OR52N5 Olfactory Receptor
| Gene Symbol | OR52N51 (View this gene in GeneCards) |
| Family | 52 |
| Subfamily | N |
| Pseudogene | No |
| CORP pseudogene probability score | 0.07 (functional) |
| Aliases | OR11-62, HsOR11.3.80, ORL3436 |
| External Ids | HGNC: 15231 GeneBank: AB065535, BK004300, NM_001001922 ORDB: ORL3436 |
| Build #39 labels | OR52N5 |
| Chromosomal location | 11:5,777,663-5,778,634 (-) |
| Cluster | 11@6 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR52N1 | 71.95% | 303 |
| OR52N2 | 73.62% | 307 |
| OR52N4 | 70.16% | 305 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR52N1 | 74% | 309 |
| Mouse | Or52n5 | 89% | 307 |
| Rat | Or52n5 | 91% | 287 |
| Cow | OR52N5B | 86% | 310 |
| Orang | OR52N1 | 73% | 307 |
| Horse | OR52N4J | 71% | 308 |
| Chimp | OR52N2 | 75% | 307 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136981 |
| GNF Atlas2 | gnf1h10690_at |
Sequence information
| Nucleotide sequence |
ATGCCTCTATTTAATTCATTATGCTGGTTTCCAACAATTCATGTGACTCCTCCATCTTTT ATTCTTAATGGAATACCTGGTCTGGAAAGAGTACATGTATGGATCTCCCTCCCACTCTGC ACAATGTACATCATCTTCCTTGTGGGGAATCTTGGTCTTGTGTACCTCATTTATTATGAG GAGTCCTTACATCATCCGATGTATTTTTTTTTTGGCCATGCTCTCTCCCTCATTGACCTC CTTACCTGCACCACCACTCTACCCAATGCACTCTGCATCTTCTGGTTCAGTCTCAAAGAA ATTAACTTCAATGCTTGCTTGGCCCAGATGTTCTTTGTTCATGGGTTCACAGGTGTGGAG TCTGGGGTGCTCATGCTCATGGCTCTAGACCGCTATGTAGCCATTTGCTACCCTTTGCGT TATGCTACCACACTCACCAACCCTATCATTGCCAAGGCTGAGCTTGCCACCTTCCTGAGG GGTGTATTGCTGATGATTCCTTTCCCATTCTTGGTTAAGCGTTTGCCTTTCTGCCAAAGC AATATTATCTCCCATACGTACTGCGACCACATGTCTGTAGTAAAGCTATCTTGTGCCAGC ATCAAGGTCAATGTAATCTATGGTCTAATGGTTGCTCTCCTGATTGGAGTGTTTGACATT TGTTGTATATCTTTGTCTTACACTTTGATCCTCAAGGCAGCGATCAGCCTCTCTTCATCA GATGCTCGGCAGAAGGCTTTCAGCACCTGCACTGCCCATATATCTGCCATCATCATCACC TATGTTCCAGCATTCTTCACTTTCTTTGCCCACCGTTTTGGGGGACACACAATTCCCCCT TCTCTTCACATCATTGTGGCTAATCTTTATCTTCTTCTTCCCCCAACTCTAAACCCTATT GTTTATGGAGTAAAGACAAAACAGATACGCAAGAGTGTCATAAAGTTCTTCCAGGGTGAT AAGGGTGCAGGT |
| Conceptual translation |
MPLFNSLCWFPTIHVTPPSFILNGIPGLERVHVWISLPLCTMYIIFLVGNLGLVYLIYYE ESLHHPMYFFFGHALSLIDLLTCTTTLPNALCIFWFSLKEINFNACLAQMFFVHGFTGVE SGVLMLMALDRYVAICYPLRYATTLTNPIIAKAELATFLRGVLLMIPFPFLVKRLPFCQS NIISHTYCDHMSVVKLSCASIKVNVIYGLMVALLIGVFDICCISLSYTLILKAAISLSSS DARQKAFSTCTAHISAIIITYVPAFFTFFAHRFGGHTIPPSLHIIVANLYLLLPPTLNPI VYGVKTKQIRKSVIKFFQGDKGAG Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 5,799,468 | 5,799,468 | NS | C/T | V/I | rs12360738 (DbSNP) |
