OR5H6 Olfactory Receptor
Gene Symbol | OR5H61 (View this gene in GeneCards) |
Family | 5 |
Subfamily | H |
Pseudogene | No |
CORP pseudogene probability score | |
Aliases | OR3-11, HsOR3.3.11, ORL3094 |
External Ids | HGNC: 14767 GeneBank: AB065667, BK004374, NM_001005479 ORDB: ORL3094 |
Build #39 labels | OR5H6 |
Chromosomal location | 3:98,264,333-98,265,259 (+) |
Cluster | 3@98 |
Synteny | CLIC#9 |
Remarks | Segregating Pseudo Gene, a nonsynonymous SNP in a highly conserved amino-acid (rs9289564 and rs9853887) |
Most Similar ORs in Humans (Paralogs)
Symbol | Percent | Length |
---|---|---|
OR5H14 | 86.69% | 308 |
OR5H7P | 89.64% | 309 |
Most Similar ORs in other species (Orthologs)
Specie | Symbol | Percent | Length |
---|---|---|---|
Dog | OR5H13 | 76% | 308 |
Mouse | Or5h26 | 75% | 308 |
Rat | Or5h19-ps | 74% | 309 |
Cow | OR5H30 | 77% | 306 |
Orang | OR5H8 | 80% | 309 |
Orang | OR5H8BP | 82% | 256 |
Horse | OR5H8 | 76% | 309 |
Chimp | OR5H7 | 89% | 309 |
Chimp | OR5H14 | 88% | 308 |
Chimp | OR5H14BP | 86% | 308 |
Expression evidences
Source | Accession |
---|---|
mRNA | BC137524 |
GNF Atlas2 | gnf1h01994_at |
Sequence information
Nucleotide sequence |
ATGGAAGAGGAAAATGCAACATTGCTGACAGAGTTTGTTCTCACAGGATTTTTACATCAA CCTGACTGTAAAATACCGCTCTTCCTGGCATTCTTGGTAATATATCTCATCACCATCATG GGGAATCTTGGTCTAATTGTTCTCATCTGGAAAGACCCTCACCTTCATATCCCAATGTAC TTATTCCTTGGGAGTTTAGCCTTTGTGGATGCTTCGTTATCATCCACAGTGACTCCGAAG ATGCTGATCAACTTCTTAGCTAAGAGTAAGATGATATCTCTCTCTGAATGCATGGTACAA TTTTTTTCCCTTGTAACCACTGTAACCACAGAATGTTTTCTCTTGGCAACAATGGCATAT GATCGCTATGTAGCCATTTGCAAAGCTTTACTTTATCCAGTCATTATGACCAATGAACTA TGCATTCAGCTATTAGTCTTGTCATTTATAGGTGGCCTTCTTCATGCTTTAATCCATGAA GCTTTTTCATTCAGATTAACCTTCTGTAATTCCAACATAATACAACACTTTTACTGTGAC ATTATCCCATTGTTAAAGATTTCCTGTACTGATTCCTCTATTAACTTTCTAATGGTTTTT ATTTTCGCAGGTTCTGTTCAAGTTTTTACCATTGGAACTATTCTTATATCTTATACAATT ATCCTCTTTACAATCTTAGAAAAGAAGTCTATCAAAGGGATACGAAAAGCTGTCTCCACC TGTGGGGCTCATCTCTTATCTGTATCTTTATACTATGGCCCCCTCACCTTCAAATATCTG GGCTCTGCATCTCCGCAAGCAGATGACCAAGATATGATGGAGTCTCTATTTTACACTGTC ATAGTTCCTTTATTAAATCCCATGATCTACAGCCTGAGAAACAAGCAAGTAATAGCTTCA TTCACAAAAATGTTCAAAAGCAATGTT |
Conceptual translation |
MEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMY LFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAY DRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCD IIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVST CGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIAS FTKMFKSNV Protein domains and features |
Variations - SNPs
Chr | Start | End | Type | Variation | AA Change | SNP IDs |
---|---|---|---|---|---|---|
3 | 97,983,503 | 97,983,511 | In-Del(9) | -/GGTTACAGT | rs11279406 (DbSNP) | |
3 | 97,983,396 | 97,983,395 | Ins(9) | -/ACTGTAACC | rs11280482 (DbSNP) | |
3 | 97,983,265 | 97,983,265 | NS | A/C | E/A | rs4241472 (DbSNP) |
3 | 97,983,699 | 97,983,699 | NS | A/C | K/Q | rs58475490 (DbSNP) |
3 | 97,983,391 | 97,983,391 | NS | A/C/G | multi/S | rs2173236 (DbSNP) |
3 | 97,983,981 | 97,983,981 | NS | A/G | N/D | rs9871143 (DbSNP) |
3 | 97,983,942 | 97,983,942 | NS | A/G | T/A | rs9853906 (DbSNP) |
3 | 97,983,561 | 97,983,561 | NS | C/G | P/A | rs9289564 (DbSNP) |
3 | 97,983,253 | 97,983,253 | NS | C/T | P/L | rs36040433 (DbSNP) |
3 | 97,983,711 | 97,983,711 | NS | C/T | R/C | rs9853887 (DbSNP) |
3 | 97,983,664 | 97,983,664 | NS | C/T | S/L | rs16846784 (DbSNP) |
3 | 97,983,374 | 97,983,374 | SYN | A/G | L/L | rs4857358 (DbSNP) |
3 | 97,983,257 | 97,983,257 | SYN | C/G | L/L | rs2132894 (DbSNP) |
3 | 97,983,740 | 97,983,740 | SYN | C/T | S/S | rs36116717 (DbSNP) |
3 | 97,983,309 | 97,983,309 | SYN | C/T | L/L | rs73854590 (DbSNP) |
