OR56B1 Olfactory Receptor
| Gene Symbol | OR56B11 (View this gene in GeneCards) |
| Family | 56 |
| Subfamily | B |
| Pseudogene | No |
| CORP pseudogene probability score | 0 (functional) |
| Aliases | OR11-65, HsOR11.3.77 |
| External Ids | HGNC: 15245 GeneBank: AB065812, BK004386, NM_001005180 |
| Build #39 labels | OR56B1P |
| Chromosomal location | 11:5,736,526-5,737,488 (+) |
| Cluster | 11@6 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR56B2P | 73.29% | 292 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR56B2C | 75% | 312 |
| Mouse | Or56b1 | 86% | 311 |
| Rat | Or56b1 | 83% | 312 |
| Cow | OR56B44P | 73% | 309 |
| Orang | OR56B1P | 93% | 321 |
| Horse | OR56B2 | 74% | 312 |
| Chimp | OR56B2 | 73% | 292 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | DB108991 |
| mRNA | BC137185 |
Sequence information
| Nucleotide sequence |
ATGTCTGCATCTCTCAAAATCTCCAATAGCTCCAAATTCCAGGTCTCTGAGTTCATCCTG CTGGGATTCCCGGGCATTCACAGCTGGCAACACTGGCTATCTCTGCCCCTGGCACTACTG TATCTCTCAGCACTTGCTGCAAACACCCTCATCCTCATCATCATCTGGCAGAACCCTTCT TTACAGCAGCCCATGTATATTTTCCTTGGCATCCTCTGTATGGTAGACATGGGTCTGGCC ACTACTATCATCCCTAAGATCCTGGCCATCTTCTGGTTTGATGCCAAGGTTATTAGCCTC CCTGAGTGCTTTGCTCAGATTTATGCCATTCACTTCTTTGTGGGCATGGAGTCTGGTATC CTACTCTGCATGGCTTTTGATAGATATGTGGCTATTTGTCACCCTCTTCGCTATCCATCA ATTGTCACCAGTTCCTTAATCTTAAAAGCTACCCTGTTCATGGTGCTGAGAAATGGCTTA TTTGTCACTCCAGTGCCTGTGCTTGCAGCACAGCGTGATTATTGCTCCAAGAATGAAATT GAACACTGCCTGTGCTCTAACCTTGGGGTCACAAGCCTGGCTTGTGATGACAGGAGGCCA AACAGCATTTGCCAGTTGGTTCTGGCATGGCTTGGAATGGGGAGTGATCTAAGTCTTATT ATACTGTCATATATTTTGATTCTGTACTCTGTACTTAGACTGAACTCAGCTGAAGCTGCA GCCAAGGCCCTGAGCACTTGTAGTTCACATCTCACCCTCATCCTTTTCTTTTACACTATT GTTGTAGTGATTTCAGTGACTCATCTGACAGAGATGAAGGCTACTTTGATTCCAGTTCTA CTTAATGTGTTGCACAACATCATCCCCCCTTCCCTCAACCCTACAGTTTATGCACTTCAG ACCAAAGAACTTAGGGCAGCCTTCCAAAAGGTGCTGTTTGCCCTTACAAAAGAAATAAGA TCT |
| Conceptual translation |
MSASLKISNSSKFQVSEFILLGFPGIHSWQHWLSLPLALLYLSALAANTLILIIIWQNPS LQQPMYIFLGILCMVDMGLATTIIPKILAIFWFDAKVISLPECFAQIYAIHFFVGMESGI LLCMAFDRYVAICHPLRYPSIVTSSLILKATLFMVLRNGLFVTPVPVLAAQRDYCSKNEI EHCLCSNLGVTSLACDDRRPNSICQLVLAWLGMGSDLSLIILSYILILYSVLRLNSAEAA AKALSTCSSHLTLILFFYTIVVVISVTHLTEMKATLIPVLLNVLHNIIPPSLNPTVYALQ TKELRAAFQKVLFALTKEIRS Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 5,758,398 | 5,758,397 | Ins(1) | -/G | rs36073866 (DbSNP) | |
| 11 | 5,758,002 | 5,758,002 | NS | A/G | I/V | rs74051091 (DbSNP) |
| 11 | 5,758,270 | 5,758,270 | NS | A/G | H/R | rs62617826 (DbSNP) |
| 11 | 5,758,062 | 5,758,062 | NS | C/T | R/C | rs7397032 (DbSNP) |
| 11 | 5,758,386 | 5,758,386 | NS | C/T | L/F | rs62621167 (DbSNP) |
| 11 | 5,758,447 | 5,758,447 | NS | G/T | G/V | rs35783800 (DbSNP) |
| 11 | 5,758,118 | 5,758,118 | SYN | A/C | L/L | rs7396766 (DbSNP) |
| 11 | 5,758,646 | 5,758,646 | SYN | C/T | Y/Y | rs4486660 (DbSNP) |
| 11 | 5,757,785 | 5,757,785 | SYN | C/T | S/S | rs12792180 (DbSNP) |
| 11 | 5,736,888 | 5,736,888 | SYN | A/C | L/L | 1000GP (CEU, CHBJPT) |
| 11 | 5,736,832 | 5,736,832 | NS | T/C | C/R | 1000GP (CEU, CHBJPT) |
| 11 | 5,736,555 | 5,736,555 | SYN | C/T | S/S | 1000GP (CEU, CHBJPT) |
| 11 | 5,737,416 | 5,737,416 | SYN | T/C | Y/Y | 1000GP (CEU, CHBJPT) |
| 11 | 5,736,821 | 5,736,821 | NS | G/A | S/N | 1000GP (CHBJPT) |
| 11 | 5,736,923 | 5,736,923 | NS | G/T | C/F | 1000GP (CHBJPT) |
| 11 | 100 | -100 | SYN | C/T | S/S | 1000GP (YRI, YRI) |
| 11 | 100 | -100 | NS | A/G | I/V | 1000GP (YRI, YRI, YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 5,730,377 | 5,970,717 | CopyNumber | Variation_3836 (DGV) |
| 11 | 5,505,764 | 6,194,475 | CopyNumber | Variation_34458 (DGV) |
| 11 | 5,757,656 | 5,760,718 | Deletion | #200 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| I86V | K89R | S102N | C106R | N161H | R175H | L214F | S221N | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | I | K | S | R | N | R | L | S | 71.66 | 0.026 |
| 2 | I | K | S | C | N | R | L | S | 20.12 | 0.026 |
| 3 | I | K | S | C | N | H | L | S | 3.76 | 0.026 |
| 4 | I | K | S | R | N | R | F | S | 2.15 | 0.026 |
| 5 | I | K | N | C | N | R | L | S | 0.92 | 0.026 |
| 6 | V | K | S | R | N | R | L | S | 0.61 | 0.026 |
| 7 | I | K | S | C | N | R | L | N | 0.38 | 0.026 |
| 8 | I | K | S | R | H | R | L | S | 0.23 | 0.026 |
| 9 | I | R | S | C | N | R | L | S | 0.08 | 0.026 |
| 10 | I | R | S | R | N | R | L | S | 0.08 | 0.026 |