OR52N1 Olfactory Receptor
| Gene Symbol | OR52N11 (View this gene in GeneCards) |
| Family | 52 |
| Subfamily | N |
| Pseudogene | No |
| CORP pseudogene probability score | 0.31 (functional) |
| Aliases | OR11-61, HsOR11.3.81, ORL3381 |
| External Ids | HGNC: 14853 GeneBank: AB065538, BK004306, NM_001001913 ORDB: ORL3381 |
| Build #39 labels | OR52N1 |
| Chromosomal location | 11:5,787,857-5,788,816 (-) |
| Cluster | 11@6 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR52N2 | 76.11% | 314 |
| OR52N4 | 73.33% | 315 |
| OR52N5 | 71.95% | 303 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR52N4 | 74% | 320 |
| Mouse | Or52n1-ps | 87% | 317 |
| Rat | Or52n1 | 88% | 317 |
| Cow | OR52N2 | 76% | 310 |
| Orang | OR52N2P | 74% | 314 |
| Horse | OR52N4 | 74% | 320 |
| Chimp | OR52N2 | 77% | 314 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AK308796 |
Sequence information
| Nucleotide sequence |
ATGTCATTTCTAAATGGCACCAGCCTAACTCCAGCTTCATTCATCCTAAATGGCATCCCT GGTTTGGAAGATGTGCATTTGTGGATCTCCTTCCCACTGTGTACCATGTACAGCATTGCT ATTACAGGGAACTTCGGCCTTATGTACCTCATCTACTGTGATGAGGCCTTACACAGACCT ATGTATGTCTTCCTTGCCCTTCTTTCCTTCACAGATGTGCTCATGTGCACCAGCACCCTT CCCAACACTCTCTTCATATTGTGGTTTAATCTCAAGGAGATTGATTTTAAAGCCTGCCTC GCCCAGATGTTCTTTGTGCACACCTTCACAGGGATGGAGTCTGGGGTGCTCATGCTCATG GCCCTGGACCACTGTGTGGCCATCTGCTTCCCTCTGCGTTATGCCACCATCCTCACTAAT TCAGTCATTGCTAAAGCTGGGTTCCTCACTTTTCTTAGGGGTGTGATGCTTGTTATCCCT TCCACTTTCCTCACCAAGCGCCTTCCATACTGCAAGGGCAACGTCATACCCCACACCTAC TGTGACCACATGTCTGTGGCCAAGATATCTTGTGGTAATGTCAGGGTTAACGCCATCTAT GGTTTGATAGTTGCCCTGCTGATTGGGGGCTTTGATATCCTGTGCATTACAATCTCCTAC ACTATGATTCTTCAAGCAGTTGTGAGTCTATCATCAGCAGATGCTCGACAGAAGGCCTTC AGCACCTGCACTGCCCACTTCTGTGCCATAGTCCTCACCTATGTTCCAGCCTTCTTTACC TTCTTTACACACCATTTTGGGGGACACACCATTCCTCTACACATACATATTATTATGGCT AATCTCTACCTACTAATGCCTCCCACAATGAACCCTATTGTGTATGGGGTGAAAACCAGG CAGGTACGAGAAAGTGTCATTAGGTTCTTTCTTAAGGGAAAGGACAATTCTCATAACTTT |
| Conceptual translation |
MSFLNGTSLTPASFILNGIPGLEDVHLWISFPLCTMYSIAITGNFGLMYLIYCDEALHRP MYVFLALLSFTDVLMCTSTLPNTLFILWFNLKEIDFKACLAQMFFVHTFTGMESGVLMLM ALDHCVAICFPLRYATILTNSVIAKAGFLTFLRGVMLVIPSTFLTKRLPYCKGNVIPHTY CDHMSVAKISCGNVRVNAIYGLIVALLIGGFDILCITISYTMILQAVVSLSSADARQKAF STCTAHFCAIVLTYVPAFFTFFTHHFGGHTIPLHIHIIMANLYLLMPPTMNPIVYGVKTR QVRESVIRFFLKGKDNSHNF Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 5,809,248 | 5,809,248 | NS | A/C | W/G | rs11039036 (DbSNP) |
| 11 | 5,809,548 | 5,809,548 | NS | A/G | C/R | rs7948009 (DbSNP) |
| 11 | 5,809,308 | 5,809,308 | NS | A/T | F/I | rs7934670 (DbSNP) |
| 11 | 5,809,746 | 5,809,746 | NS | C/T | A/T | rs10742787 (DbSNP) |
| 11 | 5,809,673 | 5,809,673 | NS | C/T | C/Y | rs10769224 (DbSNP) |
| 11 | 5,809,811 | 5,809,811 | NS | G/T | T/N | rs12365487 (DbSNP) |
| 11 | 5,809,230 | 5,809,230 | SYN | A/G | L/L | rs12794769 (DbSNP) |
| 11 | 5,809,477 | 5,809,477 | SYN | A/G | S/S | rs10838637 (DbSNP) |
| 11 | 5,809,990 | 5,809,990 | SYN | A/G | I/I | rs11039038 (DbSNP) |
| 11 | 5,809,288 | 5,809,288 | SYN | C/G | T/T | rs35850861 (DbSNP) |
| 11 | 5,809,405 | 5,809,405 | SYN | C/T | L/L | rs11823184 (DbSNP) |
