OR5A1 Olfactory Receptor
| Gene Symbol | OR5A11 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | A |
| Pseudogene | No |
| CORP pseudogene probability score | 0.1 (functional) |
| Aliases | OST181, OR11-249, HsOR11.13.6, ORL3301 |
| External Ids | HGNC: 8319 GeneBank: AB065804, AF399528, BK004310, NM_001004728 ORDB: ORL3301 |
| Build #39 labels | OR5A1 |
| Chromosomal location | 11:59,443,169-59,444,113 (+) |
| Cluster | 11@59a |
| Synteny | CLIC#27 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5A2 | 67.33% | 303 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5A2 | 67% | 314 |
| Mouse | Or5a1 | 84% | 314 |
| Rat | Or5a1 | 82% | 315 |
| Cow | OR5AN2 | 61% | 310 |
| Orang | OR5A1P | 91% | 302 |
| Horse | OR5A1C | 86% | 315 |
| Horse | OR5A1B | 86% | 314 |
| Chimp | OR5A2 | 67% | 303 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC137061 |
| GNF Atlas2 | gnf1h02106_at |
Sequence information
| Nucleotide sequence |
ATGTCCATAACCAAAGCCTGGAACAGCTCATCAGTGACCATGTTCATCCTCCTGGGATTC ACAGACCATCCAGAACTCCAGGCCCTCCTCTTTGTGACCTTCCTGGGCATCTATCTTACC ACCCTGGCCTGGAACCTGGCCCTCATTTTTCTGATCAGAGGTGACACCCATCTGCACACA CCCATGTACTTCTTCCTAAGCAACTTATCTTTCATTGACATCTGCTACTCTTCTGCTGTG GCTCCCAATATGCTCACTGACTTCTTCTGGGAGCAGAAGACCATATCATTTGTGGGCTGT GCTGCTCAGTTTTTTTTCTTTGTCGGCATGGGTCTGTCTGAGTGCCTCCTCCTGACTGCT ATGGCATACGACCGATATGCAGCCATCTCCAGCCCCCTTCTCTACCCCACTATCATGACC CAGGGCCTCTGTACACGCATGGTGGTTGGGGCATATGTTGGTGGCTTCCTGAGCTCCCTG ATCCAGGCCAGCTCCATATTTAGGCTTCACTTTTGCGGACCCAACATCATCAACCACTTC TTCTGCGACCTCCCACCAGTCCTGGCTCTGTCTTGCTCTGACACCTTCCTCAGTCAAGTG GTGAATTTCCTCGTGGTGGTCACTGTCGGAGGAACATCGTTCCTCCAACTCCTTATCTCC TATGGTTACATAGTGTCTGCGGTCCTGAAGATCCCTTCAGCAGAGGGCCGATGGAAAGCC TGCAACACGTGTGCCTCGCATCTGATGGTGGTGACTCTGCTGTTTGGGACAGCCCTTTTC GTGTACTTGCGACCCAGCTCCAGCTACTTGCTAGGCAGGGACAAGGTGGTGTCTGTTTTC TATTCATTGGTGATCCCCATGCTGAACCCTCTCATTTACAGTTTGAGGAACAAAGAGATC AAGGATGCCCTGTGGAAGGTGTTGGAAAGGAAGAAAGTGTTTTCT |
| Conceptual translation |
MSITKAWNSSSVTMFILLGFTDHPELQALLFVTFLGIYLTTLAWNLALIFLIRGDTHLHT PMYFFLSNLSFIDICYSSAVAPNMLTDFFWEQKTISFVGCAAQFFFFVGMGLSECLLLTA MAYDRYAAISSPLLYPTIMTQGLCTRMVVGAYVGGFLSSLIQASSIFRLHFCGPNIINHF FCDLPPVLALSCSDTFLSQVVNFLVVVTVGGTSFLQLLISYGYIVSAVLKIPSAEGRWKA CNTCASHLMVVTLLFGTALFVYLRPSSSYLLGRDKVVSVFYSLVIPMLNPLIYSLRNKEI KDALWKVLERKKVFS Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 59,211,188 | 59,211,188 | NS | A/G | N/D | rs6591536 (DbSNP) |
| 11 | 59,210,795 | 59,210,795 | NS | A/G | I/V | rs17153732 (DbSNP) |
| 11 | 59,210,761 | 59,210,761 | SYN | C/G | T/T | rs11605572 (DbSNP) |
| 11 | 59,211,325 | 59,211,325 | SYN | C/T | V/V | rs72923336 (DbSNP) |
| 11 | 59,211,421 | 59,211,421 | SYN | C/T | F/F | rs17591107 (DbSNP) |
| 11 | 59,211,265 | 59,211,265 | SYN | C/T | T/T | rs7941591 (DbSNP) |
| 11 | 59,443,948 | 59,443,948 | SYN | C/T | F/F | 1000GP (CEU, CHBJPT) |
| 11 | 59,443,715 | 59,443,715 | NS | G/A | D/N | 1000GP (CEU, CHBJPT) |
| 11 | 59,444,085 | 59,444,085 | NS | A/C | K/T | 1000GP (CEU) |
| 11 | 59,443,288 | 59,443,288 | SYN | C/G | T/T | 1000GP (CEU, CHBJPT) |
| 11 | 59,443,792 | 59,443,792 | SYN | T/C | T/T | 1000GP (CEU, CHBJPT) |
| 11 | 59,443,852 | 59,443,852 | SYN | C/T | V/V | 1000GP (CEU) |
| 11 | 59,443,322 | 59,443,322 | NS | A/G | I/V | 1000GP (CHBJPT) |
| 11 | 100 | -100 | SYN | C/T | L/L | 1000GP (YRI, YRI, YRI) |
| 11 | 100 | -100 | NS | G/A | D/N | 1000GP (YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 59,210,542 | 59,213,586 | CopyNumber | #78 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| I52V | R146H | D183N | % Freq | CORP | |
|---|---|---|---|---|---|
| 1 | I | R | N | 61.52 | 0.251 |
| 2 | I | R | D | 35.56 | 0.251 |
| 3 | V | R | D | 2.76 | 0.251 |
| 4 | I | H | N | 0.15 | 0.251 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5A1.aApr07-unspliced | main_exon | CDS | chr11 | 59,443,169 | 59,444,113 | + |
| 3UTR | chr11 | 59,444,113 | 59,444,116 | + | ||