 0.768 |
| 5 | I | L | D | M | 0.23 | 0.768 |
| 6 | T | L | D | T | 0.15 | 0.768 |
| 7 | I | I | G | T | 0.08 | 0.768 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR52I2.aApr07-unspliced | main_exon | 5UTR | chr11 | 4,586,813 | 4,586,918 | + |
| CDS | chr11 | 4,586,918 | 4,587,862 | + | ||
| 3UTR | chr11 | 4,587,862 | 4,587,865 | + | ||