OR52K1 Olfactory Receptor
| Gene Symbol | OR52K11 (View this gene in GeneCards) |
| Family | 52 |
| Subfamily | K |
| Pseudogene | No |
| CORP pseudogene probability score | 0.04 (functional) |
| Aliases | OR11-8, HsOR11.3.8, ORL3450 |
| External Ids | HGNC: 15222 GeneBank: AB065790, BK004257, NM_001005171 ORDB: ORL3450 |
| Build #39 labels | OR52K1 |
| Chromosomal location | 11:4,488,901-4,489,842 (+) |
| Cluster | 11@5 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR52K2 | 90.76% | 314 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR52K1B | 90% | 313 |
| Mouse | Or52k2 | 88% | 314 |
| Rat | Or52k1 | 90% | 310 |
| Rat | Or52k2 | 87% | 314 |
| Cow | OR52K2 | 89% | 314 |
| Orang | OR52K2 | 90% | 314 |
| Horse | OR52P2 | 55% | 308 |
| Chimp | OR52K1P | 97% | 314 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC137059 |
| GNF Atlas2 | gnf1h10682_x_at |
| GNF Atlas2 | gnf1h10683_at |
Sequence information
| Nucleotide sequence |
ATGCTTCCCTCTAATATCACCTCAACACATCCAGCTGTCTTTTTGTTGGTAGGAATTCCT GGTTTGGAACACCTGCATGCCTGGATCTCCATCCCCTTCTGCTTTGCTTATACTCTGGCC CTGCTAGGCAACTGTACCCTTCTCTTCATTATCCAGGCTGATGCAGCCCTCCATGAACCC ATGTACCTCTTTCTGGCCATGTTGGCAACCATTGACTTGGTTCTTTCTTCTACAACGCTG CCCAAAATGCTTGCCATATTCTGGTTCAGGGATCAGGAGATCAACTTCTTTGCCTGTCTG GTCCAGATGTTCTTCCTTCACTCCTTCTCCATCATGGAGTCAGCAGTGCTGCTGGCCATG GCCTTTGACCGCTATGTGGCCATCTGCAAGCCATTGCACTACACGACGGTCCTGACTGGG TCCCTCATCACCAAGATTGGCATGGCTGCTGTGGCCCGGGCTGTGACACTAATGACTCCA CTCCCCTTCCTGCTCAGACGCTTCCACTACTGCCGAGGCCCAGTGATTGCCCATTGCTAC TGTGAACACATGGCTGTGGTAAGGCTGGCGTGTGGGGACACTAGCTTCAACAATATCTAT GGCATTGCTGTGGCCATGTTTATTGTGGTGTTGGACCTGCTCTTTGTTATCCTGTCTTAT GTCTTCATCCTTCAGGCAGTTCTCCAGCTTGCCTCTCAGGAGGCCCGCTACAAGGCATTT GGGACATGTGTGTCTCACATAGGTGCCATCCTGTCCACCTACACTCCAGTAGTCATCTCT TCAGTCATGCACCGTGTAGCCCGCCATGCTGCCCCTCGTGTCCACATACTCCTTGCTATT TTCTATCTCCTTTTCCCACCCATGGTCAATCCTATCATATATGGAGTCAAGACCAAGCAG ATTCGTGAGTATGTGCTCAGTCTATTCCAGAGAAAGAACATG |
| Conceptual translation |
MLPSNITSTHPAVFLLVGIPGLEHLHAWISIPFCFAYTLALLGNCTLLFIIQADAALHEP MYLFLAMLATIDLVLSSTTLPKMLAIFWFRDQEINFFACLVQMFFLHSFSIMESAVLLAM AFDRYVAICKPLHYTTVLTGSLITKIGMAAVARAVTLMTPLPFLLRRFHYCRGPVIAHCY CEHMAVVRLACGDTSFNNIYGIAVAMFIVVLDLLFVILSYVFILQAVLQLASQEARYKAF GTCVSHIGAILSTYTPVVISSVMHRVARHAAPRVHILLAIFYLLFPPMVNPIIYGVKTKQ IREYVLSLFQRKNM Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 4,510,285 | 4,510,285 | NS | G/A | R/Q | rs96489 (DbSNP) |
| 11 | 4,510,587 | 4,510,587 | NS | T/C | W/R | rs331510 (DbSNP) |
| 11 | 4,510,553 | 4,510,553 | SYN | C/T | S/S | rs3889581 (DbSNP) |
| 11 | 4,489,055 | 4,489,055 | NS | A/G | Q/R | 1000GP (CEU, CHBJPT) |
| 11 | 100 | -100 | NS | A/G | Q/R | 1000GP (YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 4,510,285 | 4,562,458 | CopyNumber | Variation_2899 (DGV) |
| 11 | 4,055,945 | 4,510,188 | CopyNumber | Variation_3834 (DGV) |
| 11 | 4,510,284 | 4,562,394 | CopyNumber | Variation_9172 (DGV) |
| 11 | 4,510,137 | 4,562,393 | CopyNumber | Variation_38231 (DGV) |
| 11 | 4,510,031 | 4,513,072 | Deletion, CopyNumber | #259 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| L25P | Q52R | I71T | % Freq | CORP | |
|---|---|---|---|---|---|
| 1 | L | Q | I | 63.13 | 0.052 |
| 2 | L | R | I | 35.87 | 0.052 |
| 3 | P | R | I | 0.46 | 0.052 |
| 4 | L | R | T | 0.46 | 0.052 |
| 5 | P | Q | I | 0.08 | 0.052 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR52K1.aApr07-unspliced | main_exon | CDS | chr11 | 4,488,901 | 4,489,842 | + |
| 3UTR | chr11 | 4,489,842 | 4,489,845 | + | ||