OR52W1 Olfactory Receptor
| Gene Symbol | OR52W11 (View this gene in GeneCards) |
| Family | 52 |
| Subfamily | W |
| Pseudogene | No |
| CORP pseudogene probability score | 0.13 (functional) |
| Aliases | OR11-71, HsOR11.3.102 |
| External Ids | HGNC: 15239 GeneBank: AB065511, BK004399, NM_001005178 |
| Build #39 labels | OR52W1P |
| Chromosomal location | 11:6,199,224-6,200,183 (+) |
| Cluster | 11@6 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR52D1 | 46.91% | 307 |
| OR52L1 | 51.34% | 298 |
| OR52L2P | 49.83% | 303 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR52R1 | 49% | 299 |
| Mouse | Or52w1 | 80% | 318 |
| Rat | Or52w1 | 79% | 318 |
| Cow | OR52R1E | 48% | 308 |
| Orang | OR52W1P | 96% | 320 |
| Horse | OR52R1H | 49% | 304 |
| Chimp | OR52L1 | 50% | 305 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC137225 |
Sequence information
| Nucleotide sequence |
ATGGCAGAAACTCTACAACTCAATTCCACCTTCCTACACCCAAACTTCTTCATACTGACT GGCTTTCCAGGGCTAGGAAGTGCCCAGACTTGGCTGACACTGGTCTTTGGGCCCATTTAT CTGCTGGCCCTGCTGGGCAATGGAGCACTGCCGGCAGTGGTGTGGATAGACTCCACACTG CACCAGCCCATGTTTCTACTGTTGGCCATCCTGGCAGCCACAGACCTGGGCTTAGCCACA TCTATAGCCCCAGGGTTGCTGGCTGTGCTGTGGCTTGGGCCCCGATCTGTGCCATATGCT GTGTGCCTGGTCCAGATGTTCTTTGTACATGCACTGACTGCCATGGAATCAGGTGTGCTT TTGGCCATGGCCTGTGATCGTGCTGCGGCAATAGGGCGTCCACTGCACTACCCTGTCCTG GTCACCAAAGCCTGTGTGGGTTATGCAGCCTTGGCCCTGGCACTGAAAGCTGTGGCTATT GTTGTACCTTTCCCACTGCTGGTGGCAAAGTTTGAGCACTTCCAAGCCAAGACCATAGGC CATACCTATTGTGCACACATGGCAGTGGTAGAACTGGTGGTGGGTAACACACAGGCCACC AACTTATATGGTCTGGCACTTTCACTGGCCATCTCAGGTATGGATATTCTGGGTATCACT GGCTCCTATGGACTCATTGCCCATGCTGTGCTGCAGCTACCTACCCGGGAGGCCCATGCC AAGGCCTTTGGTACATGTAGTTCTCACATCTGTGTCATTCTGGCCTTCTACATACCTGGT CTCTTCTCCTACCTCACACACCGCTTTGGTCATCACACTGTCCCAAAGCCTGTGCACATC CTTCTCTCCAACATCTACTTGCTGCTGCCACCTGCCCTCAACCCCCTCATCTATGGGGCC CGCACCAAGCAGATCAGAGACCGACTCCTGGAAACCTTCACATTCAGAAAAAGCCCGTTG |
| Conceptual translation |
MAETLQLNSTFLHPNFFILTGFPGLGSAQTWLTLVFGPIYLLALLGNGALPAVVWIDSTL HQPMFLLLAILAATDLGLATSIAPGLLAVLWLGPRSVPYAVCLVQMFFVHALTAMESGVL LAMACDRAAAIGRPLHYPVLVTKACVGYAALALALKAVAIVVPFPLLVAKFEHFQAKTIG HTYCAHMAVVELVVGNTQATNLYGLALSLAISGMDILGITGSYGLIAHAVLQLPTREAHA KAFGTCSSHICVILAFYIPGLFSYLTHRFGHHTVPKPVHILLSNIYLLLPPALNPLIYGA RTKQIRDRLLETFTFRKSPL Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 6,220,870 | 6,220,869 | Ins(1) | -/T | rs34411693 (DbSNP) | |
| 11 | 6,221,169 | 6,221,169 | NS | A/G | H/R | rs10839531 (DbSNP) |
| 11 | 6,221,249 | 6,221,249 | NS | A/G | T/A | rs325609 (DbSNP) |
| 11 | 6,221,214 | 6,221,214 | NS | A/T | Q/L | rs11040799 (DbSNP) |
| 11 | 6,221,196 | 6,221,196 | NS | C/T | S/F | rs73392966 (DbSNP) |
| 11 | 6,221,179 | 6,221,179 | SYN | C/T | A/A | rs74053127 (DbSNP) |
| 11 | 6,200,019 | 6,200,019 | NS | A/G | T/A | 1000GP (CEU) |
| 11 | 6,199,984 | 6,199,984 | NS | T/A | L/Q | 1000GP (CEU, CHBJPT) |
| 11 | 6,199,939 | 6,199,939 | NS | A/G | H/R | 1000GP (CEU, CHBJPT) |
| 11 | 6,199,707 | 6,199,707 | NS | G/T | V/L | 1000GP (CHBJPT) |
| 11 | 100 | -100 | NS | T/C | L/P | 1000GP (YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | C/T | A/A | 1000GP (YRI, YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| P51L | L87P | H239R | L254Q | T266A | R308Q | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|
| 1 | P | L | R | Q | T | R | 60.06 | 0.098 |
| 2 | P | L | H | L | T | R | 23.66 | 0.082 |
| 3 | P | L | R | L | T | R | 8.53 | 0.098 |
| 4 | P | L | H | L | A | R | 6.22 | 0.082 |
| 5 | P | P | R | L | T | R | 0.61 | 0.076 |
| 6 | L | L | H | L | T | R | 0.38 | 0.082 |
| 7 | P | L | R | L | T | Q | 0.23 | 0.098 |
| 8 | P | L | R | Q | T | Q | 0.23 | 0.098 |
| 9 | P | L | H | Q | T | R | 0.08 | 0.082 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR52W1.aApr07-unspliced | main_exon | CDS | chr11 | 6,199,224 | 6,200,183 | + |
| 3UTR | chr11 | 6,200,183 | 6,200,186 | + | ||