OR52M1 Olfactory Receptor
| Gene Symbol | OR52M11 (View this gene in GeneCards) |
| Family | 52 |
| Subfamily | M |
| Pseudogene | No |
| CORP pseudogene probability score | 0.12 (functional) |
| Aliases | OR11-11, HsOR11.3.10 |
| External Ids | HGNC: 15225 GeneBank: AB065789, AF546574-AF546587, BK004372, NM_001004137 |
| Build #39 labels | OR52M1 |
| Chromosomal location | 11:4,545,191-4,546,141 (+) |
| Cluster | 11@5 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR52M2P | 78.12% | 320 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR52M2 | 81% | 309 |
| Mouse | Or52m1 | 90% | 317 |
| Rat | Or52m1 | 91% | 317 |
| Cow | OR52M2 | 81% | 309 |
| Orang | OR52M1P | 85% | 303 |
| Horse | OR52M2 | 80% | 317 |
| Chimp | OR52P1 | 55% | 298 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB463978 |
| GNF Atlas2 | gnf1h10684_at |
Sequence information
| Nucleotide sequence |
ATGCTCACTTTTCATAATGTCTGCTCAGTACCCAGCTCCTTCTGGCTCACTGGCATCCCA GGGCTGGAGTCCCTACACGTCTGGCTCTCCATCCCCTTTGGCTCCATGTACCTGGTGGCT GTGGTGGGGAATGTGACCATCCTGGCTGTGGTAAAGATAGAACGCAGCCTGCACCAGCCC ATGTACTTTTTCTTGTGCATGTTGGCTGCCATTGACCTGGTTCTGTCTACTTCCACTATA CCCAAACTTCTGGGAATCTTCTGGTTCGGTGCTTGTGACATTGGCCTGGACGCCTGCTTG GGCCAAATGTTCCTTATCCACTGCTTTGCCACTGTTGAGTCAGGCATCTTCCTTGCCATG GCTTTTGATCGCTACGTGGCCATCTGCAACCCACTACGTCATAGCATGGTGCTCACTTAT ACAGTGGTGGGTCGTTTGGGGCTTGTTTCTCTCCTCCGGGGTGTTCTCTACATTGGACCT CTGCCTCTGATGATCCGCCTGCGGCTGCCCCTTTATAAAACCCATGTTATCTCCCACTCC TACTGTGAGCACATGGCTGTAGTTGCCTTGACATGTGGCGACAGCAGGGTCAATAATGTC TATGGGCTGAGCATCGGCTTTCTGGTGTTGATCCTGGACTCAGTGGCTATTGCTGCATCC TATGTGATGATTTTCAGGGCCGTGATGGGGTTAGCCACTCCTGAGGCTAGGCTTAAAACC CTGGGGACATGCGCTTCTCACCTCTGTGCCATCCTGATCTTTTATGTTCCCATTGCTGTT TCTTCCCTGATTCACCGATTTGGTCAGTGTGTGCCTCCTCCAGTCCACACTCTGCTGGCC AACTTCTATCTCCTCATTCCTCCAATCCTCAATCCCATTGTCTATGCTGTTCGCACCAAG CAGATCCGAGAGAGCCTTCTCCAAATACCAAGGATAGAAATGAAGATTAGA |
| Conceptual translation |
MLTFHNVCSVPSSFWLTGIPGLESLHVWLSIPFGSMYLVAVVGNVTILAVVKIERSLHQP MYFFLCMLAAIDLVLSTSTIPKLLGIFWFGACDIGLDACLGQMFLIHCFATVESGIFLAM AFDRYVAICNPLRHSMVLTYTVVGRLGLVSLLRGVLYIGPLPLMIRLRLPLYKTHVISHS YCEHMAVVALTCGDSRVNNVYGLSIGFLVLILDSVAIAASYVMIFRAVMGLATPEARLKT LGTCASHLCAILIFYVPIAVSSLIHRFGQCVPPPVHTLLANFYLLIPPILNPIVYAVRTK QIRESLLQIPRIEMKIR Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 4,567,108 | 4,567,107 | Ins(1) | -/T | rs34601471 (DbSNP) | |
| 11 | 4,566,796 | 4,566,796 | NS | A/G | M/V | rs61751910 (DbSNP) |
| 11 | 4,567,175 | 4,567,175 | NS | A/T | Q/L | rs35020860 (DbSNP) |
| 11 | 4,567,335 | 4,567,335 | NS | C/G | S/R | rs2657167 (DbSNP) |
| 11 | 4,566,883 | 4,566,883 | NS | C/G | L/V | rs61747524 (DbSNP) |
| 11 | 4,566,446 | 4,566,446 | NS | C/T | S/L | rs7112010 (DbSNP) |
| 11 | 4,566,790 | 4,566,790 | NS | C/T | R/C | rs61751908 (DbSNP) |
| 11 | 4,566,513 | 4,566,513 | SYN | A/C | I/I | rs11032738 (DbSNP) |
| 11 | 4,567,140 | 4,567,140 | SYN | A/C | T/T | rs61734243 (DbSNP) |
| 11 | 4,566,939 | 4,566,939 | SYN | A/G | K/K | rs61747538 (DbSNP) |
| 11 | 4,567,086 | 4,567,086 | SYN | A/G | V/V | rs61735146 (DbSNP) |
| 11 | 4,566,711 | 4,566,711 | SYN | C/T | D/D | rs2709182 (DbSNP) |
| 11 | 4,566,718 | 4,566,718 | SYN | C/T | L/L | rs61747646 (DbSNP) |
| 11 | 4,566,870 | 4,566,870 | SYN | C/T | S/S | rs61747520 (DbSNP) |
| 11 | 4,567,185 | 4,567,185 | SYN | C/T | Y/Y | rs12295898 (DbSNP) |
| 11 | 4,567,152 | 4,567,152 | SYN | C/T | C/C | rs61734237 (DbSNP) |
| 11 | 4,545,481 | 4,545,481 | SYN | C/T | D/D | 1000GP (CEU, CHBJPT) |
| 11 | 4,546,105 | 4,546,105 | NS | C/G | S/R | 1000GP (CEU, CHBJPT) |
| 11 | 4,545,640 | 4,545,640 | SYN | T/C | S/S | 1000GP (CEU, CHBJPT) |
| 11 | 4,545,955 | 4,545,955 | SYN | T/C | Y/Y | 1000GP (CEU) |
| 11 | 100 | -100 | NS | C/A | P/H | 1000GP (YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | C/T | D/D | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 4,535,321 | 4,578,714 | CopyNumber | Variation_9173 (DGV) |
| 11 | 4,566,321 | 4,569,371 | CopyNumber | #118 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| S9L | P32H | P131S | I258T | R298H | S305R | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|
| 1 | S | P | P | I | R | S | 57.76 | 0.138 |
| 2 | S | P | P | I | R | R | 40.02 | 0.138 |
| 3 | L | P | P | I | H | R | 0.92 | 0.138 |
| 4 | S | P | S | I | R | R | 0.38 | 0.255 |
| 5 | S | H | P | I | R | R | 0.38 | 0.138 |
| 6 | S | P | P | T | R | S | 0.31 | 0.138 |
| 7 | L | P | P | I | R | R | 0.15 | 0.138 |
| 8 | S | P | P | I | H | R | 0.08 | 0.138 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR52M1.aApr07-unspliced | main_exon | CDS | chr11 | 4,545,191 | 4,546,141 | + |
| 3UTR | chr11 | 4,546,141 | 4,546,144 | + | ||