3 | 98,265,098 | 98,265,098 | NS | A/G | T/A | 1000GP (CEU, CHBJPT) |
3 | 98,264,413 | 98,264,413 | SYN | C/G | L/L | 1000GP (CEU, CHBJPT) |
3 | 98,264,547 | 98,264,547 | NS | C/T | S/L | 1000GP (CEU) |
3 | 98,265,137 | 98,265,137 | NS | G/A | D/N | 1000GP (CEU) |
3 | 98,264,758 | 98,264,758 | SYN | T/C | I/I | 1000GP (CHBJPT) |
3 | 100 | -100 | NS | C/T | H/Y | 1000GP (YRI, YRI, YRI) |
3 | 100 | -100 | SYN | C/G | L/L | 1000GP (YRI, YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
E27Q | H35Y | A46E | I55V | L64V | L130I | A145P | I158N | Q191K | C195R | P199S | I237M | V254F | T272A | D285N | % Freq | CORP | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | E | H | A | I | L | L | P | I | Q | R | P | I | V | A | N | 31.80 | 0.950 |
2 | E | H | A | I | L | L | A | I | Q | C | P | I | V | T | D | 25.50 | 0.950 |
3 | E | H | E | I | L | L | P | I | Q | R | P | I | V | A | D | 21.12 | 0.950 |
4 | E | H | A | I | L | L | P | I | Q | R | P | I | V | A | D | 9.37 | 0.950 |
5 | E | Y | A | I | L | L | P | I | K | C | S | I | V | A | D | 2.92 | 0.845 |
6 | E | H | A | I | L | I | P | I | Q | C | P | I | V | A | D | 2.53 | 0.652 |
7 | E | H | A | I | L | L | P | I | K | C | P | I | V | T | D | 2.00 | 0.950 |
8 | E | Y | A | I | L | L | P | I | Q | R | P | I | V | A | D | 0.92 | 0.845 |
9 | E | H | A | I | L | L | P | I | K | R | P | I | V | T | D | 0.84 | 0.950 |
10 | E | H | A | I | L | L | P | I | K | C | P | M | V | A | D | 0.38 | 0.950 |
11 | E | H | A | I | L | L | P | I | Q | C | P | I | V | A | N | 0.31 | 0.950 |
12 | E | H | A | I | L | L | P | I | Q | C | P | I | V | A | D | 0.31 | 0.950 |
13 | E | H | A | I | L | L | A | I | Q | R | P | I | V | T | D | 0.31 | 0.950 |
14 | E | H | A | I | L | L | P | I | Q | R | P | I | F | A | N | 0.15 | 0.967 |
15 | E | H | A | I | L | L | P | I | Q | C | P | I | V | T | D | 0.15 | 0.950 |
16 | E | H | A | I | L | L | A | I | Q | C | S | I | V | T | D | 0.08 | 0.950 |
17 | E | H | A | V | L | L | P | I | Q | R | P | I | V | A | D | 0.08 | 0.950 |
18 | E | H | E | I | L | L | P | N | Q | R | P | I | V | A | D | 0.08 | 0.950 |
19 | E | H | E | I | L | I | P | I | Q | R | P | I | V | A | D | 0.08 | 0.652 |
20 | E | H | E | I | L | L | P | I | Q | C | P | I | V | A | D | 0.08 | 0.950 |
21 | E | H | E | V | L | L | P | I | Q | C | P | I | V | A | D | 0.08 | 0.950 |
22 | Q | H | A | I | L | L | P | I | Q | R | P | I | V | A | N | 0.08 | 0.950 |
23 | Q | H | E | I | L | L | P | I | Q | R | P | I | V | A | D | 0.08 | 0.950 |
24 | E | H | A | I | L | L | A | I | Q | C | P | I | V | A | D | 0.08 | 0.950 |
25 | E | H | A | I | L | L | A | N | Q | C | P | I | V | T | D | 0.08 | 0.950 |
26 | E | H | A | I | L | L | P | I | Q | C | P | M | V | A | D | 0.08 | 0.950 |
27 | E | H | E | I | L | L | A | I | Q | C | P | I | V | T | D | 0.08 | 0.950 |
28 | E | H | E | I | V | L | P | I | Q | R | P | I | V | A | D | 0.08 | 0.950 |
29 | E | H | E | I | L | I | A | I | Q | C | P | I | V | T | D | 0.08 | 0.652 |
30 | E | H | A | V | L | L | P | I | Q | R | P | I | V | A | N | 0.08 | 0.950 |
31 | E | H | A | I | L | I | P | I | Q | C | P | I | V | A | N | 0.08 | 0.652 |
32 | E | H | A | I | L | L | P | I | K | C | P | I | V | A | D | 0.08 | 0.950 |
33 | E | H | A | I | L | L | P | I | Q | R | P | I | V | T | D | 0.08 | 0.950 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
Accession | Type | Chr | Start | End | Strand | |
---|---|---|---|---|---|---|
OR5H6.aApr07-unspliced | main_exon | 5UTR | chr3 | 98,264,285 | 98,264,333 | + |
CDS | chr3 | 98,264,333 | 98,265,259 | + | ||
3UTR | chr3 | 98,265,259 | 98,265,262 | + |