OR5M11 Olfactory Receptor
| Gene Symbol | OR5M111 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | M |
| Pseudogene | No |
| CORP pseudogene probability score | 0.15 (functional) |
| Aliases | OR11-199, HsOR11.11.76, ORL493, ORL3433 |
| External Ids | HGNC: 15291 GeneBank: AF399521, BK004656, NM_001005245 ORDB: ORL493, ORL3433 |
| Build #39 labels | OR5M11 |
| Chromosomal location | 11:56,542,343-56,543,257 (-) |
| Cluster | 11@56 |
| Synteny | CLIC#26 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5M1 | 66.67% | 306 |
| OR5M10 | 66.99% | 306 |
| OR5M5P | 66.67% | 306 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5M5 | 68% | 306 |
| Mouse | Or5m11 | 86% | 306 |
| Mouse | Or5m11b | 85% | 306 |
| Rat | Or5m11 | 86% | 302 |
| Cow | OR5M10 | 68% | 306 |
| Orang | OR5E1P | 54% | 307 |
| Horse | OR5M5 | 67% | 306 |
| Chimp | OR5M1 | 67% | 306 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136951 |
| GNF Atlas2 | gnf1h05455_at |
Sequence information
| Nucleotide sequence |
ATGTCCAACACAAATGGCAGTGCAATCACAGAATTCATTTTACTTGGGCTCACAGATTGC CCGGAACTCCAGTCTCTGCTTTTTGTGCTGTTTCTGGTTGTTTACCTCGTCACCCTGCTA GGCAACCTGGGCATGATAATGTTAATGAGACTGGACTCTCGCCTTCACACGCCCATGTAC TTCTTCCTCACTAACTTAGCCTTTGTGGATTTGTGCTATACATCAAATGCAACCCCGCAG ATGTCGACTAATATCGTATCTGAGAAGACCATTTCCTTTGCTGGTTGCTTTACACAGTGC TACATTTTCATTGCCCTTCTACTCACTGAGTTTTACATGCTGGCAGCAATGGCCTATGAC CGCTATGTGGCCATATATGACCCTCTGCGCTACAGTGTGAAAACGTCCAGGAGAGTTTGC ATCTGCTTGGCCACATTTCCCTATGTCTATGGCTTCTCAGATGGACTCTTCCAGGCCATC CTGACCTTCCGCCTGACCTTCTGTAGATCCAGTGTCATCAACCACTTCTACTGTGCTGAC CCGCCGCTCATTAAGCTTTCTTGTTCTGATACTTATGTCAAAGAGCATGCCATGTTCATA TCTGCTGGCTTCAACCTCTCCAGCTCCCTCACCATCGTCTTGGTGTCCTATGCCTTCATT CTTGCTGCCATCCTCCGGATCAAATCAGCAGAGGGAAGGCACAAGGCATTCTCCACCTGT GGTTCCCATATGATGGCTGTCACCCTGTTTTATGGGACTCTCTTTTGCATGTATATAAGA CCACCAACAGATAAGACTGTTGAGGAATCTAAAATAATAGCTGTCTTTTACACCTTTGTG AGTCCGGTACTTAATCCATTGATCTACAGTCTGAGGAATAAAGATGTGAAGCAGGCCTTG AAGAATGTCCTGAGA |
| Conceptual translation |
MSNTNGSAITEFILLGLTDCPELQSLLFVLFLVVYLVTLLGNLGMIMLMRLDSRLHTPMY FFLTNLAFVDLCYTSNATPQMSTNIVSEKTISFAGCFTQCYIFIALLLTEFYMLAAMAYD RYVAIYDPLRYSVKTSRRVCICLATFPYVYGFSDGLFQAILTFRLTFCRSSVINHFYCAD PPLIKLSCSDTYVKEHAMFISAGFNLSSSLTIVLVSYAFILAAILRIKSAEGRHKAFSTC GSHMMAVTLFYGTLFCMYIRPPTDKTVEESKIIAVFYTFVSPVLNPLIYSLRNKDVKQAL KNVLR Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 56,310,356 | 56,310,356 | nonsense SNP | A/T | Y/* | rs17547284 (DbSNP) |
| 11 | 56,309,889 | 56,309,889 | NS | A/G | L/P | rs59345582 (DbSNP) |
| 11 | 56,309,896 | 56,309,896 | NS | C/G | V/L | rs17547207 (DbSNP) |
| 11 | 56,310,222 | 56,310,222 | NS | T/C | N/S | rs628524 (DbSNP) |
| 11 | 56,310,497 | 56,310,497 | SYN | C/T | P/P | rs72913727 (DbSNP) |
| 11 | 56,542,880 | 56,542,880 | nonsense SNP | A/T | Y/* | 1000GP (CEU) |
| 11 | 56,543,254 | 56,543,254 | NS | A/C | S/A | 1000GP (CEU) |
| 11 | 56,542,420 | 56,542,420 | NS | C/G | V/L | 1000GP (CEU) |
| 11 | 56,542,746 | 56,542,746 | NS | C/T | S/N | 1000GP (CEU, CHBJPT) |
| 11 | 56,543,021 | 56,543,021 | SYN | C/T | P/P | 1000GP (CEU, CHBJPT) |
| 11 | 56,542,413 | 56,542,413 | NS | G/A | P/L | 1000GP (CHBJPT) |
| 11 | 100 | -100 | NS | C/G | V/L | 1000GP (YRI, YRI, YRI) |
| 11 | 100 | -100 | SYN | C/T | P/P | 1000GP (YRI, YRI, YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 133 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| P283L | V281L | S172N | Y126* | R121C | A118V | P79L | L36V | % Freq | CORP | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | P | V | N | Y | R | A | P | L | 58.83 | 0.198 |
| 2 | P | V | S | Y | R | A | P | L | 32.80 | 0.198 |
| 3 | P | L | N | * | R | A | P | L | 4.76 | 1.200 |
| 4 | L | V | N | Y | R | A | P | L | 2.38 | 0.198 |
| 5 | P | V | S | Y | C | A | P | L | 0.38 | 0.814 |
| 6 | P | V | N | Y | R | V | P | L | 0.31 | 0.272 |
| 7 | P | V | N | Y | R | A | L | L | 0.15 | 0.400 |
| 8 | P | L | N | * | R | A | P | V | 0.15 | 1.200 |
| 9 | P | L | N | Y | R | A | P | L | 0.15 | 0.198 |
| 10 | P | V | N | Y | C | A | P | L | 0.08 | 0.814 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5M11.aApr07-unspliced | main_exon | 3UTR | chr11 | 56,542,340 | 56,542,343 | - |
| CDS | chr11 | 56,542,343 | 56,543,257 | - | ||