OR5AC2 Olfactory Receptor
| Gene Symbol | OR5AC21 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | AC |
| Pseudogene | No |
| CORP pseudogene probability score | 0.07 (functional) |
| Aliases | HSA1, HsOR3.3.2, ORL3810 |
| External Ids | HGNC: 15431 GeneBank: AF179759, NM_054106 ORDB: ORL3810 |
| Build #39 labels | OR5AC2 |
| Chromosomal location | 3:98,087,173-98,088,099 (+) |
| Cluster | 3@98 |
| Synteny | CLIC#9 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5AC1P | 72.96% | 307 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5AC26 | 77% | 304 |
| Mouse | Or5ac16 | 71% | 302 |
| Rat | Or5ac16 | 70% | 302 |
| Cow | OR5AC27P | 74% | 305 |
| Orang | OR5AC2P | 91% | 310 |
| Horse | OR5AC34 | 74% | 305 |
| Chimp | OR5AC1 | 74% | 307 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | AB528856 |
Sequence information
| Nucleotide sequence |
ATGGATATATCAGAGGGAAATAAGACTCTTGTGACAGAGTTTGTTCTCACAGGACTTACA GATCGACCATGGCTGCACGTCCTCTTCTTTGTTGTGTTTTTGGTGGTCTATCTCATCACC ATGGTGGGCAACCTTGGACTGATAGTTCTAATTTGGAACGACCCCCATCTTCATATGCCC ATGTACTTATTCCTTGGTGGTTTAGCCTTTTCAGATGCTTGTACTTCAACCTCTATAACC CCTAGGATGCTGGTCAATTTCTTAGACAAGACTGCAATGATATCCCTAGCTGAGTGCATC ACCCAGTTTTACTTTTTTGCTTCCAGTGCAACTACAGAATGCTTCCTCCTGGTGATGATG GCCTATGACCGCTATGTAGCCATATGTAATCCCTTGCTTTATCCAGTGATGATGTCCAAC AAACTCAGCGCTCAGTTGCTAAGTATTTCATATGTAATTGGTTTCCTGCATCCTCTGGTT CATGTGAGTTTACTATTGCGACTAACTTTCTGCAGGTTTAACATAATACATTATTTCTAC TGTGAAATTTTACAACTGTTCAAAATTTCATGCAATGGTCCATCTATTAACGCACTAATG ATATTTATTTTTGGTGCTTTTATACAAATACCCACTTTAATGACTATCATAATCTCTTAT ACTCGTGTGCTCTTTGATATTCTGAAAAAAAAGTCTGAAAAGGGCAGAAGCAAAGCCTTC TCCACATGCGGCGCCCATCTGCTTTCTGTCTCATTGTACTACGGAACTCTGATCTTCATG TATGTGCGTCCTGCATCTGGCTTAGCTGAAGACCAAGACAAAGTGTATTCTCTGTTTTAC ACGATTATAATTCCCCTGCTAAACCCATTTATTTACAGCTTGAGAAATAAAAAAGTCATG CATGCATTGAGAAGAGTTATAAGGAAG |
| Conceptual translation |
MDISEGNKTLVTEFVLTGLTDRPWLHVLFFVVFLVVYLITMVGNLGLIVLIWNDPHLHMP MYLFLGGLAFSDACTSTSITPRMLVNFLDKTAMISLAECITQFYFFASSATTECFLLVMM AYDRYVAICNPLLYPVMMSNKLSAQLLSISYVIGFLHPLVHVSLLLRLTFCRFNIIHYFY CEILQLFKISCNGPSINALMIFIFGAFIQIPTLMTIIISYTRVLFDILKKKSEKGRSKAF STCGAHLLSVSLYYGTLIFMYVRPASGLAEDQDKVYSLFYTIIIPLLNPFIYSLRNKKVM HALRRVIRK Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 3 | 97,806,701 | 97,806,700 | Ins(1) | -/A | rs11369970 (DbSNP) | |
| 3 | 97,806,163 | 97,806,162 | Ins(1) | -/G | rs35229249 (DbSNP) | |
| 3 | 97,806,616 | 97,806,616 | NS | A/G | I/M | rs4518168 (DbSNP) |
| 3 | 98,087,772 | 98,087,772 | NS | G/A | M/I | 1000GP (CEU, CHBJPT) |
| 3 | 98,087,461 | 98,087,461 | NS | G/C | A/P | 1000GP (CEU) |
| 3 | 98,087,898 | 98,087,898 | SYN | A/C | T/T | 1000GP (CEU) |
| 3 | 98,087,331 | 98,087,331 | NS | C/A | N/K | 1000GP (CHBJPT) |
| 3 | 100 | -100 | NS | C/A | N/K | 1000GP (YRI, YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 3 | 97,805,917 | 97,808,943 | CopyNumber | #109 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| N53K | Q145H | M200I | V223M | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | N | Q | I | V | 49.69 | 0.148 |
| 2 | N | Q | M | V | 43.55 | 0.148 |
| 3 | K | Q | M | V | 2.53 | 0.148 |
| 4 | N | H | M | V | 1.77 | 0.148 |
| 5 | K | Q | I | V | 1.46 | 0.148 |
| 6 | N | Q | M | M | 1.00 | 0.148 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5AC2.aApr07-unspliced | main_exon | CDS | chr3 | 98,087,173 | 98,088,099 | + |
| 3UTR | chr3 | 98,088,099 | 98,088,102 | + | ||