OR5M8 Olfactory Receptor
| Gene Symbol | OR5M81 (View this gene in GeneCards) |
| Family | 5 |
| Subfamily | M |
| Pseudogene | No |
| CORP pseudogene probability score | 0.61 (pseudogene) |
| Aliases | OR11-194, HsOR11.11.72, ORL3322 |
| External Ids | HGNC: 14846 GeneBank: AB065744, AF399520, BK004499, NM_001005282 ORDB: ORL3322 |
| Build #39 labels | OR5M8 |
| Chromosomal location | 11:56,490,438-56,491,370 (-) |
| Cluster | 11@56 |
| Synteny | CLIC#26 |
| Remarks |
Most Similar ORs in Humans (Paralogs)
| Symbol | Percent | Length |
|---|---|---|
| OR5M6P | 85.53% | 311 |
| OR5M7P | 89.03% | 310 |
Most Similar ORs in other species (Orthologs)
| Specie | Symbol | Percent | Length |
|---|---|---|---|
| Dog | OR5M3 | 72% | 302 |
| Mouse | Or5m8 | 84% | 312 |
| Rat | Or5m8 | 84% | 312 |
| Cow | OR5M8P | 77% | 300 |
| Orang | OR8D4 | 54% | 309 |
| Horse | OR5M5 | 69% | 309 |
| Chimp | OR5M7P | 91% | 302 |
Expression evidences
| Source | Accession |
|---|---|
| mRNA | BC136980 |
Sequence information
| Nucleotide sequence |
ATGAGAAGAAACTGCACGTTGGTGACTGAGTTCATTCTCCTGGGACTGACCAGTCGCCGG GAATTACAAATTCTCCTCTTCACGCTGTTTCTGGCCATTTACATGGTCACGGTGGCAGGG AACCTTGGCATGATTGTCCTCATCCAGGCCAACGCCTGGCTCCACATGCCCATGTACTTT TTCCTGAGCCACTTATCCTTCGTGGATCTGTGCTTCTCTTCCAATGTGACTCCAAAGATG CTGGAGATTTTCCTTTCAGAGAAGAAAAGCATTTCCTATCCTGCCTGTCTTGTGCAGTGT TACCTTTTTATCGCCTTGGTCCATGTTGAGATCTACATCCTGGCTGTGATGGCCTTTGAC CGGTACATGGCCATCTGCAACCCTCTGCTTTATGGCAGCAGAATGTCCAAGAGTGTGTGC TCCTTCCTCATCACGGTGCCTTATGTGTATGGAGCGCTCACTGGCCTGATGGAGACCATG TGGACCTACAACCTAGCCTTCTGTGGCCCCAATGAAATTAATCACTTCTACTGTGCGGAC CCACCACTGATTAAGCTGGCTTGTTCTGACACCTACAACAAGGAGTTGTCAATGTTTATT GTGGCTGGCTGGAACCTTTCTTTTTCTCTCTTCATCATATGTATTTCCTACCTTTACATT TTCCCTGCTATTTTAAAGATTCGCTCTACAGAGGGCAGGCAAAAAGCTTTTTCTACCTGT GGCTCCCATCTGACAGCTGTCACTATATTCTATGCAACCCTTTTCTTCATGTATCTCAGA CCCCCCTCAAAGGAATCTGTTGAACAGGGTAAAATGGTAGCTGTATTTTATACCACAGTA ATCCCTATGCTGAACCTTATAATTTATAGCCTTAGAAATAAAAATGTAAAAGAAGCATTA ATCAAAGAGCTGTCAATGAAGATATACTTTTCT |
| Conceptual translation |
MRRNCTLVTEFILLGLTSRRELQILLFTLFLAIYMVTVAGNLGMIVLIQANAWLHMPMYF FLSHLSFVDLCFSSNVTPKMLEIFLSEKKSISYPACLVQCYLFIALVHVEIYILAVMAFD RYMAICNPLLYGSRMSKSVCSFLITVPYVYGALTGLMETMWTYNLAFCGPNEINHFYCAD PPLIKLACSDTYNKELSMFIVAGWNLSFSLFIICISYLYIFPAILKIRSTEGRQKAFSTC GSHLTAVTIFYATLFFMYLRPPSKESVEQGKMVAVFYTTVIPMLNLIIYSLRNKNVKEAL IKELSMKIYFS Protein domains and features |
Variations - SNPs
| Chr | Start | End | Type | Variation | AA Change | SNP IDs |
|---|---|---|---|---|---|---|
| 11 | 56,258,232 | 56,258,232 | NS | G/T | N/K | rs61902888 (DbSNP) |
| 11 | 56,490,859 | 56,490,859 | NS | T/C | N/S | 1000GP (CEU) |
| 11 | 100 | -100 | NS | T/A | K/M | 1000GP (YRI) |
Variations - CNVs
| Chr | Start | End | Type | Sources |
|---|---|---|---|---|
| CopyNumber | 184 (Hasin) |
Haplotypes
Protein haplotypes were calculated using the 1000 genomes project as described in Olender T. et. al. BMC Genomics 2012.
| K226M | N205K | N171S | % Freq | CORP | |
|---|---|---|---|---|---|
| 1 | K | N | N | 97.31 | 0.750 |
| 2 | K | K | N | 1.77 | 0.750 |
| 3 | K | N | S | 0.54 | 0.750 |
| 4 | M | N | N | 0.38 | 0.750 |
AceView Gene Models
The information is based on AceView gene models, constructed from cDNA sequences. The information might be incomplete.
| Accession | Type | Chr | Start | End | Strand | |
|---|---|---|---|---|---|---|
| OR5M8.aApr07-unspliced | main_exon | 3UTR | chr11 | 56,490,435 | 56,490,438 | - |
| CDS | chr11 | 56,490,438 | 56,491,370 | - | ||