OR5H14 Olfactory Receptor
| Gene Symbol | OR5H141 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | H |
| Pseudogene | No |
| CORP pseudogene probability score | 0.1 (functional) |
| Aliases | HsOR3.3.5 |
| External Ids | HGNC: 31286 GeneBank: NM_001005514 |
| Build #39 labels | |
| Chromosomal location | 3:98,149,386-98,150,315 (+) |
| Cluster | 3@98 |
| Synteny | CLIC#9 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5H1 | 87.99% | 308 |
| OR5H3P | 89.03% | 310 |
| OR5H6 | 86.69% | 308 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5H13 | 76% | 308 |
| Mouse | Or5h26 | 75% | 308 |
| Rat | Or5h17 | 75% | 306 |
| Cow | OR5H13 | 78% | 308 |
| Orang | OR5H6 | 88% | 308 |
| Orang | OR5H8 | 86% | 308 |
| Orang | OR5H8BP | 86% | 256 |
| Horse | OR5H40 | 77% | 308 |
| Chimp | OR5H14BP | 91% | 310 |
| Chimp | OR5H7 | 89% | 308 |
| Chimp | OR5H1 | 88% | 308 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136984 |
Sequence information
| Nucleotide sequence |
ATGGAAGAGGAAAATGCAACATTGCTGACAGAGTTTGTTCTCACAGGATTTTTATATCAA CCACAGTGGAAAATACCCCTGTTCCTGGCATTCTTGGTAATATATCTCATCACCATCATG GGGAATCTTGGTCTGATTGCTGTCATCTGGAAAGACCCTCATCTTCATATCCCAATGTAC TTACTCCTTGGGAATTTAGCTTTTGTGGATGCTTTGTTATCATCCTCAGTGACTCTGAAG ATGCTGATCAACTTCTTAGCTAAGAGTAAGATGATATCTCTCTCTGAATGCAAGATACAG TTGTTTTCGTTTGCAATCAGTGTAACCACGGAATGTTTTCTCTTGGCAACAATGGCATAT GATCGCTATGTAGCCATATGCAAACCCTTACTTTATCCAGCCATTATGACCAATGGACTG TGCATCCGGCTATTAATCTTGTCATATGTAGGTGGTCTTCTTCATGCTTTAATCCATGAA GGATTTTTATTCAGACTAACCTTCTGTAACTCCAACATAATACAACACTTTTACTGTGAC ATTATCCCATTGTTAAAGATTTCTTATACTGATTCCTCTATTAACTTTCTAATGGTTTTT ATTTTTGCAGGTTCAATTCAAGTTTTTACCATAGGGACTGTTCTTATATCTTACATATTT GTCCTCTATACAATCTTGAAAAAGAAGTCTGTCAAAGGTATGAGAAAAGCCTTCTCCACC TGTGGAGCTCATCTCTTATCTGTATCTTTATACTATGGGCCCCTCGCCTTCATGTATATG GGCTCTGCATCCCCACAGGCTGATGACCAAGATATGATGGAGTCTCTATTTTACACTGTC ATAGTTCCTTTATTAAATCCCATGATCTACAGCCTGAGAAACAAGCAAGTAATAGCTTCA TTCACAAAAATGTTCAAAAGAAATGATGTT |
| Conceptual translation |
MEEENATLLTEFVLTGFLYQPQWKIPLFLAFLVIYLITIMGNLGLIAVIWKDPHLHIPMY LLLGNLAFVDALLSSSVTLKMLINFLAKSKMISLSECKIQLFSFAISVTTECFLLATMAY DRYVAICKPLLYPAIMTNGLCIRLLILSYVGGLLHALIHEGFLFRLTFCNSNIIQHFYCD IIPLLKISYTDSSINFLMVFIFAGSIQVFTIGTVLISYIFVLYTILKKKSVKGMRKAFST CGAHLLSVSLYYGPLAFMYMGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIAS FTKMFKRNDV Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 3 | 97,868,417 | 97,868,416 | Ins(1) | -/C | rs34013694 (DbSNP) | |
| 3 | 97,868,419 | 97,868,419 | NS | A/G | R/G | rs4241468 (DbSNP) |
