OR5B3 Olfactory Receptor
| Gene Symbol | OR5B31 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | B |
| Pseudogene | No |
| CORP pseudogene probability score | 0.04 (functional) |
| Aliases | OST129, OR11-239, HsOR11.12.20, ORL3811 |
| External Ids | HGNC: 8324 GeneBank: AB065545, BK004506, NM_001005469 ORDB: ORL3811 |
| Build #39 labels | OR5B3, OR5B13 |
| Chromosomal location | 11:58,402,468-58,403,409 (-) |
| Cluster | 11@58 |
| Synteny | CLIC#27 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5B12 | 74.36% | 312 |
| OR5B1P | 80.65% | 310 |
| OR5B2 | 77.2% | 307 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5B3B | 81% | 311 |
| Dog | OR5B2B | 80% | 313 |
| Mouse | Or5b3 | 81% | 307 |
| Rat | Or5b104 | 79% | 307 |
| Cow | OR5B140 | 75% | 313 |
| Orang | OR5B3P | 93% | 314 |
| Horse | OR5B2 | 80% | 309 |
| Chimp | OR5B1P | 80% | 310 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | BU101706 |
Sequence information
| Nucleotide sequence |
ATGGAAAATAAGACAGAAGTAACACAATTCATTCTTCTAGGACTAACCAATGACTCAGAA CTGCAGGTTCCCCTCTTTATAACGTTCCCCTTCATCTATATTATCACTCTGGTTGGAAAC CTGGGAATTATTGTATTGATATTCTGGGATTCCTGTCTCCACAATCCCATGTACTTTTTT CTCAGTAACTTGTCTCTAGTGGACTTTTGCTACTCTTCAGCTGTCACTCCCATCGTCATG GCTGGATTCCTTATAGAAGACAAGGTCATCTCTTACAATGCATGTGCTGCTCAAATGTAT ATCTTTGTAGCTTTTGCCACTGTGGAAAATTACCTCTTGGCCTCAATGGCCTATGACCGC TATGCAGCAGTGTGCAAACCCCTACATTACACCACAACCATGACAACAACTGTGTGTGCT CGTCTGGCCATAGGCTCCTACCTCTGTGGTTTCCTGAATGCCTCCATCCACACTGGGGAC ACATTTAGTCTCTCTTTCTGTAAGTCCAATGAAGTCCATCACTTTTTCTGTGATATTCCA GCAGTCATGGTTCTCTCTTGCTCTGATAGACATATTAGCGAGCTTGTTCTTATTTATGTT GTGAGCTTCAATATCTTTATAGCTCTCCTGGTTATCTTGATATCCTACACATTCATTTTT ATCACCATCCTAAAGATGCACTCAGCTTCAGTATACCAGAAGCCTTTGTCCACCTGTGCC TCTCATTTCATTGCAGTCGGCATCTTCTATGGGACTATTATCTTCATGTACTTACAACCC AGCTCCAGTCACTCCATGGACACAGACAAAATGGCACCTGTGTTCTATACAATGGTCATC CCCATGCTGAACCCTCTGGTCTATAGTCTGAGGAACAAGGAAGTGAAGAGTGCATTCAAG AAAGTTGTTGAGAAGGCAAAATTGTCTGTAGGATGGTCAGTT |
| Conceptual translation |
MENKTEVTQFILLGLTNDSELQVPLFITFPFIYIITLVGNLGIIVLIFWDSCLHNPMYFF LSNLSLVDFCYSSAVTPIVMAGFLIEDKVISYNACAAQMYIFVAFATVENYLLASMAYDR YAAVCKPLHYTTTMTTTVCARLAIGSYLCGFLNASIHTGDTFSLSFCKSNEVHHFFCDIP AVMVLSCSDRHISELVLIYVVSFNIFIALLVILISYTFIFITILKMHSASVYQKPLSTCA SHFIAVGIFYGTIIFMYLQPSSSHSMDTDKMAPVFYTMVIPMLNPLVYSLRNKEVKSAFK KVVEKAKLSVGWSV Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 100 | -100 | NS | T/C | K/R | 1000GP (YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | C/G | L/L | 1000GP (YRI, YRI, YRI, YRI, YRI) |
| 11 | 58,169,996 | 58,169,996 | NS | C/T | R/K | rs12279895 (DbSNP) |
| 11 | 58,170,025 | 58,170,025 | SYN | C/G | L/L | rs12271646 (DbSNP) |
| 11 | 58,170,106 | 58,170,106 | SYN | C/T | Q/Q | rs12279957 (DbSNP) |
| 11 | 58,170,143 | 58,170,143 | NS | C/G | G/A | rs11229409 (DbSNP) |
