OR5K4 Olfactory Receptor
| Gene Symbol | OR5K41 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | K |
| Pseudogene | No |
| CORP pseudogene probability score | 0.13 (functional) |
| Aliases | HsOR3.3.14 |
| External Ids | HGNC: 31291 GeneBank: NM_001005517 |
| Build #39 labels | OR5K4 |
| Chromosomal location | 3:98,353,854-98,354,816 (+) |
| Cluster | 3@98 |
| Synteny | CLIC#9 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5K1 | 75.41% | 305 |
| OR5K2 | 72.46% | 305 |
| OR5K3 | 75.24% | 319 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5K1 | 77% | 307 |
| Mouse | Or5k17 | 78% | 317 |
| Rat | Or5k16 | 78% | 317 |
| Cow | OR5K8 | 78% | 307 |
| Orang | OR5K1 | 75% | 305 |
| Horse | OR5K24 | 80% | 306 |
| Chimp | OR5K3 | 76% | 319 |
Sequence information
| Nucleotide sequence |
ATGGCTAGGGAAAATCACTCCTTAGCAGCTGAATTCATCCTCATAGGATTTACAAATTAT CCAGAGCTGAAGACGCTTCTGTTTGTGGTGTTCTCTGCCATCTATCTGGTCACCATGGTG GGGAATCTTGGTCTGGTGGCATTAATTTATGTAGAGCGTCGTCTTCTCACACCAATGTAC ATCTTTCTGGGCAACCTGGCTCTGATGGATTCCTGCTGTTCCTGTGCTGTTACCCCCAAG ATGTTAGAGAATTTCTTTTCTGAGGATAGAATTATTTCCCTGTATGAATGTATGGCACAA TTTTATTTTCTCTGTCTTGCTGAAACCACAGACTGCTTTCTTCTGGCGACAATGGCCTAT GACCGCTATGTGGCCATATGCCACCCACTGCAGTACCACACCATGATGTCCAAGACGCTC TGCATTCGGATGACCACAGGGGCCTTCAAAGCTGGAAACCTGCATTCCATGATTCATGTA GGGCTTTTATTAAGGTTAACTTTCTGCAGGTCTAATAAAATTCACCACTTTTTCTGTGAT ATTCTTCCACTGTATAGACTCTCCTGTACAGATCCTTCTATTAATGAACTAATGATATAT ATCTTTTCAATACCAATTCAAATCTTTACCATTGCTACTGTCTTGATCTCTTATCTCTGC ATCCTTTTGACTGTTTTCAAAATGAAATCCAAGGAGGGAAGAGGTAAAGCATTTTCTACC TGTGCATCCCACTTTCTCTCTGTCTCAATATTTTACATTTGTCTTCTCATGTATATTGGA CCATCTGAAGAAGGAGATAAAGATACACCAGTGGCAATATTTTATGCAATAGTAATCCCA TTACTAAACCCTTTTATTTATAGTCTGAGAAATAAGGAGGTCATAAATGTTCTTAAAAAA ATTATGAGGAATTATAACATTCTTAAACAAACTTGCTCTATAGCAAATTTATTTTTAATT TAT |
| Conceptual translation |
MARENHSLAAEFILIGFTNYPELKTLLFVVFSAIYLVTMVGNLGLVALIYVERRLLTPMY IFLGNLALMDSCCSCAVTPKMLENFFSEDRIISLYECMAQFYFLCLAETTDCFLLATMAY DRYVAICHPLQYHTMMSKTLCIRMTTGAFKAGNLHSMIHVGLLLRLTFCRSNKIHHFFCD ILPLYRLSCTDPSINELMIYIFSIPIQIFTIATVLISYLCILLTVFKMKSKEGRGKAFST CASHFLSVSIFYICLLMYIGPSEEGDKDTPVAIFYAIVIPLLNPFIYSLRNKEVINVLKK IMRNYNILKQTCSIANLFLIY Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 3 | 98,073,592 | 98,073,592 | Del(1) | -/A | rs11288615 (DbSNP) | |
| 3 | 98,073,313 | 98,073,313 | NS | A/G | I/V | rs9822460 (DbSNP) |
| 3 | 98,354,008 | 98,354,008 | NS | A/C | E/A | 1000GP (CEU) |
| 3 | 98,354,118 | 98,354,118 | NS | G/A | D/N | 1000GP (CEU) |
| 3 | 98,354,469 | 98,354,469 | NS | A/G | I/V | 1000GP (CEU, CHBJPT) |
| 3 | 100 | -100 | NS | C/A | H/Q | 1000GP (YRI, YRI, YRI) |
| 3 | 100 | -100 | SYN | G/A | R/R | 1000GP (YRI) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| H6Q | Y20F | E52A | D89N | Y123F | I206V | A242S | I314V | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | H | Y | E | D | Y | I | A | I | 74.58 | 0.144 |
| 2 | H | Y | E | D | Y | V | A | I | 20.97 | 0.144 |
| 3 | Q | Y | E | D | Y | I | A | I | 2.38 | 0.144 |
| 4 | H | Y | E | N | Y | I | A | I | 0.61 | 0.144 |
| 5 | H | Y | E | D | Y | I | A | V | 0.46 | 0.144 |
| 6 | H | Y | E | D | Y | I | S | I | 0.31 | 0.144 |
| 7 | H | F | E | D | Y | I | A | I | 0.31 | 0.144 |
| 8 | H | Y | A | D | Y | I | A | I | 0.23 | 0.144 |
| 9 | H | Y | E | D | F | I | A | I | 0.08 | 0.144 |
| 10 | H | Y | E | D | F | V | A | I | 0.08 | 0.144 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5K4.aApr07-unspliced | main_exon | CDS | chr3 | 98,353,854 | 98,354,816 | + |
| 3UTR | chr3 | 98,354,816 | 98,354,819 | + | ||