| 3 | 97,868,795 | 97,868,795 | NS | A/G | Y/C | rs4857076 (DbSNP) |
| 3 | 97,868,422 | 97,868,422 | NS | A/G | N/D | rs73131400 (DbSNP) |
| 3 | 97,868,614 | 97,868,614 | NS | C/G | P/A | rs72932878 (DbSNP) |
| 3 | 97,868,296 | 97,868,296 | NS | C/T | R/W | rs7433910 (DbSNP) |
| 3 | 97,868,258 | 97,868,258 | NS | C/T | T/I | rs72927992 (DbSNP) |
| 3 | 97,868,766 | 97,868,766 | NS | G/T | W/C | rs12638928 (DbSNP) |
| 3 | 97,868,970 | 97,868,970 | SYN | A/T | S/S | rs12639519 (DbSNP) |
| 3 | 97,868,616 | 97,868,616 | SYN | C/T | P/P | rs4379004 (DbSNP) |
| 3 | 97,868,856 | 97,868,856 | SYN | C/T | F/F | rs72927996 (DbSNP) |
| 3 | 100 | -100 | SYN | T/C | F/F | 1000GP (YRI) |
| 3 | 100 | -100 | NS | G/A | M/I | 1000GP (YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| 3 | 97,868,130 | 97,871,159 | CopyNumber | #36 (Waszak) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| M59V | G64R | K98E | A134V | R143W | Y189C | M234I | A237T | A256D | N294K | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | M | R | K | A | R | C | M | A | A | N | 47.00 | 0.200 |
| 2 | M | G | K | A | R | Y | M | A | A | N | 35.79 | 0.206 |
| 3 | M | R | K | A | W | C | M | A | A | N | 9.68 | 0.200 |
| 4 | M | G | K | A | R | C | M | A | A | N | 2.15 | 0.200 |
| 5 | M | G | K | V | R | C | I | T | A | K | 1.00 | 0.417 |
| 6 | M | R | K | A | R | C | I | T | A | K | 0.84 | 0.417 |
| 7 | M | R | K | A | R | C | M | A | A | K | 0.61 | 0.200 |
| 8 | M | G | K | A | R | C | I | T | A | K | 0.54 | 0.417 |
| 9 | M | G | E | A | R | C | M | A | A | N | 0.38 | 0.200 |
| 10 | M | G | K | A | W | Y | M | A | A | N | 0.23 | 0.206 |
| 11 | M | G | K | A | W | C | M | A | A | N | 0.23 | 0.200 |
| 12 | M | R | K | A | R | Y | M | A | A | N | 0.23 | 0.206 |
| 13 | M | R | K | A | W | C | I | T | A | K | 0.15 | 0.417 |
| 14 | M | G | K | V | R | C | M | A | A | K | 0.15 | 0.200 |
| 15 | M | G | K | A | R | C | M | A | A | K | 0.15 | 0.200 |
| 16 | M | G | E | A | W | C | M | A | A | N | 0.15 | 0.200 |
| 17 | V | G | K | A | R | Y | M | A | A | N | 0.15 | 0.683 |
| 18 | M | R | K | V | R | C | M | A | A | N | 0.15 | 0.200 |
| 19 | M | G | K | A | R | Y | M | A | D | N | 0.15 | 0.206 |
| 20 | M | R | K | A | W | Y | M | A | A | N | 0.08 | 0.206 |
| 21 | V | R | K | A | R | C | M | A | A | N | 0.08 | 0.675 |
| 22 | M | R | K | A | R | C | I | A | A | K | 0.08 | 0.200 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5H14.aApr07-unspliced | main_exon | CDS | chr3 | 98,149,386 | 98,150,315 | + |
| 3UTR | chr3 | 98,150,315 | 98,150,318 | + | ||