OR5K2 Olfactory Receptor
| Gene Symbol | OR5K21 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | K |
| Pseudogene | No |
| CORP pseudogene probability score | 0.27 (functional) |
| Aliases | OR3-9, HsOR3.3.17, ORL3095 |
| External Ids | HGNC: 14774 GeneBank: AB065457, BK004415, NM_001004737 ORDB: ORL3095 |
| Build #39 labels | OR5K2 |
| Chromosomal location | 3:98,497,681-98,498,628 (+) |
| Cluster | 3@98 |
| Synteny | CLIC#9 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5K1 | 94.79% | 307 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5K1 | 83% | 316 |
| Mouse | Or5k1 | 83% | 307 |
| Rat | Or5k1-ps | 83% | 307 |
| Cow | OR5K1 | 83% | 316 |
| Orang | OR5K1 | 93% | 307 |
| Horse | OR5K1P | 83% | 289 |
| Chimp | OR5K2P | 95% | 316 |
| Chimp | OR5K1 | 94% | 307 |
Expression evidences
| Source | Accession |
|---|---|
| ESTs | DA427661 |
| mRNA | BC136724 |
Sequence information
| Nucleotide sequence |
ATGGTTGAAGAAAATCATACCATGAAAAATGAGTTTATCCTCACAGGATTTACAGATCAC CCTGAGCTGAAGACTCTGCTGTTTGTGGTGTTCTTTGCCATCTATCTGATCACCGTGGTG GGGAATATTAGTTTGGTGGCACTGATATTTACACACTGTCGGCTTCACACACCAATGTAC ATCTTTCTGGGAAATCTGGCTCTTGTGGATTCTTGCTGTGCCTGTGCTATTACCCCCAAA ATGTTAGAGAACTTCTTTTCTGAGGGCAAAAGGATTTCCCTCTATGAATGTGCAGTACAG TTTTATTTTCTTTGCACTGTGGAAACTGCAGACTGCTTTCTTCTGGCAGCAGTGGCCTAT GACCGCTATGTGGCCATCTGCAACCCACTGCAGTACCACATCATGATGTCCAAGAAACTC TGCATTCAGATGACCACAGGCGCCTTCATAGCTGGAAATCTGCATTCCATGATTCATGTA GGGCTTGTATTTAGGTTAGTTTTCTGTGGATTGAATCACATCAACCACTTTTACTGTGAT ACTCTTCCCTTGTATAGACTCTCCTGTGTTGACCCTTTCATCAATGAACTGGTTCTATTC ATCTTCTCAGGTTCAGTTCAAGTCTTTACCATAGGTAGTGTCTTAATATCTTATCTCTAT ATTCTTCTTACTATTTTCAGAATGAAATCCAAGGAGGGAAGGGCCAAAGCCTTTTCTACT TGTGCATCCCACTTTTCATCAGTTTCATTATTCTATGGATCTATTTTTTTCCTATACATT AGACCAAATTTGCTTGAAGAAGGAGGTAATGATATACCAGCTGCTATTTTATTTACAATA GTAGTTCCCTTACTAAATCCTTTCATTTATAGTCTGAGAAACAAGGAAGTAATAAGTGTC TTAAGAAAAATTCTGCTGAAAATAAAATCTCAAGGAAGTGTGAACAAA |
| Conceptual translation |
MVEENHTMKNEFILTGFTDHPELKTLLFVVFFAIYLITVVGNISLVALIFTHCRLHTPMY IFLGNLALVDSCCACAITPKMLENFFSEGKRISLYECAVQFYFLCTVETADCFLLAAVAY DRYVAICNPLQYHIMMSKKLCIQMTTGAFIAGNLHSMIHVGLVFRLVFCGLNHINHFYCD TLPLYRLSCVDPFINELVLFIFSGSVQVFTIGSVLISYLYILLTIFRMKSKEGRAKAFST CASHFSSVSLFYGSIFFLYIRPNLLEEGGNDIPAAILFTIVVPLLNPFIYSLRNKEVISV LRKILLKIKSQGSVNK Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 3 | 98,217,178 | 98,217,178 | nonsense SNP | A/T | */Y | rs55639376 (DbSNP) |
| 3 | 98,217,050 | 98,217,050 | NS | A/C | N/H | rs59427166 (DbSNP) |
| 3 | 98,217,368 | 98,217,368 | NS | C/G | L/V | rs61733537 (DbSNP) |
| 3 | 98,216,681 | 98,216,681 | NS | C/T | R/C | rs1729959 (DbSNP) |
| 3 | 98,217,154 | 98,217,154 | SYN | C/T | T/T | rs58947289 (DbSNP) |
| 3 | 100 | -100 | NS | C/A | H/N | 1000GP (YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| L115V | R122H | T146S | H176N | Y218* | % Freq | CORP | |
|---|---|---|---|---|---|---|---|
| 1 | L | R | T | H | Y | 85.71 | 0.402 |
| 2 | L | R | T | H | * | 11.83 | 1.200 |
| 3 | L | R | T | N | Y | 1.84 | 0.510 |
| 4 | V | R | T | H | Y | 0.23 | 0.402 |
| 5 | L | H | T | H | Y | 0.23 | 0.923 |
| 6 | L | H | T | H | * | 0.08 | 1.200 |
| 7 | L | R | S | H | * | 0.08 | 1.200 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5K2.aApr07-unspliced | main_exon | CDS | chr3 | 98,497,681 | 98,498,628 | + |
| 3UTR | chr3 | 98,498,628 | 98,498,631 | + | ||