OR5B21 Olfactory Receptor
| Gene Symbol | OR5B211 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | B |
| Pseudogene | No |
| CORP pseudogene probability score | 0.08 (functional) |
| Aliases | HsOR11.12.23 |
| External Ids | HGNC: 19616 GeneBank: XM_166926 |
| Build #39 labels | OR5B21 |
| Chromosomal location | 11:58,507,179-58,508,105 (-) |
| Cluster | 11@58 |
| Synteny | CLIC#27 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5B12 | 71.48% | 305 |
| OR5B1P | 67.87% | 305 |
| OR5B2 | 68.2% | 305 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5B2B | 70% | 305 |
| Mouse | Or5b21 | 86% | 308 |
| Rat | Or5b21 | 85% | 309 |
| Cow | OR5B12 | 67% | 305 |
| Orang | OR5B12P | 68% | 306 |
| Horse | OR5B12 | 70% | 305 |
| Chimp | OR5B21P | 96% | 309 |
Expression evidences
| Source | Accession |
|---|---|
| GNF Atlas2 | gnf1h11122_at |
Sequence information
| Nucleotide sequence |
ATGGAGAATAGCACAGAAGTGACAGAGTTTATCCTCTTGGGATTAACAGATGACCCCAAT CTTCAGATACCCCTCCTCCTGGCATTTTTATTCATCTACCTCATCACCCTGCTTGGGAAT GGGGGAATGATGGTGATCATCCACTCAGACTCCCATCTCCACACTCCAATGTACTTTTTC CTCAGTAACCTCTCCCTTGTAGACTTGGGTTACTCATCAGCTGTAGCCCCCAAAACGGTG GCTGCATTGCGGTCAGGGGACAAGGCCATCTCCTACGATGGATGTGCAGCTCAGTTCTTC TTCTTTGTGGGGTTTGCCACTGTTGAGTGCTACCTCCTGGCCTCCATGGCCTATGATCGC CATGCAGCGGTATGTAGGCCTCTTCATTACACCACCACCATGACAGCAGGTGTGTGTGCC CTCCTTGCTACTGGTTCCTATGTCTCTGGCTTCCTCAATGCCTCTATCCATGCAGCAGGC ACCTTCAGACTCTCCTTCTGTGGTTCTAATGAGATTAATCATTTCTTCTGTGACATTCCC CCACTCCTGGCTCTCTCATGCTCTGACACACGCATCAGCAAGTTGGTGGTCTTTGTGGCA GGCTTCAACGTCTTTTTCACCCTCCTGGTCATCCTTATTTCTTACTTCTTCATATGCATC ACCATTCAGAGGATGCATTCTGCTGAAGGGCAGAAGAAAGTCTTCTCCACCTGTGCTTCC CATCTCACTGCTTTGTCCATCTTCTATGGCACAATCATCTTCATGTACTTACAGCCCAAC TCCAGCCAGTCCGTGGACACAGACAAAATAGCCTCTGTGTTTTACACAGTGGTGATTCCC ATGCTGAATCCCTTGATATACAGCCTTAGGAACAAAGAAGTGAAAAGTGCTCTCTGGAAA ATACTCAACAAACTTTACCCCCAATAT |
| Conceptual translation |
MENSTEVTEFILLGLTDDPNLQIPLLLAFLFIYLITLLGNGGMMVIIHSDSHLHTPMYFF LSNLSLVDLGYSSAVAPKTVAALRSGDKAISYDGCAAQFFFFVGFATVECYLLASMAYDR HAAVCRPLHYTTTMTAGVCALLATGSYVSGFLNASIHAAGTFRLSFCGSNEINHFFCDIP PLLALSCSDTRISKLVVFVAGFNVFFTLLVILISYFFICITIQRMHSAEGQKKVFSTCAS HLTALSIFYGTIIFMYLQPNSSQSVDTDKIASVFYTVVIPMLNPLIYSLRNKEVKSALWK ILNKLYPQY Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 58,274,764 | 58,274,764 | NS | G/T | S/Y | rs58454093 (DbSNP) |
| 11 | 58,507,182 | 58,507,182 | SYN | T/C | Q/Q | 1000GP (CEU) |
| 11 | 58,507,314 | 58,507,314 | SYN | G/A | S/S | 1000GP (CEU) |
| 11 | 100 | -100 | NS | T/C | Y/C | 1000GP (YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 231 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| Y309C | I279F | S272Y | % Freq | CORP | |
|---|---|---|---|---|---|
| 1 | Y | I | S | 92.01 | 0.180 |
| 2 | Y | F | S | 5.80 | 0.180 |
| 3 | Y | I | Y | 1.53 | 0.180 |
| 4 | C | I | S | 0.66 | 0.180 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5B21.aApr07-unspliced | main_exon | 3UTR | chr11 | 58,507,176 | 58,507,179 | - |
| CDS | chr11 | 58,507,179 | 58,508,105 | - | ||