OR5AN1 Olfactory Receptor
| Gene Symbol | OR5AN11 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | AN |
| Pseudogene | No |
| CORP pseudogene probability score | 0.09 (functional) |
| Aliases | OR11-244, HsOR11.13.3, ORL3453 |
| External Ids | HGNC: 15255 GeneBank: AB065806, BK004508, NM_001004729 ORDB: ORL3453 |
| Build #39 labels | OR5AN1 |
| Chromosomal location | 11:59,364,459-59,365,391 (+) |
| Cluster | 11@59a |
| Synteny | CLIC#27 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5AN2P | 67.21% | 308 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5AN1E | 83% | 308 |
| Dog | OR5AN1D | 82% | 309 |
| Mouse | Or5an1 | 82% | 311 |
| Mouse | Or5an1b | 80% | 312 |
| Rat | Or5an1b | 80% | 312 |
| Rat | Or5an1 | 80% | 311 |
| Cow | OR5AN1L | 80% | 311 |
| Orang | OR5AN2 | 68% | 308 |
| Horse | OR5AN1J | 81% | 309 |
| Horse | OR5AN1I | 81% | 309 |
| Horse | OR5AN1H | 81% | 308 |
| Chimp | OR5AN1P | 100% | 306 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC140917 |
| GNF Atlas2 | gnf1h02107_at |
Sequence information
| Nucleotide sequence |
ATGACTGGGGGAGGAAATATTACAGAAATCACCTATTTCATCCTGCTGGGATTCTCAGAT TTTCCCAGGATCATAAAAGTGCTCTTCACTATATTCCTGGTGATCTACATTACATCTCTG GCCTGGAACCTCTCCCTCATTGTTTTAATAAGGATGGATTCCCACCTCCATACACCCATG TATTTCTTCCTCAGTAACCTGTCCTTCATAGATGTCTGCTATATCAGCTCCACAGTCCCC AAGATGCTCTCCAACCTCTTACAGGAACAGCAAACTATCACTTTTGTTGGTTGTATTATT CAGTACTTTATCTTTTCAACGATGGGACTGAGTGAGTCTTGTCTCATGACAGCCATGGCT TATGATCGTTATGCTGCCATTTGTAACCCCCTGCTCTATTCATCCATCATGTCACCCACC CTCTGTGTTTGGATGGTACTGGGAGCCTACATGACTGGCCTCACTGCTTCTTTATTCCAA ATTGGTGCTTTGCTTCAACTCCACTTCTGTGGGTCTAATGTCATCAGACATTTCTTCTGT GACATGCCCCAACTGTTAATCTTGTCCTGTACTGACACTTTCTTTGTACAGGTCATGACT GCTATATTAACCATGTTCTTTGGGATAGCAAGTGCCCTAGTTATCATGATATCCTATGGC TATATTGGCATCTCCATCATGAAGATCACTTCAGCTAAAGGCAGGTCCAAGGCATTCAAC ACCTGTGCTTCTCATCTAACAGCTGTTTCCCTCTTCTATACATCAGGAATCTTTGTCTAT TTGAGTTCCAGCTCTGGAGGTTCTTCAAGCTTTGACAGATTTGCATCTGTTTTCTACACT GTGGTCATTCCCATGTTAAATCCCTTGATTTACAGTTTGAGGAACAAAGAAATTAAAGAT GCCTTAAAGAGGTTGCAAAAGAGAAAGTGCTGC |
| Conceptual translation |
MTGGGNITEITYFILLGFSDFPRIIKVLFTIFLVIYITSLAWNLSLIVLIRMDSHLHTPM YFFLSNLSFIDVCYISSTVPKMLSNLLQEQQTITFVGCIIQYFIFSTMGLSESCLMTAMA YDRYAAICNPLLYSSIMSPTLCVWMVLGAYMTGLTASLFQIGALLQLHFCGSNVIRHFFC DMPQLLILSCTDTFFVQVMTAILTMFFGIASALVIMISYGYIGISIMKITSAKGRSKAFN TCASHLTAVSLFYTSGIFVYLSSSSGGSSSFDRFASVFYTVVIPMLNPLIYSLRNKEIKD ALKRLQKRKCC Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 59,132,399 | 59,132,398 | Ins(1) | -/T | rs34164503 (DbSNP) | |
| 11 | 59,132,798 | 59,132,798 | NS | C/G | F/L | rs7941190 (DbSNP) |
| 11 | 59,132,486 | 59,132,486 | SYN | A/G | L/L | rs73480618 (DbSNP) |
| 11 | 59,365,325 | 59,365,325 | NS | G/C | L/F | 1000GP (CEU, CHBJPT) |
| 11 | 59,364,749 | 59,364,749 | SYN | T/C | G/G | 1000GP (CEU) |
| 11 | 59,364,807 | 59,364,807 | NS | A/C | T/P | 1000GP (CHBJPT) |
| 11 | 100 | -100 | SYN | C/T | F/F | 1000GP (YRI, YRI) |
| 11 | 100 | -100 | NS | G/C | G/A | 1000GP (YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 11 | 59,131,832 | 59,134,864 | CopyNumber | #77 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| G3R | G162A | T247K | L289F | % Freq | CORP | |
|---|---|---|---|---|---|---|
| 1 | G | G | T | F | 63.29 | 0.171 |
| 2 | G | G | T | L | 35.41 | 0.171 |
| 3 | R | G | T | F | 0.69 | 0.171 |
| 4 | G | A | T | L | 0.31 | 0.171 |
| 5 | G | G | K | L | 0.31 | 0.171 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5AN1.aApr07-unspliced | main_exon | CDS | chr11 | 59,364,459 | 59,365,391 | + |
| 3UTR | chr11 | 59,365,391 | 59,365,394 | + | ||