OR56A5 Olfactory Receptor
| Gene Symbol | OR56A51 (View this gene in GeneCards) |
| Family | 56 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 0.49 (functional) |
| Aliases | HsOR11.3.91 |
| External Ids | HGNC: 14792 GeneBank: NG_002219, XM_372371 |
| Build #39 labels | OR56A5P |
| Chromosomal location | 11:5,967,556-5,968,494 (-) |
| Cluster | 11@6 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR56A4 | 87.22% | 313 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR56A4C | 89% | 313 |
| Mouse | Or56a5 | 85% | 312 |
| Mouse | Or56a4 | 83% | 309 |
| Rat | Or56a5 | 85% | 312 |
| Cow | OR56A4D | 87% | 313 |
| Cow | OR56A4P | 86% | 309 |
| Cow | OR56A4E | 84% | 313 |
| Orang | OR56A4 | 88% | 313 |
| Horse | OR56A4 | 85% | 313 |
| Chimp | OR56A4 | 87% | 313 |
Expression evidences
| Source | Accession |
|---|---|
| GNF Atlas2 | gnf1h05431_at |
| GNF Atlas2 | gnf1h05432_x_at |
| GNF Atlas2 | gnf1h11014_at |
Sequence information
| Nucleotide sequence |
ATGACATTACCCAGCAACAACTCCACTTCCCCAGTCTTTGAATTCTTCCTCATTTGTTTC CCCAGTTTCCAGAGCTGGCAGCACTGGCTGTCTCTGCCCCTCAGCCTCCTCTTCCTCCTG GCCATGGGGGCCAATGCCACCCTTCTGATCACCATCTATCTGGAAGCCTCTCTGCACCAG CCCCTGTACTACCTGCTCAGCCTCCTCTCCCTGCTGGACATCGTACTCTGCCTCACCGTC ATCCCCAAGGTCCTGGCCATCTTCTGGTTTGACCTCAGATCAATCAGCTTCCCTGCCTGC TTCCTTCAGGTGTTCATCATGAACAGTTTTCTGACTATGGAGTCCTGCACATTCATGATC ATGGCCTATGACCGCTATGTGGCCATCTGCAAGCCCCTACAGTACTCATCCATCATCACT GATCAATTTGTCGCTAGGGCTGCCATCTTTGTTGTGGCCAGGAATGGCCTTCTTACTATG CCTATCCCCATACTTTCTTCTCGACTCAGATACTGTGCAGGACACATCATCAAGAACTGC ATCTGTACTAACGTGTCTGTGTCTAAACTCTCTTGTGATGACATCACCTTGAATCAGAGC TACCAGTTTGTTATAGGTTGGACCCTGCTGGGCTCTGACCTCATCCTTATTGTTCTCTCT TACTTTTTTATCTTGAAAACTGTGCTAAGGATTAAGGGTGAGGGAGATATGGCCAAAGCT CTAGGTACTTGTGGTTCCCACTTCATCCTCATCCTCTTCTTCACCACAGTCCTGCTGGTT CTGGTCATCACTAACCTGGCCAGGAAGAGAATTCCTCCGGATGTCCCCATCCTGCTCAAC ATCCTGCACCACCTTATTCCCCCAGCTCTGAACCCCATTGTTTATGGTGTGAGAACCAAG GAGATCAAGCAGGGAATCCAGAACCTGCTGAGGAGGTTG |
| Conceptual translation |
MTLPSNNSTSPVFEFFLICFPSFQSWQHWLSLPLSLLFLLAMGANATLLITIYLEASLHQ PLYYLLSLLSLLDIVLCLTVIPKVLAIFWFDLRSISFPACFLQVFIMNSFLTMESCTFMI MAYDRYVAICKPLQYSSIITDQFVARAAIFVVARNGLLTMPIPILSSRLRYCAGHIIKNC ICTNVSVSKLSCDDITLNQSYQFVIGWTLLGSDLILIVLSYFFILKTVLRIKGEGDMAKA LGTCGSHFILILFFTTVLLVLVITNLARKRIPPDVPILLNILHHLIPPALNPIVYGVRTK EIKQGIQNLLRRL Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 5,989,223 | 5,989,223 | nonsense SNP | A/G | */R | rs61730422 (DbSNP) |
| 11 | 5,989,415 | 5,989,415 | NS | A/C/T | L/V | rs7114672 (DbSNP) |
| 11 | 5,988,907 | 5,988,907 | NS | A/G | L/P | rs7113015 (DbSNP) |
| 11 | 5,989,191 | 5,989,191 | NS | C/G | K/N | rs61737576 (DbSNP) |
| 11 | 5,989,293 | 5,989,293 | SYN | A/G | V/V | rs7113548 (DbSNP) |
| 11 | 5,989,686 | 5,989,686 | SYN | A/G | F/F | rs74053258 (DbSNP) |
| 11 | 5,967,993 | 5,967,993 | nonsense SNP | G/A | R/* | 1000GP (CEU) |
| 11 | 5,968,185 | 5,968,185 | NS | C/T | V/M | 1000GP (CEU, CHBJPT) |
| 11 | 5,968,052 | 5,968,052 | NS | G/A | A/V | 1000GP (CEU) |
| 11 | 5,968,063 | 5,968,063 | SYN | G/A | V/V | 1000GP (CEU, CHBJPT) |
| 11 | 100 | -100 | SYN | C/T | P/P | 1000GP (YRI, YRI) |
| 11 | 100 | -100 | NS | G/A | P/L | 1000GP (YRI, YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 5,868,055 | 6,007,613 | CopyNumber | Variation_2903 (DGV) |
| 11 | 5,505,764 | 6,194,475 | CopyNumber | Variation_34458 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| P205L | L191P | N116I | K110N | R100* | A80V | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|
| 1 | P | L | N | K | R | A | 93.55 | 0.989 |
| 2 | P | L | N | K | * | A | 3.46 | 1.200 |
| 3 | P | L | N | K | R | V | 1.46 | 0.989 |
| 4 | P | L | N | N | R | A | 0.69 | 0.989 |
| 5 | L | L | N | K | R | A | 0.31 | 0.989 |
| 6 | P | P | N | K | R | A | 0.31 | 0.989 |
| 7 | P | L | I | K | R | A | 0.23 | 0.989 |