| 11 | 5,788,318 | 5,788,318 | NS | G/A | R/C | 1000GP (CEU, CHBJPT) |
| 11 | 5,788,078 | 5,788,078 | NS | A/T | F/I | 1000GP (CEU, CHBJPT) |
| 11 | 5,788,760 | 5,788,760 | SYN | G/A | I/I | 1000GP (CEU, CHBJPT) |
| 11 | 5,788,000 | 5,788,000 | SYN | G/A | L/L | 1000GP (CEU, CHBJPT) |
| 11 | 5,788,581 | 5,788,581 | NS | G/T | T/N | 1000GP (CEU, CHBJPT) |
| 11 | 5,788,247 | 5,788,247 | SYN | A/G | S/S | 1000GP (CEU, CHBJPT) |
| 11 | 5,788,516 | 5,788,516 | NS | C/T | A/T | 1000GP (CEU, CHBJPT) |
| 11 | 5,788,443 | 5,788,443 | NS | C/T | C/Y | 1000GP (CEU, CHBJPT) |
| 11 | 100 | -100 | NS | T/C | H/R | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | A/G | S/S | 1000GP (YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 5,782,093 | 5,812,233 | CopyNumber | Variation_0414 (DGV), Variation_34987 (DGV) |
| 11 | 5,776,623 | 5,842,356 | CopyNumber | Variation_2902 (DGV) |
| 11 | 5,730,377 | 5,970,717 | CopyNumber | Variation_3836 (DGV) |
| 11 | 5,784,484 | 5,809,387 | CopyNumber | Variation_6926 (DGV) |
| 11 | 5,783,884 | 5,810,228 | CopyNumber | Variation_23218 (DGV) |
| 11 | 5,505,764 | 6,194,475 | CopyNumber | Variation_34458 (DGV) |
| 11 | 5,783,630 | 5,809,284 | CopyNumber | Variation_37479 (DGV) |
| 11 | 5,788,080 | 5,809,139 | CopyNumber | Variation_38053 (DGV) |
| 11 | 5,784,575 | 5,809,283 | CopyNumber | Variation_41250 (DGV) |
| 11 | 5,784,556 | 5,809,291 | CopyNumber | Variation_43822 (DGV) |
| 11 | 5,784,695 | 5,809,362 | CopyNumber | Variation_58525 (DGV) |
| 11 | 5,784,859 | 5,809,285 | CopyNumber | Variation_65851 (DGV) |
| 11 | 5,782,017 | 5,809,657 | CopyNumber | Variation_75531 (DGV), Variation_85631 (DGV) |
| 11 | 5,791,622 | 5,809,657 | CopyNumber | Variation_75532 (DGV) |
| 11 | 5,783,842 | 5,809,435 | CopyNumber | Variation_101118 (DGV) |
| 11 | 5,809,387 | 5,810,189 | InDel | Variation_11053 (DGV) |
| Deletion | 247 (Hasin) | |||
| 11 | 5,807,087 | 5,810,146 | Deletion, CopyNumber | #312 (Waszak) |
| 11 | 5,784,438 | 5,809,353 | Del(-24708) | #12(modil) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| H269R | F247I | K172N | R167C | C125Y | V116L | T108I | A101T | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | H | I | K | C | C | V | T | A | 55.68 | 0.397 |
| 2 | H | I | K | R | Y | V | T | T | 28.96 | 0.502 |
| 3 | H | F | K | R | C | V | T | A | 7.14 | 0.397 |
| 4 | H | I | K | R | C | V | T | A | 4.92 | 0.397 |
| 5 | R | I | K | R | Y | V | I | T | 1.61 | 0.502 |
| 6 | H | I | N | R | C | V | T | A | 0.69 | 0.397 |
| 7 | R | I | K | R | Y | V | T | T | 0.46 | 0.502 |
| 8 | H | I | K | R | Y | V | T | A | 0.15 | 0.502 |
| 9 | H | I | K | R | Y | L | T | T | 0.15 | 0.502 |
| 10 | H | F | K | R | Y | V | T | T | 0.08 | 0.502 |
| 11 | H | I | K | C | Y | V | T | T | 0.08 | 0.502 |
| 12 | H | I | K | C | Y | V | T | A | 0.08 | 0.502 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR52N1.aApr07-unspliced | main_exon | 3UTR | chr11 | 5,787,854 | 5,787,857 | - |
| CDS | chr11 | 5,787,857 | 5,788,816 | - | ||