| 11 | 58,170,291 | 58,170,291 | NS | C/T | V/I | rs11229410 (DbSNP) |
| 11 | 58,170,342 | 58,170,342 | NS | C/T | A/T | rs11229411 (DbSNP) |
| 11 | 58,170,374 | 58,170,374 | NS | C/T | S/N | rs12280114 (DbSNP) |
| 11 | 58,170,462 | 58,170,462 | NS | A/G | C/R | rs12284790 (DbSNP) |
| 11 | 58,170,469 | 58,170,469 | SYN | A/C | V/V | rs11229412 (DbSNP) |
| 11 | 58,170,738 | 58,170,738 | NS | A/G | W/R | rs11229413 (DbSNP) |
| 11 | 58,170,780 | 58,170,780 | NS | A/T | F/I | rs17152659 (DbSNP) |
| 11 | 58,170,794 | 58,170,794 | NS | A/G | L/P | rs17152661 (DbSNP) |
| 11 | 58,402,523 | 58,402,523 | NS | T/C | K/R | 1000GP (CEU, CHBJPT) |
| 11 | 58,402,552 | 58,402,552 | SYN | C/G | L/L | 1000GP (CEU, CHBJPT) |
| 11 | 58,402,670 | 58,402,670 | NS | C/G | G/A | 1000GP (CEU, CHBJPT) |
| 11 | 58,402,818 | 58,402,818 | NS | T/C | I/V | 1000GP (CEU, CHBJPT) |
| 11 | 58,402,869 | 58,402,869 | NS | C/T | A/T | 1000GP (CEU, CHBJPT) |
| 11 | 58,402,901 | 58,402,901 | NS | T/C | N/S | 1000GP (CEU, CHBJPT) |
| 11 | 58,402,996 | 58,402,996 | SYN | C/A | V/V | 1000GP (CEU, CHBJPT) |
| 11 | 58,403,265 | 58,403,265 | NS | A/G | W/R | 1000GP (CEU, CHBJPT) |
| 11 | 58,403,307 | 58,403,307 | NS | T/A | I/F | 1000GP (CHBJPT) |
| 11 | 58,403,321 | 58,403,321 | NS | G/A | P/L | 1000GP (CEU) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 174 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| K296R | M266T | G247A | I198V | A181T | N170S | T158I | R141H | R141C | M57I | W49R | I35F | P30L | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | K | M | G | I | A | N | T | R | R | M | W | I | P | 64.36 | 0.109 |
| 2 | R | M | A | V | T | S | T | R | R | M | R | I | P | 28.19 | 0.109 |
| 3 | K | M | G | I | A | N | T | R | R | M | W | F | P | 3.23 | 0.109 |
| 4 | R | T | A | V | T | S | T | R | R | M | R | I | P | 1.15 | 0.109 |
| 5 | K | M | G | I | A | N | T | R | R | M | W | I | L | 1.00 | 0.109 |
| 6 | R | M | A | V | T | S | T | R | C | M | R | I | P | 0.77 | 0.109 |
| 7 | K | M | G | I | A | N | T | H | R | M | W | I | P | 0.46 | 0.109 |
| 8 | K | M | A | V | T | S | T | R | C | M | R | I | P | 0.23 | 0.109 |
| 9 | K | M | G | I | A | N | T | R | R | I | W | I | P | 0.23 | 0.505 |
| 10 | R | M | G | V | T | S | T | R | R | M | R | I | P | 0.08 | 0.109 |
| 11 | R | M | A | V | T | S | T | R | R | M | R | I | L | 0.08 | 0.109 |
| 12 | R | M | A | V | T | S | T | R | R | M | W | I | P | 0.08 | 0.109 |
| 13 | K | M | G | I | A | S | T | R | R | M | W | I | P | 0.08 | 0.109 |
| 14 | K | M | G | I | A | N | I | R | R | M | W | I | P | 0.08 | 0.109 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5B3.aApr07-unspliced | main_exon | 3UTR | chr11 | 58,402,465 | 58,402,468 | - |
| CDS | chr11 | 58,402,468 | 58,403,409 | - | ||