OR56B4 Olfactory Receptor
| Gene Symbol | OR56B41 (View this gene in GeneCards) |
| Family | 56 |
| Subfamily | B |
| Pseudogene | No |
| CORP pseudogene probability score | 0.03 (functional) |
| Aliases | OR11-67, HsOR11.3.98, ORL3420 |
| External Ids | HGNC: 15248 GeneBank: AB065513, BK004325, NM_001005181 ORDB: ORL3420 |
| Build #39 labels | OR56B4 |
| Chromosomal location | 11:6,107,779-6,108,735 (+) |
| Cluster | 11@6 |
| Synteny | CLIC#23 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR56B3P | 75.31% | 320 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR56B6 | 73% | 320 |
| Mouse | Or56b34 | 71% | 320 |
| Rat | Or56b6b | 69% | 320 |
| Cow | OR56B42 | 66% | 325 |
| Orang | OR56B3P | 77% | 311 |
| Horse | OR56B46 | 75% | 320 |
| Chimp | OR56B3P | 76% | 305 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136880 |
Sequence information
| Nucleotide sequence |
ATGGATACCTCCACCAGTGTTACCTATGACTCCAGCCTCCAGATTTCCCAGTTCATCCTG ATGGGATTACCAGGCATTCATGAGTGGCAGCACTGGCTCTCCCTGCCCCTGACTCTGCTC TACCTCTTAGCTCTTGGTGCCAATCTCCTCATCATAATCACCATTCAACATGAGACCGTG CTACATGAACCCATGTACCATTTGCTGGGCATATTAGCAGTGGTGGACATTGGCCTGGCC ACCACCATCATGCCCAAGATCCTGGCCATCTTCTGGTTTGATGCCAAGGCCATTAGCCTC CCCATGTGTTTTGCTCAGATCTATGCCATCCACTGCTTCTTCTGCATAGAGTCAGGCATC TTTCTCTGCATGGCAGTAGACAGATACATAGCCATCTGTCGCCCTCTTCAGTACCCCTCC ATAGTCACTAAAGCTTTTGTCTTCAAAGCCACAGGGTTCATCATGCTCAGGAATGGCCTG TTGACCATCCCAGTGCCTATACTGGCTGCCCAGAGACACTACTGTTCCAGGAATGAAATC GAGCACTGCCTCTGCTCTAACTTGGGGGTTATCAGCCTGGCTTGTGATGACATCACTGTG AACAAATTTTACCAACTGATGCTAGCATGGGTCTTGGTTGGGAGTGATATGGCTCTGGTA TTTTCTTCCTATGCTGTAATCCTTCACTCTGTGCTGAGGCTGAACTCAGCAGAAGCAATG TCCAAGGCTCTGAGCACTTGTAGCTCCCACCTCATCCTCATCCTCTTCCACACAGGTATC ATTGTGCTGTCTGTCACACACCTTGCAGAGAAAAAGATTCCCCTTATTCCTGTGTTCCTT AATGTGCTGCACAATGTCATCCCCCCTGCACTCAACCCCCTGGCCTGTGCACTCAGGATG CACAAACTCAGACTGGGCTTTCAGAGACTGCTTGGACTGGGTCAGGACGTGTCCAAG |
| Conceptual translation |
MDTSTSVTYDSSLQISQFILMGLPGIHEWQHWLSLPLTLLYLLALGANLLIIITIQHETV LHEPMYHLLGILAVVDIGLATTIMPKILAIFWFDAKAISLPMCFAQIYAIHCFFCIESGI FLCMAVDRYIAICRPLQYPSIVTKAFVFKATGFIMLRNGLLTIPVPILAAQRHYCSRNEI EHCLCSNLGVISLACDDITVNKFYQLMLAWVLVGSDMALVFSSYAVILHSVLRLNSAEAM SKALSTCSSHLILILFHTGIIVLSVTHLAEKKIPLIPVFLNVLHNVIPPALNPLACALRM HKLRLGFQRLLGLGQDVSK Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 6,129,409 | 6,129,409 | NS | A/G | H/R | rs61743916 (DbSNP) |
| 11 | 6,129,334 | 6,129,334 | NS | C/T | A/V | rs61745227 (DbSNP) |
| 11 | 6,129,837 | 6,129,837 | NS | C/T | P/S | rs1462983 (DbSNP) |
| 11 | 6,129,756 | 6,129,756 | NS | C/T | H/Y | rs58431577 (DbSNP) |
| 11 | 6,129,923 | 6,129,923 | SYN | A/G | L/L | rs74055136 (DbSNP) |
| 11 | 6,129,152 | 6,129,152 | SYN | C/T | N/N | rs4758387 (DbSNP) |
| 11 | 6,107,922 | 6,107,922 | SYN | T/C | N/N | 1000GP (CEU) |
| 11 | 6,108,607 | 6,108,607 | NS | C/T | P/S | 1000GP (CEU, CHBJPT) |
| 11 | 6,108,526 | 6,108,526 | NS | C/T | H/Y | 1000GP (CHBJPT) |
| 11 | 100 | -100 | NS | C/T | P/S | 1000GP (YRI) |
| 11 | 100 | -100 | SYN | G/A | L/L | 1000GP (YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 5,505,764 | 6,194,475 | CopyNumber | Variation_34458 (DGV) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| H57Y | H250Y | P277S | % Freq | CORP | |
|---|---|---|---|---|---|
| 1 | H | H | P | 53.84 | 0.046 |
| 2 | H | H | S | 45.78 | 0.046 |
| 3 | H | Y | S | 0.31 | 0.397 |
| 4 | Y | H | P | 0.08 | 0.046 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR56B4.aApr07-unspliced | main_exon | CDS | chr11 | 6,107,779 | 6,108,735 | + |
| 3UTR | chr11 | 6,108,735 | 6,108,738 | + | ||