| 11 | 5,799,481 | 5,799,481 | SYN | A/G | A/A | rs17230251 (DbSNP) |
| 11 | 5,778,238 | 5,778,238 | NS | C/T | V/I | 1000GP (CEU, CHBJPT) |
| 11 | 5,777,908 | 5,777,908 | NS | G/A | R/W | 1000GP (CHBJPT) |
| 11 | 5,777,937 | 5,777,937 | NS | G/C | A/G | 1000GP (CHBJPT) |
| 11 | 100 | -100 | NS | C/T | G/R | 1000GP (YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 5,782,093 | 5,812,233 | CopyNumber | Variation_0414 (DGV), Variation_34987 (DGV) |
| 11 | 5,776,623 | 5,842,356 | CopyNumber | Variation_2902 (DGV) |
| 11 | 5,730,377 | 5,970,717 | CopyNumber | Variation_3836 (DGV) |
| 11 | 5,784,484 | 5,809,387 | CopyNumber | Variation_6926 (DGV) |
| 11 | 5,783,884 | 5,810,228 | CopyNumber | Variation_23218 (DGV) |
| 11 | 5,784,904 | 5,809,056 | CopyNumber | Variation_30540 (DGV) |
| 11 | 5,799,860 | 5,807,979 | CopyNumber | Variation_31804 (DGV) |
| 11 | 5,505,764 | 6,194,475 | CopyNumber | Variation_34458 (DGV) |
| 11 | 5,783,630 | 5,809,284 | CopyNumber | Variation_37479 (DGV) |
| 11 | 5,788,080 | 5,809,139 | CopyNumber | Variation_38053 (DGV) |
| 11 | 5,784,575 | 5,809,283 | CopyNumber | Variation_41250 (DGV) |
| 11 | 5,784,556 | 5,809,291 | CopyNumber | Variation_43822 (DGV) |
| 11 | 5,777,210 | 5,805,515 | CopyNumber | Variation_48854 (DGV) |
| 11 | 5,784,695 | 5,809,362 | CopyNumber | Variation_58525 (DGV) |
| 11 | 5,784,859 | 5,809,285 | CopyNumber | Variation_65851 (DGV) |
| 11 | 5,782,017 | 5,809,657 | CopyNumber | Variation_75531 (DGV), Variation_85631 (DGV) |
| 11 | 5,791,622 | 5,809,657 | CopyNumber | Variation_75532 (DGV) |
| 11 | 5,783,842 | 5,809,435 | CopyNumber | Variation_101118 (DGV) |
| Deletion | 246 (Hasin) | |||
| 11 | 5,796,893 | 5,799,964 | Deletion | #17 (Waszak) |
| 11 | 5,784,438 | 5,809,353 | Del(-24708) | #13(modil) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| R243W | I223T | V133I | G122R | G118D | % Freq | CORP | |
|---|---|---|---|---|---|---|---|
| 1 | R | I | V | G | G | 81.41 | 0.083 |
| 2 | R | I | I | G | G | 16.28 | 0.083 |
| 3 | R | I | V | G | D | 0.84 | 0.083 |
| 4 | R | I | V | R | G | 0.61 | 0.083 |
| 5 | R | T | V | G | G | 0.38 | 0.083 |
| 6 | W | I | V | G | G | 0.31 | 0.069 |
| 7 | W | I | I | G | G | 0.08 | 0.069 |
| 8 | R | I | I | R | G | 0.08 | 0.083 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR52N5.aApr07-unspliced | main_exon | 3UTR | chr11 | 5,777,660 | 5,777,663 | - |
| CDS | chr11 | 5,777,663 | 5,778,634 | - | ||